Cincinnati Center for Clinical and Translational Sciences and Training

辛辛那提临床和转化科学与培训中心

• 批准号: 9261619
• 负责人: JAMES E. HEUBI
• 金额: $ 341.94万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9261619
• 关键词: Acute; Adult; Age; Caring; Child; Clinical; Clinical Informatics; Clinical Research; Clinical Sciences; Clinical Trials; Clinical effectiveness; Collaborations; Communities; Development; Discipline; Education; Educational process of instructing; Elderly; Environment; Environmental Exposure; Environmental Health; Ethics; Family; Fostering; Future; Goals; Government Officials; Health; Healthcare; Informatics; Information Technology; Learning; Longevity; Master of Science; Methods; Multicenter Trials; Participant; Patients; Performance; Population; Process; Provider; Race; Recruitment Activity; Research; Research Methodology; Research Personnel; Science; Scientist; Services; Site; Training; Translational Research; Trust; Underrepresented Minority; Universities; Vision; Work; base; biomedical informatics; career development; data integration; design; health care delivery; health disparity; improved; innovation; medical specialties; member; named group; next generation; patient oriented research; practice-based research network; programs; sex; success

The vision of the Center for Clinical and Translational Science and Training (CCTST) at the University of Cincinnati is to be the Greater Cincinnati portal of entry for support of clinical and translational research with a goal to enfranchise stakeholders from a broad base to integrate research into healthcare delivery, improve community wellness, foster effective, efficient multisite trials, and train the clinical and translational research workforce of the future. We will realize this vision through three aims: (1) Empower stakeholders in the process of integrating research with healthcare practice and community wellness, (2) Create the workforce of the future, and (3) Optimize efficiency and effectiveness of clinical research. Building on the successes of the last 6 years, we propose innovative changes to existing programs and creation of new programs designed to provide support for high quality cutting-edge research done by teams of scientists. Building on our existing programs, we propose to (1) provide innovative programs in career development for a wide range of learners, (2) develop new pilot programs to support creation of solutions for obstacles to research, (3) expand our community engagement program to extend beyond Greater Cincinnati to stakeholders across the U.S., (4) provide more comprehensive support by biomedical informatics for the services provided by the CCTST, (5) expand support for patient-oriented research, and (6) help overcome regulatory and ethical challenges that impede clinical research in local and multisite studies. We propose innovative efforts directed toward fostering learning health networks and creating a Research Commons to provide more comprehensive support to investigators. We will focus on (1) teaching and implementing team science principles and encouraging collaboration across a variety of disciplines and stakeholders, (2) consolidation of clinical trials support across the academic health center by creating Cinci-HERO to help multicenter trials for which the CCTST affiliates are the leads (including serving as the IRB of record) or site participants and recruitment of populations across the lifespan including underrepresented minorities, those with environmental exposures and health disparities, and (3) acute care research and lifespan data integration that takes advantage of institutional strengths.

临床与转化科学与培训中心（CCTST）的愿景 辛辛那提大学将成为辛辛那提的大型入学门户，以支持临床和 转化研究的目标是使从广义基础的利益相关者获得合法性的利益相关者 研究医疗保健提供，改善社区健康，促进有效，高效的研究 多站点试验，并培训未来的临床和转化研究劳动力。我们将 通过三个目的实现这一愿景：（1）在整合的过程中授权利益相关者 通过医疗保健实践和社区健康研究，（2）创建 未来，以及（3）优化临床研究的效率和有效性。建立在 过去6年的成功，我们提出了对现有计划和创建的创新更改 旨在为高质量尖端研究提供支持的新计划 科学家团队。在我们现有计划的基础上，我们建议（1）提供创新的 （2）制定新的试点计划的职业发展计划 支持创建解决障碍的解决方案，（3）扩大我们的社区参与 超越辛辛那提延伸到美国利益相关者的计划，（4）提供更多 生物医学信息学为CCTST提供的服务的全面支持，（5） 扩大对以患者为导向的研究的支持，（6）有助于克服监管和道德 阻碍本地和多站点研究中临床研究的挑战。我们提出创新 致力于促进学习健康网络并建立研究共享的努力 为调查人员提供更全面的支持。我们将专注于（1）教学和 实施团队科学原则，并鼓励在各种 学科和利益相关者，（2）整合整个学术的临床试验支持 通过创建CCTST分支机构的多中心试验来创建卫生中心 是线索（包括作为记录的IRB）还是现场参与者以及招聘 整个生命周期中的人口包括代表性不足的少数民族， 环境暴露和健康差异，以及（3）急性护理研究和寿命数据 利用机构优势的整合。