METABOLIC PHENOTYPE IN CHILDREN AND ADOLESCENTS AT-RISK FOR TYPE 2 DIABETES (DM)

有 2 型糖尿病 (DM) 风险的儿童和青少年的代谢表型

• 批准号: 7952246
• 负责人: CATHERINE S MAO
• 金额: $ 1.02万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7952246
• 关键词: Adolescent; Child; Childhood; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Diabetes Mellitus; Funding; Goals; Grant; Institution; Logistic Regressions; Metabolic; Nature; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Phenotype; Regression Analysis; Relative (related person); Research; Research Personnel; Resources; Risk; Source; United States National Institutes of Health; Youth; design; trait

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. There are 2 components to this study. Pediatric DM2 Metabolic Phenotype Study: This portion of the study is designed to identify a panel of markers, a "Metabolic Phenotype", that is present in the DM2 children and not in lean control children. At Risk Youth Study: The goal of this portion of the study is to determine whether such a "Metabolic Phenotype" can be used to separate obese children and adolescents into two distinct groups, those with and those without the "Metabolic Phenotype". If this "Metabolic Phenotype" is present to some degree in obese youths without diabetes, then logistic regression analysis will be used to determine the relative contributions to the predictive nature of these traits.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究有2个组成部分。 小儿DM2代谢表型研究：这部分研究旨在识别DM2儿童而不是瘦对照儿童中存在的标记面板，即“代谢表型”。 在风险青年研究中：这部分研究的目的是确定这种“代谢表型”是否可用于将肥胖的儿童和青少年分为两个不同的群体，即患有“代谢表型”的群体。如果在没有糖尿病的肥胖年轻人中存在这种“代谢表型”，则将使用逻辑回归分析来确定对这些特征的预测性的相对贡献。