HEALTH EFFECTS OF PESTICIDES

农药对健康的影响

• 批准号: 6106700
• 负责人: Andrew S. Rowland
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6106700
• 关键词: agriculture worker; clinical research; disease /disorder proneness /risk; dosage; fertility; human subject; low birth weight infant human; menstrual cycle disorder; nervous system disorder; pesticide biological effect; premature labor; questionnaires; spontaneous abortion

Summary of Work: The effects of chronic pesticide exposure among farmworkers to risk of neurologic disease. This study is being written up by Dr. Kamel. My role in the study was to help establish the initial contacts for the study, help with the initial planning of the study design, to develop the exposure assessment strategy for the study, and to help design the remaining sections of the questionnaire. The data for this project will be available for analysis in January,1999. Reproductive endpoints in the agricultural health study. I have been involved in developing the exposure assessment strategy for the study and will take the lead on analyses of menstrual cycle abnormalities, spontaneous abortions, low birth weight and preterm delivery, and pregnancy complications among women living on farms exposed to pesticides. We have started to look at the data on menstrual cycle abnormalities among women on farms. With about 2000 women in the dataset, this is one of the largest cohorts to look at risk factors for menstrual cycle abnormalities. We plan to look at medical and demographic determinants first and then to look at the possible effect of pesticides, particularly those that have estrogenic properties, on menstrual cycle function.

工作总结：慢性农药的影响 农场工人面临神经系统疾病的风险。这 卡迈勒博士正在撰写研究报告。我在这项研究中的角色是 帮助建立研究的初步联系，帮助进行初步的研究 规划研究设计，制定暴露评估 研究策略，并帮助设计其余部分 调查问卷。该项目的数据将可供 1999年1月分析。农业中的生殖终点 健康研究。我曾参与开发曝光 研究的评估策略并将带头进行分析 月经周期异常、自然流产、低产 体重和早产以及妊娠并发症 生活在接触农药的农场的妇女。我们已经开始 看看关于女性月经周期异常的数据 农场。数据集中约有 2000 名女性，这是其中之一 研究月经周期危险因素的最大队列 异常。我们计划研究医疗和人口统计 首先考虑决定因素，然后看看可能产生的影响 农药，特别是那些具有雌激素特性的农药 月经周期功能。