Support of Yerkes National Primate Research Center

耶基斯国家灵长类研究中心的支持

• 批准号: 10190517
• 负责人: JONATHAN S LEWIN
• 金额: $ 47.62万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-16 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10190517
• 关键词: Animal Housing; Basic Science; Behavioral; Behavioral Research; Biocompatible Materials; Biology; Biomedical Research; Breeding; Collaborations; Communities; Consultations; Development; Discipline; Ensure; Environment; Faculty; Funding; Genetic; Goals; Grant; Guidelines; Health; Housing; Human; Immunology; Infrastructure; International; Knowledge; Laboratory Research; Mental disorders; Microbiology; Mission; Neuropharmacology; Neurosciences; Pathology; Personal Satisfaction; Postdoctoral Fellow; Primates; Process; Publications; Reporting; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Role; Scientist; Services; Social Behavior; Strategic Planning; Translational Research; Transplantation; United States National Institutes of Health; Universities; Visit; animal facility; animal resource; base; cognitive neuroscience; data resource; graduate student; improved; innovation; laboratory facility; medical specialties; member; multidisciplinary; nervous system disorder; nonhuman primate; programs; training opportunity; undergraduate student

OVERALL – SUMMARY/ABSTRACT This application seeks five years of continued support for the P51 Base Grant (OD 011132) for the Yerkes National Primate Research Center of Emory University. The overarching goals of Yerkes are to conduct a research program focused on scientific problems relevant to human health and the NIH mission by providing resource infrastructure and expertise in appropriate scientific and veterinary specialties and to ensure the Center's ability to serve as a resource to Core Scientists, as well as to scientists regionally, nationally and internationally. During the current reporting period (5/1/2011 to present), the Yerkes Center has recorded remarkable progress, as evidenced by numerous (>790) publications, construction of new animal facilities, including a state-of-the-art transplantation and ABSL3 facility, and progressive expansion of its research funding base, even in the era of an extremely competitive NIH funding environment. In addition, the Yerkes Primate Center has maintained outstanding core research programs and provided resources and services to a broad multidisciplinary network of affiliate and collaborative investigators throughout the region and nation. These research programs, which involve the use of a variety of nonhuman primate species, are directed primarily toward four major research disciplines, representing the research divisions within the Yerkes Center: 1) Microbiology and Immunology; 2) Developmental and Cognitive Neuroscience, 3) Neuropharmacology and Neurologic Diseases and 4) Behavioral Neuroscience and Psychiatric Disorders. Also, through the Divisions of Animal Resources and Pathology, Yerkes provides support for outside investigators conducting research at the Yerkes Center, consistent with our ORIP-mandated role as a regional and national resource. Specific aims for the upcoming period of support include: 1) To carry out basic and translational research using nonhuman primates to expand knowledge, develop improved treatments, and advance cures that will benefit humanity; 2) To provide regional and national resources for data, consultative expertise, biologic materials, and specialized facilities useful in supporting nonhuman primate research; 3) To study basic nonhuman primate biology and improve nonhuman primate breeding, husbandry and genetic characterization to better serve the biomedical research community; and 4) To provide research and training opportunities involving nonhuman primates to graduate and undergraduate students, postdoctoral fellows, visiting scientists and faculty members. The pursuit of these aims will enhance the Center's ability to serve as an enabling resource to Core and Affiliate Scientists for the conduct of nonhuman primate research, all for the ultimate goal of advancing human health.

总体 - 摘要/摘要 该申请为Yerkes提供了五年的持续支持（OD 011132） 埃默里大学国家灵长类动物研究中心。 Yerkes的总体目标是进行 研究计划的重点是与人类健康和NIH任务相关的科学问题 资源基础架构和适当科学和兽医专业的专业知识，并确保 中心有能力作为核心科学家的资源，以及科学家在地区，全国和 国际。在当前的报告期（2011年5月1日到现在），Yerkes中心已记录 众多（> 790）出版物，新动物设施的建设证明了这一点， 包括最先进的移植和ABSL3设施，以及逐步扩展其研究 资金基础，即使在竞争激烈的NIH资助环境的时代。另外，Yerkes 灵长类动物中心一直保持着杰出的核心研究计划，并为 整个地区和国家的会员和合作调查员的广泛多学科网络。 这些研究计划涉及使用各种非人类灵长类动物，并被指向 首先是四个主要的研究学科，代表耶克斯中心内的研究部门： 1）微生物学和免疫学； 2）发展和认知神经科学，3）神经药理和 神经系统疾病和4）行为神经科学和精神疾病。而且，通过 动物资源和病理学，Yerkes为外部调查人员提供了支持 Yerkes Center，与我们作为区域和国家资源的Orip规定角色一致。具体目标 即将到来的支持时期包括：1）使用非人类进行基本和翻译的研究 灵长类动物扩大知识，发展改进的治疗方法和进步可以使人类受益的治疗方法； 2） 为数据，咨询专业知识，生物材料和专业提供区域和国家资源 设施有助于支持非人类灵长类动物研究； 3）研究基本的非人类灵长类动物生物学和 改善非人类的灵长类动物育种，饲养和遗传特征，以更好地为生物医学服务 研究社区； 4）提供涉及非人类隐私的研究和培训机会 研究生和本科生，博士后研究员，来访的科学家和教职员工。这 追求这些目标将增强中心作为核心和分支机构的促进资源的能力 进行非人类灵长类动物研究的科学家，所有这些都是为了促进人类健康的最终目标。