Promoting Diversity in the UNM METALS SRC through Risk-Reduction Research on Tribal Lands

通过部落土地风险降低研究促进 UNM METALS SRC 的多样性

• 批准号: 10395130
• 负责人: Johnnye L Lewis
• 金额: $ 5万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2022-09-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10395130
• 关键词: Affect; Area; Basic Science; Chemistry; Collaborations; Communities; Complement; Development; Ecology; Funding Opportunities; Goals; Health; Immobilization; Lead; Master of Science; Mentors; Metal exposure; Metals; Microscopy; Mining; Motivation; Navajo; New Mexico; Oxidation-Reduction; Phase; Plants; Poaceae; Pueblo Race; Research; Research Personnel; Resources; Risk Reduction; Role; Signal Recognition Particle; Site; Spectrum Analysis; Students; Superfund; Symbiosis; Training; Translations; Universities; Work; aqueous; career development; community engaged research; community engagement; experimental study; fungus; graduate student; metal poisoning; novel strategies; plant fungi; remediation; tool; toxic metal; tribal lands; undergraduate student; uptake

Project Summary The goal of this SRP Research Supplement to Promote Diversity in Health-Related Research is to complement efforts for Phase 1 of the University of New Mexico’s Metals Exposure and Toxicity Assessment on Tribal Lands in the Southwest (UNM METALS) Superfund Basic Research Center (SRC) Environmental Project 1 (EP1). The focus of EP1 is on immobilization of metal mixtures for risk reduction in sites affected by mining legacy in our partner communities on Navajo Nation and the Pueblo of Laguna. The motivation of this supplement is to support Taylor Busch, a graduate student of Navajo descent who will synergize the current research in EP1 (focused on metal immobilization of metal mixtures), to explore new approaches that use plant-fungi symbiosis for the remediation of toxic metal mixtures. Taylor Busch will investigate the role of fungi on the accumulation of U and As in plants. We will build from initial work conducted by Taylor Busch who has collaborated with our Center as an undergraduate researcher, using the native grass, Bouteloua gracilis (blue grama) and fungi that have already been isolated from the contaminated areas in our partner community of Laguna Pueblo. We will conduct culture experiments to evaluate uptake of U and As integrating aqueous chemistry, microscopy, and spectroscopy tools for elemental composition and metal speciation in fungi and plants. Taylor Busch will be mentored by Dr. José Cerrato, who is the lead investigator for EP1 and has a strong track-record with under-represented students. Eliane El Hayek will serve as a Co-mentor and will facilitate the integration with biomedical and environmental projects of the UNM METALS SRC. The collaboration with Jennifer Rudgers who is an expert in fungi ecology will be an invaluable asset to this supplement given that Taylor Busch has already been working with her as an undergraduate researcher. The Administrative Core, Translation Core, Training Core and Community Engagement Core will support the mentoring of Taylor Busch and provide invaluable opportunities for professional development working with our partner communities. The proposed activities for this supplement can be feasibly completed by March 31, 2022 which is the end date of Phase of the UNM METALS SRC. We will look for other funding opportunities for Taylor Busch to continue working on this project beyond the end of Phase 1 of the UNM METALS SRC so Taylor Busch can obtain her Master of Science (MS) degree.

项目概要 本 SRP 研究的目标 补充 促进健康相关的多样性 研究旨在补充新墨西哥大学金属研究第一阶段的工作 西南部部落土地的暴露和毒性评估 (UNM METALS) 超级基金基础研究中心（SRC）环境项目1（EP1） EP1的重点是。 关于固定金属混合物以减少受采矿遗留影响的地点的风险 纳瓦霍族和拉古纳普韦布洛的合作伙伴社区 这样做的动机。 补充资金是为了支持纳瓦霍血统的研究生泰勒·布希（Taylor Busch），他将协同作用 目前EP1的研究（重点是金属混合物的金属固定化），探索新的 利用植物-真菌共生来修复有毒金属混合物的方法。 Busch 将研究真菌对植物中 U 和 As 积累的作用。 来自泰勒·布希 (Taylor Busch) 进行的最初工作，他与我们中心合作，作为 本科生研究员，使用本地草、Bouteloua gracilis（蓝色格拉玛）和真菌 已经与我们合作伙伴社区的受污染地区隔离 我们将进行培养实验来评估 U 和 As 的整合吸收。 用于元素成分和金属的水化学、显微镜和光谱工具 真菌和植物中的物种形成。 Taylor Busch 将接受 EP1 首席研究员 José Cerrato 博士的指导 并在代表人数不足的学生中拥有良好的记录，Eliane El Hayek 将担任该项目的校长。 共同导师并将促进与生物医学和环境项目的整合 UNM METALS SRC 与真菌生态学专家 Jennifer Rudgers 的合作。 鉴于泰勒·布希 (Taylor Busch) 已经在工作，这将是本增刊的无价资产 与她一起担任本科研究员的行政核心、翻译核心、培训。 核心和社区参与核心将支持泰勒·布希的指导并提供 与我们的合作伙伴社区合作提供宝贵的职业发展机会。 本补充计划的拟议活动可以在 2022 年 3 月 31 日之前完成，其中 是 UNM METALS SRC 阶段的结束日期，我们将寻找其他融资机会。 泰勒·布希 (Taylor Busch) 在 UNM 第一阶段结束后继续从事该项目 METALS SRC 使 Taylor Busch 能够获得理学硕士学位 (MS)。