DIET AND GENOTYPE IN PRIMATE ATHERSCLEROSIS: VETERINARY SERVICES

灵长类动脉粥样硬化的饮食和基因型：兽医服务

• 批准号: 8172675
• 负责人: KAREN S RICE
• 金额: $ 49.78万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172675
• 关键词: Adipose tissue; Animal Technicians; Animals; Atherosclerosis; Biopsy; Birth Records; Blood; Breeding; Caring; Cholesterol; Collection; Computer Retrieval of Information on Scientific Projects Database; Databases; Diet; Dietary Fats; Funding; Genotype; Grant; Healthcare; Institution; Maintenance; Monitor; Muscle; Papio; Pregnancy; Primates; Procedures; Records; Research; Research Personnel; Resources; Services; Source; United States National Institutes of Health; Veterinarians; animal colony; base; feeding; femoral artery; liver biopsy; programs

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is Core C of the Program Project "Diet and Genotype in Primate Atherosclerosis". Core Unit C is responsible for maintaining the pedigreed baboon colony, managing the breeding groups, and conducting the experimental procedures using baboons. Colony maintenance includes daily care, i.e., feeding assigned diets, cleaning cages, observing animals for signs of illness, treating sick animals, and maintaining animal database records. Breeding colony management includes maintaining sire-dam assignments, monitoring dams for pregnancies, recording births in the animal database, and culling unproductive animals from the colony. Experimental procedures include administration of the high cholesterol, high fat dietary challenge, blood collections, femoral artery biopsies, liver biopsies, muscle biopsies, and adipose tissue biopsies. Animal caretakers are responsible for animal maintenance on a daily basis. Veterinarians or veterinary technicians provide health care, prepare experimental diet, and are responsible for experimental procedures.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 这是计划项目“灵长类动脉粥样硬化中的饮食和基因型”的核心C。 核心单元负责维持丘疹殖民地，管理育种组，并使用狒狒进行实验程序。殖民地维护包括日常护理，即喂养分配的饮食，清洁笼子，观察动物的疾病迹象，治疗生病的动物以及维护动物数据库记录。繁殖菌落的管理包括维持父亲 - 戴姆分配，监测怀孕的大坝，在动物数据库中记录出生，并从菌落中夺取非生产性的动物。实验程序包括给予高胆固醇，高脂肪饮食挑战，血液收集，股动脉活检，肝活检，肌肉活检和脂肪组织活检。动物看护者每天负责动物维护。兽医或兽医技术人员提供医疗保健，准备实验饮食，并负责实验程序。