2022 Mammary Gland Biology GRC and GRS

2022年乳腺生物学GRC和GRS

• 批准号: 10462030
• 负责人: Nancy Ryan Gray
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-16 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10462030
• 关键词: Address; Area; Atmosphere; Basic Science; Biological; Biological Models; Biology; Breast; Breast Cancer Patient; Breast Cancer Prevention; Clinic; Clinical; Collaborations; Collection; Complex; Data; Development; Disease; Early Diagnosis; Environment; Event; Fostering; Funding; Goals; Heterogeneity; Hormone Receptor; Hour; Human; International; Italy; Lactation; Lead; Lesion; Malignant Neoplasms; Mammary gland; Mentorship; Molecular; Neoplasm Metastasis; Noninfiltrating Intraductal Carcinoma; Oral; Outcome; Participant; Physiology; Postdoctoral Fellow; Pregnancy; Prevention strategy; Receptor Signaling; Recording of previous events; Research; Research Personnel; Residual Tumors; Risk Factors; Role; Science; Scientist; Therapeutic; Thinking; Time; Training; Translational Research; Trees; Work; advanced breast cancer; anticancer research; base; breast cancer progression; breast stem cell; cancer diagnosis; cancer initiation; cancer therapy; career development; graduate student; improved; informal support; innovation; insight; interest; malignant breast neoplasm; mammary; mammary gland development; meetings; next generation; novel; novel strategies; peer coaching; posters; premalignant; programs; research study; stem cell biology; stem cells; student training; success; symposium; synergism; tool; tumor initiation; tumor progression; tumorigenesis

PROJECT SUMMARY The Gordon Research Conference on Mammary Gland Biology (GRC MGB) and the highly successful Gordon Research Seminar (GRS) that accompanies this meeting are unique amongst breast cancer conferences as they bring together a very diverse mix of scientists and clinician-scientists interested in the molecular and cellular mechanisms that govern normal mammary gland development, normal physiology, tumor initiation and progression and metastasis. There is a strong focus on breast cancer prevention and treatment (based on elucidating the early and later events that contribute to breast cancer onset and progression) and emerging `cutting edge' science relevant to the field. The Mammary Gland Biology GRC/GRS is the only conference that focuses on understanding the normal biology and development of the human breast and the mammary gland in model systems, and their relationship to tumorigenesis to understand events that give rise to breast cancer and has become a `must attend' event for mammary gland biologists and cancer researchers (particularly in basic and translational research areas). We aim to 1) uphold the MGB GRC tradition of providing a platform for established and new experts to present new scientific findings and novel ideas; 2) stimulate discussions between established investigators with trainees during informal sessions to train the next generation by its current leaders and promote mentorship. To fulfil Aim 1, we have organized a program including international experts to address a wide range of fundamental scientific issues, who will present their latest unpublished findings during the talks and during poster sessions. The conference program will include short talks selected from abstracts, providing opportunities for outstanding work by junior investigators and trainees. Plentiful time will be assigned for questions after each oral presentation to further encourage discussion. Discussions after the talks, during poster sessions, and more informally during meals and afternoons will stimulate forward thinking in both the mammary gland, breast biology, and breast cancer fields. Presentations and discussions of these new findings and innovations will contribute to deepen our understanding of breast cancer initiation, progression and metastasis and will provide the basis to develop further tools to tackle this heterogenous disease in the clinic. In addition, by bringing together a diverse collection of scientists to address emerging scientific problems bridging the breast cancer, prevention and risk factors, lactation and mammary development areas, this meeting will generate a unique and creative atmosphere that spurs innovative thinking and collaborations and contributes to important advances each year. To fulfil Aim 2, opportunities to attend the “Power Hour” and informal "Lunch with the Expert" sessions and “Under the tree discussions” where trainees and senior investigators meet to meet, discuss science, as well as opportunities and challenges in the context of career development, will enhance the development of the next generation of mammary gland/breast cancer biologists.

项目概要 戈登乳腺生物学研究会议 (GRC MGB) 和非常成功的戈登 本次会议附带的研究研讨会 (GRS) 在乳腺癌会议中是独一无二的： 他们汇集了对分子和细胞感兴趣的各种科学家和临床科学家 控制正常乳腺发育、正常生理、肿瘤发生和 乳腺癌的预防和治疗受到高度重视（基于） 阐明导致乳腺癌发生和进展的早期和晚期事件）和新出现的 乳腺生物学 GRC/GRS 是与该领域相关的“尖端”科学会议。 重点了解人类乳房和乳腺的正常生物学和发育 模型系统及其与肿瘤发生的关系，以了解导致乳腺癌和癌症的事件 已成为乳腺生物学家和癌症研究人员“必须参加”的活动（特别是在基础领域） 和转化研究领域）。 我们的目标是 1) 秉承 MGB GRC 的传统，为老牌和新晋专家提供展示平台 新的科学发现和新颖的想法；2）激发现有研究人员与受训者之间的讨论 在非正式会议期间，由现任领导人培训下一代并促进指导。 为了实现目标 1，我们组织了一项包括国际专家在内的计划来解决广泛的问题 基本科学问题，他们将在会谈和海报中展示其最新未发表的发现 会议议程将包括从摘要中选出的简短演讲，为大家提供机会。 初级研究者和实习生的出色工作将在每次口头后分配充足的时间来回答问题。 演讲后、海报会议等期间进一步鼓励讨论。 在进餐和下午非正式地进行，将激发乳腺、乳房生物学、 这些新发现和创新的演示和讨论将有助于 加深我们对乳腺癌发生、进展和转移的理解，并将为以下方面提供基础： 此外，通过汇集不同的方法，开发进一步的工具来在临床上解决这种异质性疾病。 聚集科学家来解决乳腺癌、预防和风险之间的新科学问题 因素、哺乳和乳腺发育领域，本次会议将产生独特的创意氛围 这激发了创新思维和合作，并每年为重大进步做出贡献。 为了实现目标 2，有机会参加“Power Hour”和非正式的“与专家共进午餐”会议，以及 “树下讨论”，学员和高级研究人员会面，讨论科学，以及 职业发展背景下的机遇与挑战，将提升未来的发展 一代乳腺/乳腺癌生物学家。