A Study on Mass Culture of Plankton Living in Extreme Environments and their Production of Useful Compounds.

极端环境下浮游生物的大规模培养及其有用化合物的生产研究。

• 批准号: 62480068
• 负责人: YAMAGUCHI Katsumi
• 金额: $ 4.03万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62480068/
• 关键词: Extreme environment plankton; Mass culture; Goniodoma pseudogoniaulax; Dunaliella bardawil; Biologically active compound; Nitrogenous extractive component; ペプチド; Gonioloma pseuologonianlax; Oscillatoria sp-2; ポリエーテルマクロライド; Goniodomin A; エキス成分

The aim of the present project is to establish optimum conditions for massculture of phytoplankton living in extreme environments and to search for such useful substances as biologically active compounds and nitrogenous extractive componets produced by those plankton.1. More than 30 species of phytoplankton were collected and mass cultivated.2. Screening of biologically active compounds was carried out by means of the antimicrobial activity test and the inhibition test of development of fertilized echinderm eggs.3. A novel antifungal polyether macrolide, goniodomin A, was isolated from the dinoflagellate Goniodoma pseudogoniaulax living in the rock pool and its structure was determined on the basis of spectral data.4. Extractive nitrogenous constituents in the halotolerant green alga Dunaliella bardawil were analyzed. Approximately 45% of the constituents was accounted for by peptides, some of which showed inhibitory effects in the enzyme assay.

本项目的目的是建立生活在极端环境中的浮游植物大众的最佳条件，并寻找诸如生物活性化合物和硝基化合物和氮的提取组分等有用的物质。收集了30多种浮游植物并进行质量培养。2。通过抗菌活性测试和抑制受精的echinderm卵的发展进行生物活性化合物的筛选。3。从岩石池中的鞭毛藻藻虫蛋白瘤pseudogoniaulax中分离出一种新型的抗真菌性聚醚大花环促性腺素A，其结构是根据光谱数据确定的。4。分析了盐油绿色藻类dunaliella bardawil中的提取氮成分。大约45％的成分是由肽解释的，其中一些成分在酶测定中显示抑制作用。

项目成果

山口勝己: 日本水産学会誌. 54. 239-243 (1988)

Katsumi Yamaguchi：日本水产科学会杂志 54. 239-243 (1988)。

村上昌弘: 日本水産学会誌.

村上正宏：日本水产学会杂志。

Masahiro Murakami: "Screening of biologically active compounds in microalgae." Nippon Suisan Gakkaishi. 54. 1035-1039 (1988)

Masahiro Murakami：“微藻中生物活性化合物的筛选。”

村上昌弘: 日本水産学会誌. 54. 1035-01039 (1988)

村上正宏：日本水产学会杂志 54. 1035-01039 (1988)

村上昌弘: Terahedron Letters.

村上正宏：四面体字母。