Enhanced digital imaging for improved vascular access

增强数字成像以改善血管通路

• 批准号: 7088945
• 负责人: GREGORY J FETZER
• 金额: $ 48.51万
• 依托单位: ARETE ASSOCIATES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-30 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7088945
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; cardiovascular imaging /visualization; catheterization; clinical research; digital imaging; image enhancement; image guided surgery /therapy; infrared radiation; luminescence

DESCRIPTION (provided by applicant): Phase I Arete Associates and Infrared Imaging Systems Inc. propose an innovative technology development that will safely and efficiently improve vascular access for cannulation by providing real-time high resolution enhanced imagery of the vascular structure in the region of interest. The proposed device overcomes deficiencies in current practice, and offers both improved patient care as well as lower overall cost. The device exploits a light source coupled to an optical receiver in transillumination geometry. In an early prototype received images are amplified using Night Vision technology to provide high resolution, high signal-to-noise ratio (SNR) vascular imagery. However in this effort a fusion of modern electro-optical and micro-electronic signal processing instrumentation will be used to produce a compact, power efficient sensor that provides high quality imagery without the need for the Night Vision image intensifier. The effort will demonstrate the utility and function of the instrument in both the laboratory and in human subject's studies in clinical settings. Arete Associates (Arete) and Infrared Imaging Systems, Inc (IRIS) have formed a strategic alliance (the Team) to achieve the goals of this program. The team was formed to build on the relative strengths of the organizations. Arete, acting, as the principle investigator will leverage its expertise in electro-optical instrumentation, signal processing and production expertise to design (Phase I) and build (Phase II) brassboard NIR vascular imaging instruments. IRIS will focus its efforts on optimizing sensor performance and guiding the brassboard design through interaction with the vascular imaging and medical community. The outcome of this Fast Track Phase I and Phase II effort will be proof of concept backed by extensive tests. In addition, the effort will produce a thoroughly tested design that will serve as the foundation for commercialization of the device.

描述（由申请人提供）： 第一阶段 Arete Associates 和红外成像系统公司提出了一项创新技术开发，通过提供感兴趣区域血管结构的实时高分辨率增强图像，安全有效地改善插管的血管通路。所提出的设备克服了当前实践中的缺陷，并改善了患者护理并降低了总体成本。 该设备利用与透照几何形状的光接收器耦合的光源。在早期原型中，使用夜视技术放大接收到的图像，以提供高分辨率、高信噪比 (SNR) 的血管图像。然而，在这项工作中，现代光电和微电子信号处理仪器的融合将用于生产紧凑、节能的传感器，无需夜视图像增强器即可提供高质量图像。这项工作将展示该仪器在实验室和临床环境中人体研究中的实用性和功能。 Arete Associates (Arete) 和 Infrared Imaging Systems, Inc (IRIS) 已组建战略联盟（团队）来实现该计划的目标。该团队的成立是为了发挥各组织的相对优势。 Arete 作为首席研究员，将利用其在电光仪器、信号处理和生产专业知识方面的专业知识来设计（第一阶段）和建造（第二阶段）黄铜板近红外血管成像仪器。 IRIS 将重点致力于优化传感器性能并通过与血管成像和医学界的互动来指导黄铜板设计。 快速通道第一阶段和第二阶段工作的成果将是经过广泛测试支持的概念证明。此外，这项工作还将产生经过彻底测试的设计，作为该设备商业化的基础。