National Drug Early Warning System (NDEWS) Administrative Supplement - Poison Control

国家毒品早期预警系统 (NDEWS) 行政补充文件 - 毒物控制

• 批准号: 10382615
• 负责人: Linda B. Cottler
• 金额: $ 10.75万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10382615
• 关键词: Administrative Supplement; American; Back; COVID-19; Censuses; Cessation of life; Chemicals; Cocaine; Collection; Communities; Data; Data Collection; Data Set; Databases; Drug Administration Routes; Drug Exposure; Drug Monitoring; Drug usage; Early Diagnosis; Electronic Health Record; Ensure; Epidemiology; Exposure to; Feedback; Fentanyl; Future; Geography; Healthcare; Hour; Individual; Information Systems; Methamphetamine; Minor; Monitor; Morbidity - disease rate; National Institute of Drug Abuse; Parents; Patients; Pattern; Peer Review; Pharmaceutical Preparations; Plants; Poison; Poison Control Centers; Prevention; Process; Public Health; Publications; Reporting; Research; Scientist; Sentinel; Severities; Signal Transduction; Site; Source; Suicide attempt; Surveillance Methods; System; Time; Time trend; addiction; age group; analog; base; bath salts; epidemiology study; exposed human population; heroin use; mortality; novel; outreach; parent grant; poison control; prospective; response; sex; social media; statistics; substance use; surveillance data; synthetic cannabinoid; trend

SUMMARY OF PARENT GRANT AND PROPOSED SUPPLEMENT Parent Study: Through our parent U01, our National Drug Early Warning System (NDEWS) Coordinating Center aims to provide NIDA and the field with the most timely, salient, and valuable information on emerging substance use trends. By expanding data collection to include both former NDEWS sentinel sites as well as former Community Epidemiology Workgroup (CEWG) sites, and by incorporating novel surveillance methods to ensure early detection of signals of new psychoactive substances and known substances, our Early Warning Network extends geographic representation and provides a more complete picture of the size, direction, and depth of substance use patterns in all US Census regions. We use novel surveillance methods to ensure early detection of signals indicating emerging drug trends and harmonize surveillance data across sentinel and CEWG sites. We will also conduct on-the-ground epidemiologic investigations on topics of immediate crisis or need in order to provide functional feedback to impacted communities towards optimizing current and future response, and we will disseminate results rapidly to the scientific community and the public alike. Proposed Supplement: As an Early Warning System, NDEWS must be on the forefront of new trends in drug use, and drug-related morbidity and mortality. There is a lack of current or recent drug-related mortality data because processing of death information is lagged by months. Poison Control data, however, would allow us to detect emerging trends in both poisonings and deaths (‘exposures’) related to drug use in 48 states in almost real time. We will obtain Poison Control data from the Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS) System and examine trends in exposures related to use of heroin, fentanyl and its analogs, cocaine, methamphetamine, and various new psychoactive substances, by month, for 12 months, to alert scientists and the public about trends in hotspots in near real time. Rates will be based on sex, Census age group, severity of effects (i.e., none, minor, moderate, major, death), route of drug administration, intent (e.g., intentional misuse, suicide attempt), and co-drug use. For Aim 1, we will acquire Poison Control data, monthly, and examine current trends in drug-related exposures and deaths, in near-real-time. For Aim 2, we will obtain data going as far back as 2015 and examine trends retrospectively. For Aim 3, we will rapidly disseminate statistics (monthly) on drug-related exposures to the scientific community and to the public through NDEWS listservs and media outreach and disseminate retrospective trends through peer-reviewed publications. We believe this is an extraordinary opportunity to quickly and frequently analyze drug exposure data and disseminate findings.

父母赠款和拟议补充的摘要 家长研究：通过我们的父母U01，我们的国家药物预警系统（NDEWS）协调 中心旨在为NIDA和该领域提供有关新兴的最及时，最显着和有价值的信息 物质使用趋势。通过扩展数据收集到包括以前的NDEWS哨兵站点以及 前社区流行病学工作组（CEWG）站点，并通过合并的新型监视方法 为了确保早期发现新的精神活性物质和已知物质的信号，我们的预警 网络扩展了地理表示，并提供了更完整的大小，方向和 美国所有人口普查区域中物质使用模式的深度。我们使用新颖的监视方法来确保尽早 检测指示新兴药物趋势并统一跨前哨的监视数据的信号检测 CEWG站点。我们还将对直接危机或 为了向受影响社区提供功能反馈以优化当前和未来 回应，我们将迅速向科学界和公众传播结果。 拟议的补充：作为预警系统，NDEWS必须处于毒品新趋势的最前沿 使用以及与药物有关的发病率和死亡率。缺乏当前或最近与药物有关的死亡率数据 因为死亡信息的处理滞后数月。但是，毒物控制数据将使我们能够 检测中毒和死亡的新兴趋势（“暴露”）几乎在48个州 即时的。我们将从研究的滥用，转移和成瘾有关 监视（雷达）系统，并检查与海洛因，芬太尼及其使用有关的暴露趋势 类似于类似物，可卡因，甲基苯丙胺和各种新的精神活性物质，按月，持续12个月 向科学家和公众提醒人们几乎实时的热点趋势。费率将基于性别，人口普查 年龄组，影响的严重程度（即无，次要，中等，大，死亡），药物管理途径，意图 （例如，故意滥用，自杀企图）和共同药物使用。对于AIM 1，我们将获取毒物控制数据， 每月一次，并在近实时检查与药物有关的暴露和死亡的当前趋势。对于目标2，我们 将回顾到2015年的数据，并回顾性地检查趋势。对于AIM 3，我们将迅速 传播有关与毒品有关的科学界和公众暴露的统计数据（每月） 通过NDEWS列表服务和媒体宣传，并通过同行评审来传播回顾性趋势 出版物。我们认为，这是一个非凡的机会，可以快速和经常分析药物暴露 数据并传播发现。