Environmental Field Emission Analytical SEM

环境场发射分析扫描电镜

• 批准号: 6501283
• 负责人: ANTONI P TOMSIA
• 金额: $ 76.25万
• 依托单位: UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-05-15 至 2004-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6501283
• 关键词: biomedical equipment purchase; scanning electron microscopy

DESCRIPTION (provided by applicant): This application is for an Environmental Field Emission Analytical Scanning Electron Microscope (EFESEM). Recent advances in SEM technology open new opportunities for biomaterials research. The developments of field emission electron sources and environmental chambers allow high resolution imaging (down to 1 nm) of wet, oily, dirty, outgassing, low-atomic number and non-conductive samples in their natural state without sample modification or preparation. These capabilities are a breakthrough in the analysis of biomaterials and their performance that will constitute an integral part in the development of a new generation of biomaterials. The EFESEM is one of the most versatile instruments for microstructural characterization. When coupled with a multifunction x-ray analyzer, concurrent micro-chemical analysis is possible. This multiuser facility will greatly enhance the research of six NIH investigators. The SEM facilities available to LBNL, UCSF and UCB faculty at present are limited and much less capable. Funding is requested for the acquisition of a state-of-the-art environmental field emission SEM, a Hitachi 4300 SE/N. The proposal has received broad based support from departmental (LBNL, UCSF and UCB) faculty; personnel from laboratory groups representing six PI's with current funding from NIH are projected as users. The Proposed microscope will be housed at the National Center for Electron Microscopy (NCEM) at the Lawrence Berkeley National Laboratory (LBNL). NCEM is a world leader in the application of transmission electron microscopy to microstructural characterization which will guarantee maintenance and operation of the instrument at the top condition, and also excellent training and support for the users named on the grant proposal.

描述（由申请人提供）：本申请适用于环境场发射分析扫描电子显微镜 (EFESEM)。 SEM 技术的最新进展为生物材料研究带来了新的机遇。场发射电子源和环境室的发展允许对自然状态下的潮湿、油性、肮脏、脱气、低原子序数和非导电样品进行高分辨率成像（低至1纳米），而无需样品修改或制备。这些能力是生物材料及其性能分析的突破，将构成新一代生物材料开发的一个组成部分。 EFESEM 是用于微观结构表征的最通用的仪器之一。当与多功能 X 射线分析仪结合使用时，可以同时进行微量化学分析。这个多用户设施将极大地加强 NIH 六名研究人员的研究。目前，劳伦斯伯克利国家实验室 (LBNL)、加州大学旧金山分校 (UCSF) 和加州大学伯克利分校 (UCB) 教师可以使用的 SEM 设施有限且能力较差。 需要资金购买最先进的环境场发射 SEM（日立 4300 SE/N）。该提案得到了院系（劳伦斯伯克利国家实验室、加州大学旧金山分校和加州大学伯克利分校）教师的广泛支持；代表 6 个 PI 的实验室小组的人员（目前由 NIH 资助）预计将作为用户。拟议的显微镜将安置在劳伦斯伯克利国家实验室 (LBNL) 的国家电子显微镜中心 (NCEM)。 NCEM 在透射电子显微镜微结构表征应用方面处于世界领先地位，这将保证仪器在最佳状态下的维护和操作，并为拨款提案中指定的用户提供良好的培训和支持。