Attentional Systems in Humans and Monkeys

人类和猴子的注意力系统

• 批准号: 6936287
• 负责人: Gaurav H Patel
• 金额: $ 2.68万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6936287
• 关键词: Macaca; attention; behavioral /social science research tag; biological models; brain electrical activity; brain mapping; cerebral ventricles; clinical research; frontal lobe /cortex; functional magnetic resonance imaging; gap junctions; goal oriented behavior; human subject; neural information processing; neural transmission; neuroanatomy; parietal lobe /cortex; predoctoral investigator; stimulus /response; temporal lobe /cortex; visual fields

DESCRIPTION (provided by applicant): Recent studies of human attention have uncovered a possible divide in the cortical areas underlying goal-directed attention and those underlying stimulus-driven reorienting of attention. The ventral frontoparietal system underlying stimulus-driven reorienting is of particular interest since it seems that damage to this system results in the syndrome of spatial neglect. Since many studies of this system take place in the macaque, our understanding of this frontoparietal system's role in attention will be greatly enhanced by understanding whether this model of attention generalizes to the macaque. I propose to perform a pair of experiments that will further our understanding of the homology between macaque and human frontoparietal systems underlying goal-directed control and stimulus-driven reorienting of attention. We will do this by classifying the degree of homology between the attention-related areas in both species according to function, topographic organization, and location. The results of these experiments will not only improve our understanding of the.attention system in both species, but will also serve as a guide to future fMRI and electrophysiological investigations of attention.

描述（由申请人提供）：对人类注意力的最新研究发现了目标指导注意的皮质区域以及那些基本刺激驱动的重新定位注意力方向的鸿沟。腹侧额心系统的基础刺激驱动的重新定位特别令人感兴趣，因为对该系统的损害似乎导致空间忽视综合征。由于该系统的许多研究都在猕猴中进行，因此我们对这种额产系统在注意力中的作用的理解将通过理解这种注意力模型是否概括为猕猴，从而大大增强。我建议进行一对实验，以进一步了解我们对猕猴和人类额产系统之间的同源性，而目标指导控制和刺激驱动的重新定位注意力的关注。我们将根据功能，地形组织和位置对与注意力相关的区域之间的同源性程度进行分类。这些实验的结果不仅会改善我们对这两种物种的注意力系统的理解，而且还将成为未来fMRI和电生理研究的指南。