Vertebral Displacements & Ligament Strains during Simul. Spinal Mani./Gudavalli,R

椎骨移位

• 批准号: 7280089
• 负责人: JOEL G PICKAR
• 金额: $ 17.69万
• 依托单位: PALMER COLLEGE OF CHIROPRACTIC
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7280089
• 关键词: 3-Dimensional; Affect; Area; Biomechanics; Cadaver; Categories; Characteristics; Chemicals; Chiropractor; Clinical; Clinical Research; Computer Simulation; Condition; Connective Tissue; Data; Depth; Development; Effectiveness; Elements; Environment; Facet joint structure; Funding; Goals; Human; Joint Capsule; Knowledge; Ligaments; Localized; Location; Low Back Pain; Manuals; Measures; Mechanics; Methods; Modeling; Motion; Muscle; Musculoskeletal Diseases; National Center for Complementary and Alternative Medicine; Nervous system structure; Neuraxis; Nonlinear Dynamics; Patients; Procedures; Range; Rate; Research; Research Personnel; Rotation; Sensory Receptors; Simulate; Son; Specimen; Spinal; Spinal Manipulation; Stress; Stretching; Structure; Surface; Tissues; Traction; Universities; Variant; Vertebral column; Work; capsular ligament; chiropracty; college; millisecond; neuromechanism; osteopath; relating to nervous system; response; spine bone structure; vector

Spinal manipulation (SM) is widely used by chiropractors, osteopaths and physical therapists to treat musculoskeletal disorders of the spine. Clinical studies, however, have shown mixed results regarding the effectiveness of spinal manipulation to treat low back pain and have rarely quantified or controlled the delivery of the manipulative procedures. SM generally involves the application of manual loads to specific locations of the spine with the intent to induce intersegmental motions and stretch or compress ligaments, discs, and muscles. These anatomical structures contain sensory receptors which respond to changes in mechanical and chemical conditions and provide input to the central nervous system. There is evidence suggesting that mechanically stimulated neural responses, in particular, are important elements of the mechanism of action of SM. The National Center for Complementary and Alternative Medicine (NCCAM) has identified the need to biomechanically characterize manipulation procedures as an important area of research. Two broad categories of SM exist: high velocity low amplitude (HVLA) procedures, and low velocity variable amplitude (LWA) procedures. HVLA procedures deliver forces in a quick thrust with loading durations on the order of 100-200 milliseconds with approximately 200-500 N force. LWA procedures deliver a combination of regional spine loads and forces at localized vertebral levels delivered at a slow rate of loading and applied cyclically over a long duration on the order of 4-20 seconds with forces ranging from 80 N to 200 N. In addition to differences in temporal characteristics and loads, SM procedures vary in the point of application of these loads, and the directions along which loads are applied. Such variations may have clinical repercussions if mechanically sensitive tissues are affected in different ways. Our long term goal is to contribute to the understanding of SM mechanisms by characterizing the responses of intervertebral connective tissues to the full range of manipulative forces to provide more details about how specific SM characteristics affect the mechanical environment of spinal tissues. The objective of our proposed study is to understand the biomechanical effects of different manipulations. We propose a fouryear developmental study with experimental work at Palmer College of Chiropractic on human cadaver spines to measure directly the vertebral motions and the biomechanical strains of facet joint capsules during simulated HVLA SM and LWA SM. Co-Leaders at Stony Brook and Co-Investigators at University of Toledo will develop and validate a finite element model and estimate the strains of internal ligaments that cannot be measured. The validated computer model will be used to study the responses under varying SM load parameters.

脊椎治疗师，骨质疗法和物理治疗师广泛使用脊柱操纵（SM）来治疗 脊柱的肌肉骨骼疾病。然而，临床研究表明有关 脊柱操纵治疗下腰痛的有效性，很少量化或控制 交付操纵程序。 SM通常涉及将手动负载应用于特定 脊柱的位置，目的是诱导细胞节运动并拉伸或压缩韧带， 椎间盘和肌肉。这些解剖结构包含感官受体，这些受体应对变化 机械和化学条件，并为中枢神经系统提供输入。有证据 特别是，特别是机械刺激的神经反应是 SM的作用机理。国家补充医学中心（NCCAM）已有 确定了生物力学将操纵程序表征为重要领域的必要性 研究。存在两个广泛的SM类别：高速度低振幅（HVLA）程序，低速 速度变量振幅（LWA）程序。 HVLA程序在加载方面快速推动力提供力 大约200-500 n力的100-200毫秒级的持续时间。 LWA程序 在以缓慢速度传递的局部椎骨水平上提供区域脊柱负载和力的组合 在4-20秒的长度上循环循环加载和施加，力范围从 80 n至200 n。除了时间特征和载荷的差异外，SM程序在 这些负载的应用点以及施加载荷的方向。这种变化可能 如果机械敏感的组织以不同的方式影响，则具有临床影响。我们的长期 目标是通过表征对SM机制的理解做出贡献 椎间结缔组织到全部操纵力范围，以提供有关如何 特定的SM特性会影响脊柱组织的机械环境。我们的目标 拟议的研究是了解不同操纵的生物力学效应。我们提出了一个四年 人类尸体脊椎治疗学院的实验研究发展研究 棘以直接测量椎骨运动的椎骨运动和生物力学菌株 模拟HVLA SM和LWA SM。 Stony Brook的共同领导者和托莱多大学的共同研究员 将开发和验证有限元模型，并估算不可能的内部韧带的菌株 测量。经过验证的计算机模型将用于研究不同的SM负载下的响应 参数。