Follow-up--Estimate Incidence of Mobility Disability

随访——估计行动障碍的发生率

• 批准号: 6521799
• 负责人: Jack M Guralnik
• 金额: --
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6521799
• 关键词: aging; functional ability; gait; human old age (65+); human subject; longitudinal human study; patient oriented research; prognosis; rehabilitation

The overarching goals of this research are to evaluate follow-up status, 1 to 2 years after baseline, of a cohort of persons aged 75-85 at baseline who were found to have functional limitations (EPESE performance battery score of 4-9) but who were able to walk 400 meters in a test done in the Hebrew Home rehabilitation unit. Specific questions to be addressed include: 1.What is the incidence of inability to walk 400 meters in at-risk older persons who were found to be able to walk this far at baseline? 2.What are the main chronic diseases, impairments, and demographic characteristics which predict incident mobility loss? 3.What questions can be asked to impute who will be unable to walk 400 meters in an objective test of walking this distance in the clinic. This methodologic work may allow for the imputation of mobility disability status in persons in a future clinical trial who refuse to come into the clinic or are not physically capable of coming to the clinic.

这项研究的总体目标是评估基线后1到2年的后续状态，这是一群在基线时75-85岁的人群，他们被发现具有功能限制（Epese绩效电池得分为4-9），但能够在希伯来语家庭恢复单位进行400米的步行400米。 要解决的具体问题包括： 1.在危险中的老年人中，无法在基线走这么远的老年人中行走400米的发生率是什么？ 2.哪些主要的慢性疾病，障碍和人口统计学特征可以预测事件流动损失？ 3.可以要求什么问题算上谁将无法在诊所步行这一距离的客观测试中步行400米。这项方法学的工作可能允许在以后的临床试验中拒绝进入诊所或没有身体能力来诊所的人的流动性残疾状况。