Physical Activity Monitoring In the LIFE Study Using the

生命研究中的身体活动监测使用

• 批准号: 7135639
• 负责人: Jack M Guralnik
• 金额: --
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7135639
• 关键词: actigraphy; body physical activity; clinical trials; exercise; gait; human subject; monitoring device; questionnaires

The major intervention in the LIFE pilot study for participants assigned to the exercise group will be walking. According to the treatment protocol, during the first six months as much as half of their increase in walking will be carried out ?at home? or in a non-supervised setting. During the second six months, at least 75% of the assigned walking will be non-supervised for most participants. To know if this intervention was accomplished, LIFE investigators need documentation that a significant increase in walking took place in the exercise participants versus the healthy aging class participants. Currently the protocol includes the use of pedometers, logs and the CHAMPS questionnaire to inform the investigators about the activity profile of each study participant. While all of these measurement tools are likely to provide useful data, none have been proven to provide an accurate and objective assessment of the daily physical activity profile of older, somewhat frail persons. The Actigraph is a small solid-state accelerometer/recorder (6.6 x 4.3 x 2.5 cm., 70 grams) that can store the number of times it moves x the rate of movement change (acceleration) on a continuous basis for up to a month (approximate battery life). It stores these ?counts? for specified times intervals, usually set at one-minute. For LIFE, this monitor will be worn on the right hip of each participant. The specific aims of this project are to determine the capability of the Actigraph accelerometer activity monitor to detect a significant difference in the physical activity level in a subset of subjects assigned to the LIFE exercise group versus the healthy aging class controls at six months into the study, (2) compare the assessment of amount of physical activity performed by a subset of subjects in the two treatment groups as determined by the CHAMPS physical activity questionnaire administered at 6 months and the Actigraph monitor using average number of ?accelerometer counts? per hour and number of minutes per day spent above a conditioning threshold, and (3) determine if data collected by the Actigraph monitor during the 400-meter walk at the 6-month evaluation can be used to help ?calibrate? or individualize the analysis of the Actigraph recorded during the 7 days of usual living.

LIFE 试点研究中对分配到运动组的参与者的主要干预措施是步行。根据治疗方案，在最初的六个月内，他们增加的步行量将有一半是在“家里”进行的。或在无人监督的环境中。在接下来的六个月中，对于大多数参与者来说，至少 75% 的指定步行将不受监督。为了了解这种干预措施是否完成，LIFE 调查人员需要记录证明运动参与者与健康老龄化类别参与者相比步行次数显着增加。目前，该协议包括使用计步器、日志和 CHAMPS 问卷来向研究人员通报每个研究参与者的活动概况。虽然所有这些测量工具都可能提供有用的数据，但没有一个被证明可以对老年人、有些虚弱的人的日常身体活动状况提供准确和客观的评估。 Actigraph 是一款小型固态加速度计/记录仪（6.6 x 4.3 x 2.5 厘米，70 克），可以连续存储一个月的移动次数 x 移动变化率（加速度） （大约电池寿命）。它存储这些“计数”？对于指定的时间间隔，通常设置为一分钟。对于 LIFE，该监视器将佩戴在每个参与者的右臀部。 该项目的具体目标是确定 Actigraph 加速度计活动监测器检测六个月后分配到 LIFE 运动组的一组受试者与健康老龄组对照组的体力活动水平显着差异的能力，（2）比较两个治疗组中一部分受试者进行的体力活动量的评估，该评估是通过 6 个月时进行的 CHAMPS 体力活动调查问卷和使用“加速计计数”平均数的 Actigraph 监测仪确定的。每小时和每天超过调节阈值的分钟数，以及 (3) 确定 Actigraph 监测器在 6 个月评估的 400 米步行过程中收集的数据是否可用于帮助“校准”。或对日常生活中 7 天记录的活动记录仪进行个性化分析。