Effect of Spinal Mani on Sensorimotor Func in Back Pain Patients/Meeker, William

脊柱对背痛患者感觉运动功能的影响/Meeker, William

• 批准号: 7280090
• 负责人: JOEL G PICKAR
• 金额: $ 11.71万
• 依托单位: PALMER COLLEGE OF CHIROPRACTIC
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7280090
• 关键词: Address; Affect; Animal Model; Back Pain; Behavior; Biological; Biology; Biomechanics; Caring; Characteristics; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Data; Defect; Development; Etiology; Functional disorder; Funding; Goals; Guidelines; Health Status; Individual; Iowa; Lead; Light; Low Back Pain; Manuals; Measures; Muscle; NIH Program Announcements; National Center for Complementary and Alternative Medicine; Neurons; Outcome; Pain; Pathway interactions; Patient Self-Report; Patients; Pelvis; Physiological; Positioning Attribute; Posture; Procedures; Public Health; Randomized Controlled Clinical Trials; Range; Research; Review, Systematic (PT); Role; Sensorimotor functions; Source; Space Perception; Spinal; Spinal Manipulation; Subcategory; Subgroup; Symptoms; Time; Tissues; Universities; Variant; Vertebral column; Visit; Week; Work; base; chiropracty; clinical application; clinical effect; disability; dosage; improved; neurophysiology; response; symposium

PROVIDED. Spinal manipulation is a popular and widely used CAM treatment for back pain. It has been shown to be effective in a preponderance of clinical trials, but the reasons why manipulation works are unknown. The long-term goal for this study is to understand the physiological mechanisms of various forms of spinal manipulation in order to refine and improve this therapy for appropriately selected patients. Back pain patients demonstrate deficiencies in sensorimotor function. These may be related to the effects that manipulation appears to have on neurophysiology. Hence, the objective of this study is to assess the effects of high-velocity low-amplitude spinal manipulation(HVLA-SM) and low-velocity variable amplitude spinal manipulation (LVVA-SM) on three types of sensorimotor abilities in patients with low back pain. In collaboration with the University of Iowa, the Palmer Center for Chiropractic Research will pursue the following Specific Aims: 1) To determine the immediate pre-to-post changes from HVLA-SM and LVVA-SM, compared to a no-treatment control, on sensorimotor function as measured by: lumbo-pelvic repositioning ability, standing postural sway, and response to sudden trunk loading; 2) To determine the effects of 2 weeks (4 applications @ 2 per week) of HVLA-SM and LVVA-SM, compared to a no-treatment control, on sensorimotor function as measured by: lumbo-pelvic repositioning ability, standing postural sway, and response to sudden trunk loading; 3) To determine the effects of 6 weeks (12 applications @ 2 per week) of HVLA-SM and LVVA-SM on sensorimotor function as measured by: lumbo-pelvic repositioning ability, standing postural sway, and response to sudden trunk loading; 4) To explore whether changes in sensorimotor function are associated with changes in self-reported back pain intensity, related disability, or health status at 2 weeks (after 4 SM Visits) and at 6 weeks (after 12 SM Visits); and 5) To determine if sensorimotor function changes are greater in patients clinically classified as being most appropriate for manipulation. If spinal manipulation is demontrated to improve the sensorimotor functions of back pain patients and correlate with improvements in clinical symptoms and related disability, it will further define the appropriate clinical role of this CAM treatment, potentially enhance understanding about the etiology of back pain, and lead to improved treatment for a costly and common public health problem.

假如。 脊柱操纵是一种流行且广泛使用的CAM治疗，用于背痛。已经证明是 在大量临床试验中有效，但操纵起作用的原因尚不清楚。这 这项研究的长期目标是了解各种形式的脊柱的生理机制 为了改善和改善适当选择的患者的这种疗法的操作。背痛 患者表现出感觉运动功能的缺陷。这些可能与 操纵似乎具有神经生理学。因此，这项研究的目的是评估影响 高速度低振幅脊柱操纵（HVLA-SM）和低速变化振幅 下背痛患者的三种感觉运动能力的操纵（LVVA-SM）。在 与爱荷华大学合作，帕尔默脊椎治疗中心将追求 以下特定目的：1）确定HVLA-SM和LVVA-SM的立即到柱子的变化， 与无治疗控制相比，对感官函数的函数，如：lumbo-pelvic重新定位 能力，站立的姿势摇摆以及对突然的躯干负荷的反应； 2）确定2周的影响 （每周4个应用程序 @ 2）HVLA-SM和LVVA-SM，与无治疗控制 感觉运动功能由以下测量以下测量 对突然的躯干负荷的反应； 3）确定6周的影响（每周12个申请 @ 2） HVLA-SM和LVVA-SM在感觉运动函数上，如以下方式测量：Lumbo-Pelvic重新定位能力， 站立的姿势摇摆，以及对突然的躯干负荷的反应； 4）探索是否改变 感觉运动功能与自我报告的背痛强度，相关残疾或 2周的健康状况（4次访问后）和6周（12次SM访问后）； 5）确定是否 临床分类为最适合的患者的感觉运动功能变化更大 操纵。如果脊柱操纵被控制以改善背痛的感觉运动功能 患者并与临床症状和相关残疾的改善相关，它将进一步定义 这种CAM治疗的适当临床作用，有可能增强对背部病因的理解 疼痛，并改善治疗昂贵且普遍的公共卫生问题。