PROJECT 9. Biostatistics SRF

项目 9. 生物统计学 SRF

• 批准号: 8740619
• 负责人: Heidi L Weiss
• 金额: $ 15.44万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-08 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8740619
• 关键词: Address; Animals; Applications Grants; Bioinformatics; Biometry; Biostatistics Shared Resource; Cancer Center; Cancer Center Support Grant; Clinical; Clinical Data; Clinical Research; Clinical Trials; Collaborations; Complex; Consultations; Data; Data Analyses; Data Collection; Data Quality; Databases; Development; Educational process of instructing; Ensure; Faculty; Goals; Human Resources; In Vitro; Informatics; Intervention Studies; Kentucky; Laboratories; Malignant Neoplasms; Manuscripts; Mentors; Methodology; Mission; Monitor; Phase; Play; Preparation; Quality Control; Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Resources; Role; Safety; Sample Size; Sampling; Science; Secure; Services; Staging; Toxic effect; Training; Universities; abstracting; analytical method; anticancer research; computerized data processing; data management; design; experience; in vivo; member; mouse model; neoplasm registry; population based; pre-clinical; preclinical study; programs; research study

The Biostatistics Shared Resource Facility (BSRF) is a Markey Cancer Center (MCC)-managed resource providing comprehensive and centralized support that is readily accessible to cancer center investigators. The specific aims of the BSRF encompass support during study planning and study conduct and at the final stage of each project. In order to achieve these aims, our services are categorized broadly into: 1) study planning, power, and sample size calculations for grant applications, clinical trials, population-based studies, and preclinical experiments; 2) statistical analyses, including interim and final analysis for the entire spectrum of cancer research studies; 3) statistical programming for data quality control and data processing; and 4) mentoring, teaching, and general consultation to MCC investigators. We also collaborate closely with MCC's Clinical Research and Data Management SRF, Cancer Research Informatics SRF, and other MCC shared facilities. The shared resource personnel include six faculty statisticians, two master's-level statisticians, and a faculty bioinformatician. Collectively, they have extensive cancer-specific experience, expertise, and ongoing collaborations with investigators involved in studies ranging from laboratory, in vitro, in vivo studies in mouse models of cancer, translational, and bioinformatics studies in clinical samples, clinical trials, and population-based intervention studies. BSRF personnel are highly integrated with investigators across all research programs and interact closely with other SRFs at MCC to ensure comprehensive and seamless support. With personnel who are well-versed in all aspects of the biostatistical needs of MCC investigators, the dedicated BSRF team adds significant value to the conduct of research at the MCC.

生物统计学共享资源设施（BSRF）是由Markey癌症中心（MCC）管理的资源，提供了全面的集中支持，癌症中心研究人员很容易获得。 BSRF的具体目的包括在研究计划和研究行为期间以及每个项目的最后阶段的支持。为了实现这些目标，我们的服务大致分为：1）研究计划，权力和样本量计算，用于赠款应用，临床试验，基于人群的研究和临床前实验； 2）统计分析，包括整个癌症研究范围的临时和最终分析； 3）用于数据质量控制和数据处理的统计编程； 4）向MCC调查人员进行指导，教学和一般咨询。我们还与MCC的临床研究和数据管理SRF，癌症研究信息学SRF和其他MCC共享设施密切合作。共享的资源人员包括六位教师统计学家，两名大师级统计学家和一名教师生物信息学家。总的来说，它们具有广泛的癌症特异性经验，专业知识以及与参与研究的研究人员的持续合作，包括实验室，体外，体内研究小鼠模型，转化和生物信息学研究的临床样本，临床试验和基于人群干预研究的研究。 BSRF人员与所有研究计划中的研究人员高度融合，并与MCC的其他SRF紧密互动，以确保全面和无缝的支持。对于在MCC调查人员的生物统计需求的各个方面都精通的人员，专门的BSRF团队为MCC的研究进行了重要价值。