Enhanced digital imaging for improved vascular access

增强数字成像以改善血管通路

• 批准号: 7070756
• 负责人: GREGORY J FETZER
• 金额: $ 88.53万
• 依托单位: ARETE ASSOCIATES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-30 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7070756
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; cardiovascular imaging /visualization; catheterization; clinical research; digital imaging; image enhancement; image guided surgery /therapy; infrared radiation; luminescence

DESCRIPTION (provided by applicant): Phase I Arete Associates and Infrared Imaging Systems Inc. propose an innovative technology development that will safely and efficiently improve vascular access for cannulation by providing real-time high resolution enhanced imagery of the vascular structure in the region of interest. The proposed device overcomes deficiencies in current practice, and offers both improved patient care as well as lower overall cost. The device exploits a light source coupled to an optical receiver in transillumination geometry. In an early prototype received images are amplified using Night Vision technology to provide high resolution, high signal-to-noise ratio (SNR) vascular imagery. However in this effort a fusion of modern electro-optical and micro-electronic signal processing instrumentation will be used to produce a compact, power efficient sensor that provides high quality imagery without the need for the Night Vision image intensifier. The effort will demonstrate the utility and function of the instrument in both the laboratory and in human subject's studies in clinical settings. Arete Associates (Arete) and Infrared Imaging Systems, Inc (IRIS) have formed a strategic alliance (the Team) to achieve the goals of this program. The team was formed to build on the relative strengths of the organizations. Arete, acting, as the principle investigator will leverage its expertise in electro-optical instrumentation, signal processing and production expertise to design (Phase I) and build (Phase II) brassboard NIR vascular imaging instruments. IRIS will focus its efforts on optimizing sensor performance and guiding the brassboard design through interaction with the vascular imaging and medical community. The outcome of this Fast Track Phase I and Phase II effort will be proof of concept backed by extensive tests. In addition, the effort will produce a thoroughly tested design that will serve as the foundation for commercialization of the device.

描述（由申请人提供）： 第一阶段 Arete Associates and Indrared Imaging Systems Inc.提出了一种创新的技术开发，该技术将通过在感兴趣地区提供实时高分辨率增强血管结构的图像，从而安全有效地改善插管的血管通道。提议的设备克服了当前实践中的缺陷，并提供了改善的患者护理以及较低的整体成本。 该设备利用了在透射几何形状中耦合到光学接收器的光源。在早期原型中，收到的图像通过夜视技术进行扩增，以提供高分辨率，高信噪比（SNR）血管图像。但是，在这种努力中，现代电流和微电子信号处理仪器的融合将用于生成紧凑的，电力有效的传感器，该传感器可提供高质量的图像，而无需夜视图像增强器。这项工作将证明该工具在实验室和人类受试者在临床环境中的研究中的效用和功能。 Arete Associates（ARETE）和红外成像系统公司（INC）（IRIS）已经成立了一个战略联盟（团队），以实现该计划的目标。该团队的成立是建立在组织的相对优势的基础上。 Arete，作为主要研究者将在电流仪器，信号处理和生产专业知识方面的专业知识来设计（I阶段I）和构建（II期）铜板NIR血管成像工具的专业知识。 Iris将通过与血管成像和医学界的互动来优化传感器性能和指导铜板设计。 这一快速轨道I和II期努力的结果将是通过广泛测试支持的概念证明。此外，这项工作将产生经过彻底测试的设计，将作为设备商业化的基础。