Core-003

核心003

• 批准号: 10409667
• 负责人: JAMES E. HEUBI
• 金额: $ 48.8万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10409667
• 关键词: Basic Science; Biological Markers; Clinical; Clinical Data; Clinical Investigator; Clinical Research; Clinical Sciences; Collaborations; Communities; Data; Dental; Development; Diagnostic tests; Discipline of Nursing; Disease; Faculty; Funding Opportunities; Future; Goals; Health; Health Occupations; High School Student; Institution; Intervention; Laboratories; Medical; Methods; Pilot Projects; Process; Program Development; Research; Research Personnel; Resources; Science; Students; Training; Training Programs; Translational Research; Translations; Universities; Workforce Development; acute care; base; career; clinical center; community engaged research; data dissemination; data management; design; health equity; high school; innovation; member; multidisciplinary; novel; programs; success; training opportunity; translational pipeline; translational scientist; translational study; undergraduate student

The University of Cincinnati’s Center for Clinical and Translational Science and Training (CCTST) is dedicated to providing all current and future members of the clinical and translational science workforce within our institution, community, and beyond with state-of-the-science educational opportunities. To accomplish this endeavor, we propose to further develop our Translational Workforce Development (TWD) program to provide training for early-stage, mid-career, and established investigators; boots-on-the-ground clinical research professionals; pre-professional trainees (allied health, pre-medical, nursing, dental, and medical assistants); and innovatively, community residents and high school students. Specifically, we will: 1) create new opportunities for formal training in community-engaged research for health equity, translational regulatory science, and acute care research; 2) develop a comprehensive training program for clinical research professionals to enhance the clinical research workforce, emphasizing a team-based approach; 3) expand and diversify the pipeline of translational researchers by exposing early-stage students (high school, allied health associate students, undergraduate health professions) to clinical research using existing and proposed community-engaged programs; and 4) design training for high-quality clinical data management and dissemination. To further support the workforce and development of translational research initiatives, the Pilot Translational and Clinical Studies Program (PTC) provides the means for junior and established basic science and clinical investigators to engage in multidisciplinary and collaborative team science approaches, develop efficient methods and processes, and generate robust preliminary data necessary for large-scale funding opportunities. The overall goal of the PTC is to accelerate the development of novel disease biomarkers, diagnostic tests, and therapies by facilitating translation of basic science laboratory discoveries across the Academic Health Center into novel clinical approaches and interventions. To build on the PTC’s success, we will innovatively expand the program by facilitating novel pilot translational and clinical studies through promotion of interdisciplinary and community collaboration and provide mechanisms for junior faculty to increase independence by providing active investigator assistance and a robust portfolio of pilot project mechanisms. Specifically, we will: 1) provide a comprehensive pilot project portfolio, including team-based and community-engaged support programs and resources, to promote collaboration and catalyze advancement of science across the translational research continuum throughout the Academic Health Center and beyond; and 2) develop training opportunities and resources for junior investigators to promote independence in clinical and translational research.

辛辛那提大学的临床与转化科学与培训中心（CCTST）是专门的 为我们提供临床和转化科学劳动力的所有当前和未来成员 机构，社区及以后的教育机会。实现这一目标 努力，我们建议进一步发展我们的转化劳动力发展（TWD）计划 为早期，职业和成熟的研究人员提供培训；地面临床靴 研究专业人员；专业的学员（联合健康，医学前，护士，牙科和医疗 助手）；并创新，社区居民和高中生。具体来说，我们将：1）创建 在社区参与卫生公平研究中进行正式培训的新机会，翻译的监管 科学和急性护理研究； 2）制定临床研究的全面培训计划 专业人士加强临床研究人员，强调基于团队的方法； 3）扩展和 通过暴露早期学生（高中，盟军健康 副学生，本科卫生专业人员）使用现有和拟议的临床研究 社区参与计划； 4）设计高质量临床数据管理的设计培训和 传播。为了进一步支持翻译研究计划的劳动力和发展，飞行员 翻译和临床研究计划（PTC）为初级和建立的基本提供了手段 科学和临床研究人员从事多学科和协作团队科学方法， 开发有效的方法和过程，并生成大规模必需的强大初步数据 资金机会。 PTC的总体目标是加速新型疾病的发展 通过促进基础科学实验室发现的翻译，生物标志物，诊断测试和疗法 整个学术健康中心都采用了新的临床方法和干预措施。在PTC上建立 成功，我们将通过促进新型飞行员翻译和临床研究来创新扩展该计划 通过促进跨学科和社区合作，并为初级教师提供机制 通过提供积极的调查员协助和强大的飞行员项目组合来增加独立性 机构。特别是：1）提供全面的试点项目组合，包括基于团队和 社区参与的支持计划和资源，以促进合作和促进 翻译研究的科学在整个学术保健中心及其他地区仍在继续；和 2）为初级调查人员开发培训机会和资源，以促进临床和 翻译研究。