3-dimensional Analysis for Conduction Blocks of the Spinal Cord with Multi-channel Superconducting Quantum Interference Device.

利用多通道超导量子干涉装置对脊髓传导块进行三维分析。

• 批准号: 11557109
• 负责人: FUJIMOTO Yoshinori
• 金额: $ 8.58万
• 依托单位: Hiroshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11557109/
• 关键词: Spinal Cord Magnetic Field; Superconduction Quantum Interference Device; SQUID; Spinal Cord

The magnetic filed measurement of the spinal cord has theoretical advantages of high spatial resolution compared with the conventional electric potential measurement. The purpose of this study was to measure the magnetic field of the spinal cord and to examine three-dimensional conduction blocks of the cord with superconduction quantum interference device (SQUID). The highly sensitive SQUID was designed for detection of the fine magnetic fields from the spinal cord. A gradiometer system with two SQUID coils was produced for the study. Also a small shield room was designed and produced to intercept outside magnetic noise and the SQUID system were placed within the shield room. An operation table was placed on a movable plastic gantry. The sciatic nerve of a cat was stimulated electrically and evoked magnetic fields produced in the spinal cord were measured at the thoracic and the lumbar spine. Evoked magnetic fields at the upper lumbar spine could be measured by sciatic nerve stimulation. The magnetic field measurement with the SQUID could diagnose the conduction blocks and was useful for the analysis of the spinal cord function.

与常规的电势测量相比，脊髓的磁性测量具有高空间分辨率的理论优势。这项研究的目的是测量脊髓的磁场，并使用超导量量子干扰装置（Squid）检查绳索的三维传导块。高度敏感的鱿鱼设计用于检测脊髓的细磁场。为研究生产了带有两个鱿鱼线圈的梯度计系统。还设计和生产了一个小型盾牌室，以拦截外部磁噪声，并将鱿鱼系统放置在盾牌室内。将操作表放在可移动的塑料龙门上。刺激猫的坐骨神经，并在胸椎和腰椎测量脊髓中产生的磁场。可以通过坐骨神经刺激来测量上腰椎的诱发磁场。使用鱿鱼的磁场测量可以诊断传导块，对于分析脊髓功能很有用。

项目成果

藤本吉範: "脊髄髄内腫瘍に対する脊髄機能モニタリング"脊髄電気診断学 別冊. 21・1. 68-71 (1999)

藤本义德：“髓内肿瘤的脊髓功能监测”《脊髓电诊断特卷》21・1（1999）。

藤本吉範: "脊髄疾患に対するモニタリングの有用性-各種誘発電位を用いて-"中部整災誌. 42. 1253-1254 (1999)

Yoshinori Fujimoto：“监测脊髓疾病的有用性 - 使用各种诱发电位 -”中部灾害管理杂志 42. 1253-1254 (1999)。