Support of Yerkes National Primate Research Center

耶基斯国家灵长类研究中心的支持

基本信息

批准号：
10190517
负责人：
JONATHAN S LEWIN
金额：
$ 47.62万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-06-16 至 2021-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10190517
关键词：
Animal Housing Basic Science Behavioral Behavioral Research Biocompatible Materials Biology Biomedical Research Breeding Collaborations Communities Consultations Development Discipline Ensure Environment Faculty Funding Genetic Goals Grant Guidelines Health Housing Human Immunology Infrastructure International Knowledge Laboratory Research Mental disorders Microbiology Mission Neuropharmacology Neurosciences Pathology Personal Satisfaction Postdoctoral Fellow Primates Process Publications Reporting Research Research Infrastructure Research Personnel Research Training Resources Role Scientist Services Social Behavior Strategic Planning Translational Research Transplantation United States National Institutes of Health Universities Visit animal facility animal resource base cognitive neuroscience data resource graduate student improved innovation laboratory facility medical specialties member multidisciplinary nervous system disorder nonhuman primate programs training opportunity undergraduate student

项目摘要

OVERALL – SUMMARY/ABSTRACT This application seeks five years of continued support for the P51 Base Grant (OD 011132) for the Yerkes National Primate Research Center of Emory University. The overarching goals of Yerkes are to conduct a research program focused on scientific problems relevant to human health and the NIH mission by providing resource infrastructure and expertise in appropriate scientific and veterinary specialties and to ensure the Center's ability to serve as a resource to Core Scientists, as well as to scientists regionally, nationally and internationally. During the current reporting period (5/1/2011 to present), the Yerkes Center has recorded remarkable progress, as evidenced by numerous (>790) publications, construction of new animal facilities, including a state-of-the-art transplantation and ABSL3 facility, and progressive expansion of its research funding base, even in the era of an extremely competitive NIH funding environment. In addition, the Yerkes Primate Center has maintained outstanding core research programs and provided resources and services to a broad multidisciplinary network of affiliate and collaborative investigators throughout the region and nation. These research programs, which involve the use of a variety of nonhuman primate species, are directed primarily toward four major research disciplines, representing the research divisions within the Yerkes Center: 1) Microbiology and Immunology; 2) Developmental and Cognitive Neuroscience, 3) Neuropharmacology and Neurologic Diseases and 4) Behavioral Neuroscience and Psychiatric Disorders. Also, through the Divisions of Animal Resources and Pathology, Yerkes provides support for outside investigators conducting research at the Yerkes Center, consistent with our ORIP-mandated role as a regional and national resource. Specific aims for the upcoming period of support include: 1) To carry out basic and translational research using nonhuman primates to expand knowledge, develop improved treatments, and advance cures that will benefit humanity; 2) To provide regional and national resources for data, consultative expertise, biologic materials, and specialized facilities useful in supporting nonhuman primate research; 3) To study basic nonhuman primate biology and improve nonhuman primate breeding, husbandry and genetic characterization to better serve the biomedical research community; and 4) To provide research and training opportunities involving nonhuman primates to graduate and undergraduate students, postdoctoral fellows, visiting scientists and faculty members. The pursuit of these aims will enhance the Center's ability to serve as an enabling resource to Core and Affiliate Scientists for the conduct of nonhuman primate research, all for the ultimate goal of advancing human health.

总体 - 摘要/摘要该申请为Yerkes提供了五年的持续支持（OD 011132）埃默里大学的国家灵长类研究中心。研究计划的重点是与人类健康和NIH任务相关的科学问题资源基础架构和专业知识在适当的科学和兽医专业方面，并确保您的位置 Central有能力充当核心科学家的资源，即科学家，全国和国家。在当前的报告期（2011年5月1日）中，Yerkes中心已记录众多（> 790）出版物，新动物设施的约束证明了这一点的显着进步，包含一个州立的移植和ABSL3设施，以及逐步扩大其研究资金基础，即使在竞争激烈的NIH资金环境中也是如此。灵长类动物中心已经维持了出色的核心研究计划，并为整个国家的跨学科和合作调查人员的广泛多学科网络。这些研究计划涉及使用各种非人类灵长类动物，并被指向主要是四个主要的研究学科，代表耶克斯中心内的研究部门： 1）微生物学和免疫学； 2）发育和认知神经科学，3）神经系统疾病和4）行为神经科学和精神疾病。动物资源和病理学，耶克斯为外部调查人员提供支持 Yerkes Center，符合Orip规定的角色，作为Area和National Resorce的目标即将到来的宣传时期包括：1）使用非人类进行基础和转化研究提高知识，改善治疗方法的灵长类动物，并促进将有益于人类的治疗方法；提供区域和国家资源以获取数据，咨询专业知识，生物材料和专业的资源用于支持非人类灵长类动物研究的设施； 3）改善非人类的灵长类动物育种，饲养和遗传特征，以更好地为生物医学服务研究社区； 4）提供研究和培训机会，非人类灵长类动物研究生和地下学生，博士后研究员，访问科学家和fascalty成员追求目标将增强中心作为成为核心核心核心资源的核心资源非人类灵长类动物研究的科学家，所有这些都是为了促进人类健康的最终目标。