National Drug Early Warning System Coordinating Center

国家毒品预警系统协调中心

• 批准号: 10579886
• 负责人: Linda B. Cottler
• 金额: $ 67.44万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10579886
• 关键词: Algorithms; Annual Reports; Anticonvulsants; Area; Artificial Intelligence; Attention; Authorization documentation; Bioinformatics; Cities; Cognitive; Collaborations; Communicable Diseases; Communities; Consensus; Data; Data Collection; Data Sources; Detection; Development; Diffusion of Innovation; Discipline; Drug usage; Early Diagnosis; Education; Ensure; Epidemiology; Feedback; Florida; Forensic Medicine; Funding; Future; Geography; Hair; Health; International; Intervention; Location; Machine Learning; Maps; Measures; Methodology; Methods; Modeling; National Institute of Drug Abuse; New York; Notification; Outcome; Overdose; Peer Review; Perception; Persons; Pharmaceutical Preparations; Population Surveillance; Prevention strategy; Price; Process; Psychiatry; Public Health; Publications; Qualifying; Quality Control; Reporting; Research; Research Personnel; Robotics; Rural; Science; Scientist; Sentinel Surveillance; Signal Transduction; Site; Sociology; Source; Standardization; Strategic Planning; Surveillance Methods; System; Techniques; Testing; Time; Toxicology; Training; U-Series Cooperative Agreements; Universities; Update; Visualization; Work; addiction; authority; dashboard; epidemiology study; evidence base; future epidemic; innovation; meetings; mortality; next generation; novel; prevent epidemics; response; social media; substance use; substance user; suburb; surveillance data; theories; trend; virtual; web site; webinar

PROJECT SUMMARY/ABSTRACT Our team enthusiastically submits this proposal to be the next NDEWS Coordinating Center (CC) in response to RFA DA-20-016. The CC is spearheaded by the Cottler Lab (Epidemiology), with investigators from University of Florida's Center for Addiction Research & Education (Nixon, Goldberger, Striley), the Palamar Lab at New York University and the Machine Perception and Cognitive Robotics Lab-Barenholtz) at Florida Atlantic University. Our CC will maintain strong sentinel surveillance efforts while expanding our Early Warning Network sites, adding leading edge indicators that extend beyond lagged city-level data. We will extend the work of NIDA-funded researchers, while harmonizing and analyzing data, with timely and systematic notifications. The new NDEWS CC will work to seamlessly transition on-going efforts, advance methods and approaches, establish and engage a Scientific Advisory Group (SAG), and collaborate with all consortium components to accomplish these Specific Aims: 1) Provide an Early Warning Network of 12 NDEWS sites and 6 Community Epidemiology Workgroup sites for ongoing surveillance of urban, rural, and suburban areas; 2) Utilize established and new key community-level indicators for ongoing surveillance to assess trends in availability, use, and consequences of NPS and known substances, standardized across all sites to facilitate cross-site analyses; 3) Incorporate and leverage novel surveillance methods to ensure early detection of signals of NPS and emerging drug trends, including data from DanceSafe “drug checkers,” Rapid Street Reporting (RSR) with hair testing for NPS exposure, the implementation of a virtual HealthStreet substance user network, and development of an innovative machine learning approach to detect emergence of NPS in real-time through drug retailers (including the “darknet”) and social media platforms; 4) Harmonize standardized indicator definitions for all incoming surveillance data with the input of NIDA, the SAG, and Early Warning Network experts; facilitate cross-site comparability of data; manage quality control; organize, coordinate, and summarize data, and provide organizational and logistical support; 5) Disseminate findings quickly via dashboards modeled after Florida Drug-related Outcomes Surveillance and Tracking System (FROST); push notifications for regular updates and alerts; webinars; virtual Our Community Our Health Town Hall meetings; and traditionally through official reports, peer-reviewed publications, media, and annual reporting at CPDD, and elsewhere; 6) Conduct on-the-ground epidemiologic investigations on topics of immediate crisis or need; 7) Provide operational, administrative, and logistical support to the enterprise and NIDA; and 8) Train the next generation of scientists in NDEWS methodology. NDEWS has unrealized potential, and with this funding, we will transform the culture so that NDEWS is NIDA's and the field's go-to source for drug trends in the US. It will provide evidence-based prevention and intervention strategies to eventually reduce the harmful effects of substance use around the world.

项目概要/摘要 作为回应，我们的团队热情地提交了成为下一个 NDEWS 协调中心 (CC) 的提案 RFA DA-20-016 CC 由 Cottler 实验室（流行病学）牵头，调查人员来自 佛罗里达大学成瘾研究与教育中心（Nixon、Goldberger、Striley），帕拉马 纽约大学实验室和佛罗里达州机器感知和认知机器人实验室（Barenholtz） 大西洋大学我们的 CC 将保持强有力的哨点监视工作，同时扩大我们的早期预警。 网络站点，添加超越滞后城市级数据的领先指标。 NIDA 资助的研究人员的工作，同时及时和系统地协调和分析数据 新的 NDEWS CC 将致力于无缝过渡正在进行的工作、推进方法和 方法，建立并聘请科学咨询小组 (SAG)，并与所有联盟合作 实现这些具体目标的组件： 1) 提供由 12 个 NDEWS 站点组成的早期预警网络 6 个社区流行病学工作组站点，用于对城市、农村和郊区进行持续监测2) 利用现有的和新的关键社区级指标进行持续监测，以评估趋势 NPS 和已知物质的可用性、使用和后果，在所有地点进行标准化，以促进 跨站点分析；3) 纳入并利用新颖的监测方法，以确保及早发现 NPS 信号和新兴药物趋势，包括来自 DanceSafe“药物检查员”、Rapid Street 的数据 通过头发检测 NPS 暴露的报告 (RSR)，实施虚拟 HealthStreet 物质 用户网络，以及开发创新的机器学习方法来检测 NPS 的出现 通过药品零售商（包括“暗网”）和社交媒体平台进行实时协调； 根据 NIDA、SAG 和 Early 的输入，对所有传入监测数据进行标准化指标定义 警告网络专家；促进数据的跨站点可比性；管理质量控制； 协调和汇总数据，并提供组织和后勤支持；5）传播调查结果； 通过仿照佛罗里达州毒品相关结果监测和跟踪系统的仪表板快速进行 (FROST)；定期更新和警报的推送通知；虚拟我们的社区我们的健康小镇； 大厅会议；传统上通过官方报告、同行评审出版物、媒体和年度会议 在 CPDD 和其他地方进行报告； 6) 就以下主题进行实地流行病学调查： 7) 为企业提供运营、行政和后勤支持； NIDA；8) 培训下一代 NDEWS 科学家。 NDEWS 具有未实现的潜力，利用这笔资金，我们将转变文化，使 NDEWS 成为现实 NIDA 和该领域的美国药物趋势的首选来源它将提供基于证据的预防和治疗。 最终减少世界各地物质使用有害影响的干预策略。