MR GUIDED THERMAL ABLATION OF ABDOMINAL TUMORS

MR 引导腹部肿瘤热消融

• 批准号: 6115296
• 负责人: JONATHAN S LEWIN
• 金额: $ 1.92万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6115296
• 关键词: abdomen neoplasm; clinical research; human subject; human therapy evaluation; magnetic resonance imaging; metastasis; neoplasm /cancer thermotherapy

The objectives of this trial are: to describe the safety of Magnetic Resonance (MR) guided thermal ablation of soft tissue metastases and to describe the fraction of tumor necrosis that can be generated within tumors through thermal ablation using a radiofrequency (RF) generator as the heat source. Patients are only those with solid tumors that have failed intervention with standard measures or those for which systemic therapy was considered ineffective. Patients must not be candidates for surgical resection. There have been eight patients treated (11 enrollments). Three patients were enrolled for ablation of different lesions. To date one subject achieved a complete response, five enrollments had stable disease, three developed progressive disease, one patient was cancelled and the last has not been analyzed. This trial continues to accrue patients.

该试验的目的是：描述磁共振（MR）指导的软组织转移的热消融，并描述可以使用放射性消融（RF）发电机作为肿瘤中产生的肿瘤坏死的比例。热源。 患者只有那些患有标准措施干预措施或全身治疗无效的患者。 患者不能成为手术切除的候选者。有8例接受治疗的患者（11名入学人数）。 三名患者被纳入不同的病变。 迄今为止，一名受试者达到了完全的反应，五名入学率患有稳定的疾病，三种发育的进行性疾病，一名患者被取消，最后一名尚未分析。 该试验继续累积患者。