Core-001

核心001

• 批准号: 10409665
• 负责人: JAMES E. HEUBI
• 金额: $ 59.29万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10409665
• 关键词: Address; Basic Science; Clinical; Clinical Sciences; Communities; Data; Data Aggregation; Data Analyses; Development; Engineering; Health; Health Care Research; Healthcare; Healthcare Systems; Informatics; Knowledge; Learning; Medical center; Participant; Pediatric Hospitals; Persons; Policies; Procedures; Research; Source; System; Technology; Training; Translational Research; Universities; clinical center; data infrastructure; improved; innovation; interoperability; knowledge translation; literacy; literate; operation; programs

The ability to generate, share, and analyze data is fundamental to the operation of the Center for Clinical and Translational Science and Training (CCTST) and participation in wider CTSA networks. Effective fulfillment of these principles requires robust data infrastructure and well-formulated policies and procedures, but more importantly, the development of a highly participatory, informatics- and data-literate research community that embraces best practices alongside innovation. We believe that fulfillment of these data-centric objectives will allow greater discovery, inference, understanding, and translation of knowledge for improved health and wellness. To achieve these objectives, we will focus on the development and implementation of disciplinebased local learning systems to improve data aggregation, data utilization, and informatics literacy, with a focus on our own health care systems [University of Cincinnati (UC) Health and Cincinnati Children’s Hospital Medical Center]. We expect to identify, aggregate, uniformly represent, and make interoperable health care data from a variety of basic and translational science realms, clinical systems, and community sources. We also expect to broadly provide the means for all Cincinnati stakeholders to more effectively access and utilize these biomedical data, and to widely disseminate knowledge derived from such data that is relevant to improving health and health care. Finally, we expect to maximally increase literacy for understanding and using informatics approaches for all Cincinnati stakeholders, to enable our workforce and community to best utilize data for improving health and health care. The resulting programs will be accessible across our spectrum of stakeholders, and their products will be available to all community and CTSA participants. These programs will leverage existing data, technology, and people, and the programs will logically organize and build upon these components to synergistically and continually identify new data, analysis, and technology needs, and to cocreate new informatics solutions for our health care research concentrations. We will be building on our past accomplishments to strengthen this construct and address the challenges of efficient, universal access to biomedical data for knowledge engineering and application.

生成，共享和分析数据的能力是临床中心和 转化科学与培训（CCTST）以及参与更广泛的CTSA网络。有效实现 这些原则需要强大的数据基础架构以及良好的政策和程序，但更多 重要的是，发展一个高度参与，信息和数据量学研究社区的发展 拥抱最佳实践以及创新。我们认为，以数据为中心的对象实现 允许对知识的发现，推理，理解和翻译进行更多的发现，以改善健康 健康。为了实现这些目标，我们将专注于基于纪律的发展和实施 通过A的本地学习系统，以改善数据汇总，数据利用和信息素养 专注于我们自己的医疗保健系统[辛辛那提大学（UC）健康和辛辛那提儿童医院 医疗中心]。我们希望识别，汇总，统一代表并提供可互操作的医疗保健 来自各种基本和翻译的科学领域，临床系统和社区来源的数据。我们 还希望广泛地为所有辛辛那提利益相关者提供更多的手段，以便更有效地访问和利用 这些生物医学数据，并广泛传播与此类数据相关的知识 改善健康和医疗保健。最后，我们希望最大化识字和使用的识字率 为所有辛辛那提利益相关者提供信息的方法，以使我们的员工和社区能够最好地利用 改善健康和医疗保健的数据。最终的程序将在我们的范围内访问 利益相关者及其产品将适用于所有社区和CTSA参与者。这些程序将 利用现有的数据，技术和人员，这些程序将在逻辑上组织和建立这些计划 协同，连续识别新数据，分析和技术需求的组件，并与 我们的医疗保健研究集中的新信息解决方案。我们将建立过去 成就加强这种结构并应对高效，普遍访问的挑战 知识工程和应用的生物医学数据。