VETERINARY SERVICES

兽医服务

• 批准号: 8376216
• 负责人: KAREN S RICE
• 金额: $ 51.29万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8376216
• 关键词: Accreditation; Adipose tissue; Age-Months; Animal Technicians; Animals; Atherosclerosis; Biopsy; Birth Records; Blood; Breeding; Caring; Cholesterol; Collection; Databases; Diet; Dietary Fats; Genotype; Healthcare; IACUC; Infant; Liver; Maintenance; Measures; Mediating; Monitor; Mothers; Muscle; Omentum; Papio; Pregnancy; Primates; Procedures; Recording of previous events; Records; Research; Research Personnel; Resources; Sampling; Structure; Summary Reports; Vasodilation; Veterinarians; animal colony; base; feeding; femoral artery; gang; liver biopsy; peer; programs

Core Unit C is responsible for maintaining the pedigreed baboon colony, managing the breeding groups, and conducting the experimental procedures using baboons. Colony maintenance includes daily care, i.e., feeding assigned diets, cleaning cages, observing animals for signs of illness, treating sick animals, and maintaining animal database records. Breeding colony management includes maintaining sire-dam assignments, monitoring dams for pregnancies, recording births in the animal database, and culling unproductive animals from the colony. Experimental procedures include administration of the high cholesterol, high fat dietary challenge, blood collections, femoral artery biopsies, liver biopsies, muscle biopsies, adipose tissue biopsies, and flow mediated vasodilation. Animal caretakers are responsible for animal maintenance on a daily basis. Veterinarians or veterinary technicians provide health care, prepare experimental diet, and are responsible for experimental procedures.

核心单元C负责维持纯种狒狒群体、管理繁殖群体、 并使用狒狒进行实验程序。蜂群维护包括日常护理，即 喂养指定的饮食、清洁笼子、观察动物的疾病迹象、治疗患病的动物，以及 维护动物数据库记录。繁殖群体管理包括维持母系 分配、监测水坝怀孕情况、在动物数据库中记录出生情况以及扑杀 来自群体的非生产性动物。实验程序包括施用高 胆固醇、高脂肪饮食挑战、血液采集、股动脉活检、肝脏活检、肌肉 活检、脂肪组织活检和血流介导的血管舒张。动物饲养员有责任 动物的日常维护。兽医或兽医技术人员提供医疗保健、准备 实验饮食，并负责实验程序。