MOOD/ANXIETY DISORDERS INITIATIVE-RAT/MOUSE MODELS OF DEPRESSION AND ANXIETY

情绪/焦虑障碍主动性——抑郁和焦虑的大鼠/小鼠模型

• 批准号: 8357554
• 负责人: MICHAEL NMN DAVIS
• 金额: $ 4.12万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357554
• 关键词: Affect; Amygdaloid structure; Anxiety; Anxiety Disorders; Fright; Funding; Grant; Measures; Mental Depression; Modeling; Moods; National Center for Research Resources; Neurons; Primates; Principal Investigator; Rattus; Reporting; Research; Research Infrastructure; Resources; Selective Serotonin Reuptake Inhibitor; Source; United States National Institutes of Health; cost; mouse model; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. During the reporting period, we have begun to evaluate how serotonin reuptake inhibitors and GSK compounds will affect our measures of fear vs. anxiety and whether over expression of CRF in CRF neurons in the amygdala will provide a novel model of anxiety.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的首席研究员可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 在报告期内，我们已经开始评估血清素再摄取抑制剂和 GSK 化合物将如何影响我们对恐惧与焦虑的测量，以及杏仁核 CRF 神经元中 CRF 的过度表达是否会提供一种新的焦虑模型。