MR GUIDED THERMAL ABLATION OF ABDOMINAL TUMORS

MR 引导腹部肿瘤热消融

• 批准号: 6276530
• 负责人: JONATHAN S LEWIN
• 金额: $ 1.83万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6276530
• 关键词: abdomen neoplasm; clinical research; human subject; human therapy evaluation; magnetic resonance imaging; metastasis; neoplasm /cancer thermotherapy

The objectives of this trial are: to describe the safety of Magnetic Resonance (MR) guided thermal ablation of soft tissue metastases and to describe the fraction of tumor necrosis that can be generated within tumors through thermal ablation using a radiofrequency (RF) generator as the heat source. Patients are only those with solid tumors that have failed intervention with standard measures or those for which systemic therapy was considered ineffective. Patients must not be candidates for surgical resection. There have been eight patients treated (11 enrollments). Three patients were enrolled for ablation of different lesions. To date one subject achieved a complete response, five enrollments had stable disease, three developed progressive disease, one patient was cancelled and the last has not been analyzed.

该试验的目的是： 描述 Magnetic 的安全性 共振 (MR) 引导软组织转移热消融 描述可在内部产生的肿瘤坏死部分 使用射频 (RF) 发生器通过热消融治疗肿瘤 作为热源。 患者仅指患有实体瘤且患有以下疾病的患者： 标准措施或系统性措施的干预失败 治疗被认为无效。患者不得成为候选者 手术切除。 已有 8 名患者接受治疗（11 名患者入组）。 三个病人 被登记用于不同病变的消融。 迄今为止一主题 达到完全缓解，五名入组患者病情稳定， 三名患者出现进展性疾病，一名患者被取消， 最后没有分析。