RCMI@Morgan: Center for Urban Health Disparities Research and Innovation

RCMI@摩根：城市健康差异研究与创新中心

• 批准号: 10113382
• 负责人: JAMES M WACHIRA
• 金额: $ 52.14万
• 依托单位: MORGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-31 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10113382
• 关键词: Address; Animal Experimentation; Animal Housing; Animal Testing; Animals; Area; Arts; Baltimore; Basic Science; Behavioral Sciences; Bioinformatics; Biology; Biomedical Research; Biometry; Cardiovascular Diseases; Communicable Diseases; Community Health; Complex; Computers and Advanced Instrumentation; Consultations; Core Facility; Data; Data Analyses; Decision Making; Diabetes Mellitus; Disease; Economic Development; Educational workshop; Engineering; Ensure; Environment; Faculty; Fee Schedules; Flow Cytometry; Funding; Future; Genes; Genetic; Genomics; Health; Health Policy; Health Promotion; Histology; Human Resources; Infrastructure; Institutes; Interdisciplinary Study; Laboratories; Laboratory Animals; Lead; Leadership; Maintenance; Molecular Analysis; Molecular and Cellular Biology; Operative Surgical Procedures; Outcome; Pathology; Persons; Pilot Projects; Psychology; Public Health; Public Health Informatics; Publications; Reporting; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Role; Schools; Science; Services; Site; Social Interaction; Social Work; Structure; Students; Training; Training Programs; Training and Education; United States National Institutes of Health; Universities; Update; Veterinarians; Work; addiction; base; behavioral study; college; community involvement; computing resources; experimental study; food security; health disparity; health inequalities; innovation; instrumentation; interest; meetings; member; molecular imaging; multidisciplinary; nanomaterials; new technology; notch protein; operation; outreach; research and development; research facility; therapy development; tool; urban health disparities; urban setting

Project Summary Health disparities are attributable to complex diseases that involve the interactions of social, environmental, and genetic factors. A better understanding of the mechanisms of the diseases and the development of interventions requires state-of-the-art research facilities that support top notch, multidisciplinary research and the involvement of the community. The Research Infrastructure Core (RIC) will provide the administrative structure, instrumentation, and expertise needed to perform multidisciplinary biomedical and health disparities research in the urban setting of Baltimore. Based on the current and future research needs at Morgan State University, three Core Research Facilities (CRFs) will be established or enhanced: 1) Animal Research Core (ARC); 2. Molecular and Cellular Biology Research Core Laboratory (MCB); and 3. Biostatistics and Bioinformatics Support Unit (BBSU). To meet the needs of both behavioral and basic science researchers, the ARC will consist of two separate sites. It will be managed by a faculty Co-Lead and a Core Manager. It will provide animal housing and testing rooms and advanced instrumentation for histology/pathology, surgery, and behavioral studies. A veterinary doctor from Johns Hopkins University will serve as the ARC's to oversee the health of research animals. The MCB will comprise of multiple laboratories in the Dixon Research Center and it will be managed by a Co-Lead and a Core Manager. It will provide support for genomics, flow cytometry, molecular imaging, molecular analyses, nanomaterials research, and other cutting-edge experiments. The BBSU will be managed by a faculty Co-Lead who will be assisted by a Faculty Bioinformatician. It will offer statistical and bioinformatics consultation and computational resources to researchers. The BBSU will be housed in an RCMI office area in Portage. The three CRFs will conduct outreach, regular training workshops, and will promote the dissemination of research findings through publications and by assisting users with data analyses. The CRFs will belong to the University as shared facilities for use by any MSU researcher. An Oversight Committee consisting of the Vice President for Research and Economic Development (DRED) and the deans of the schools (Engineering, Sciences, and Social Work) and colleges (Community Health and Policy and Liberal Arts) of participating faculty will provide guidance to the PI and RIC Lead on matters relating to major purchases, space allocations, facilities, and personnel changes. It will advise the president and provost on the biomedical research needs of the university and facilitate the sustainability of the CRFs beyond the RCMI funding period. The PI will discuss CRFs' operations with the Lead and Co-Leads regularly and the Lead and Co-Leads will meet monthly and as necessary to review progress towards meeting the objectives of the RIC, resolve any problems, and to strategize on how to enhance and sustain research in the different areas of interest. The resources, training programs, and outreach efforts to faculty and other users will serve to entrench competitive research in health and health disparities at Morgan State University.

项目摘要 健康差异归因于涉及社会，环境和环境相互作用的复杂疾病 遗传因素。更好地理解疾病机制和干预措施的发展 需要最先进的研究设施，以支持一流的档位，多学科研究和参与 社区。研究基础设施核心（RIC）将提供行政结构， 仪器和专业知识需要进行多学科生物医学和健康差异研究 巴尔的摩的城市环境。根据摩根州立大学的当前和未来研究需求，三个 将建立或增强核心研究设施（CRF）：1）动物研究核心（ARC）； 2。分子 和细胞生物学研究核心实验室（MCB）；和3。生物统计学和生物信息学支持单位 （BBSU）。为了满足行为和基础科学研究人员的需求，弧线将由两个 单独的站点。它将由教师共同领导和核心经理管理。它将提供动物住房和 测试室和高级仪器，用于组织学/病理学，手术和行为研究。一个 约翰·霍普金斯大学的兽医医生将作为监督研究健康的弧线 动物。 MCB将由迪克森研究中心的多个实验室组成，并将管理 由共同领导和核心经理。它将为基因组学，流式细胞术，分子成像提供支持， 分子分析，纳米材料研究和其他尖端实验。 BBSU将被管理 由一位教师的领导者由一位教师生物信息学家协助。它将提供统计和生物信息学 向研究人员进行咨询和计算资源。 BBSU将安置在RCMI办公区域 端口。这三个CRF将进行外展，定期培训研讨会，并将促进传播 通过出版物并通过帮助用户进行数据分析的研究结果。 CRF将属于 大学作为共享设施，用于任何MSU研究人员使用。一个由副人组成的监督委员会 研究与经济发展总裁（DRED）和学校的院长（工程， 科学，社会工作）以及参与教师 将为PI和RIC的领导提供指导，内容涉及大量购买，空间分配，设施， 和人员改变。它将向总统和教务长提供有关生物医学研究需求的建议 大学并促进CRF的可持续性，超过RCMI资助期。 PI将讨论CRFS 定期与领先者和共同领导者的行动，铅和共同领导者每月开会，AS 需要审查实现RIC目标，解决任何问题并制定战略目标的进度所必需的进度 关于如何增强和维持在不同感兴趣领域的研究。资源，培训计划， 以及向教职用户和其他用户的推广工作将为健康与健康方面的竞争性研究奠定 摩根州立大学的差异。