NSF/FDA SIR: Safer (polymeric) batteries in medical devices and evolving regulatory framework

NSF/FDA SIR：医疗设备中更安​​全的（聚合物）电池和不断发展的监管框架

• 批准号: 2037835
• 负责人: Peter Kofinas
• 金额: $ 8.34万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2037835&HistoricalAwards=false
• 关键词: NSF; FDA; SIR; Safer; polymeric

Batteries play an important role in the overall function, reliability, and safety of many medical devices such as pacemakers, implantable cardioverter defibrillators, glucose monitoring devices, and wheelchairs. The insights gained in this one-year NSF/FDA Scholar-In-Residence fundamental research project will aid and inform the development of protocols that demonstrate safety and feasibility of polymer electrolytes for lithium batteries. Success of this project will help streamline the regulation of solid polymer electrolytes in medical devices as a safer alternative. In addition to the impacts on science, the project will also broadly impact engineering education, training students of different educational levels and from diverse backgrounds. Several initiatives are planned, including specific programs that assist in undergraduate and graduate education, graduate student mentoring, and training of high school students. The goal of this project is to better understand the electrochemical, transport, and safety properties of water-containing solid polymer electrolytes. A small amount of water acts as a super plasticizer of the polymer matrix and provides an alternative conduction pathway that significantly improves cation transport. Additionally, the inclusion of water is expected to have a significant impact on the safety of the resulting battery device. Specifically, the Investigator’s propose to study an aqueous solid polymer electrolyte (ASPE) consisting of varying amounts of polyacrylonitrile (PAN), water, and lithium salt as a model system to probe these questions. An investigation of these ASPEs will focus on determining how salt concentration, water concentration, and polymer molecular weight can affect ionic conductivity, cation transport, electrochemical stability, cell safety, and cell performance. Gaining insight into the water-dominant transport mechanism causing the enhanced electrochemical performance of the proposed ASPE systems will greatly benefit the design of the next generation of batteries for medical devices. Full cell devices will undergo safety testing that will help inform an emerging regulatory framework for assessing the safety of polymer electrolytes for use in medical devices.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

电池在许多医疗设备的总体功能，可靠性和安全性中起着重要作用，例如太空制造商，可植入的心脏逆转除颤器，葡萄糖监测设备和轮椅。这项为期一年的NSF/FDA居住基础研究项目中获得的见解将有助于并告知协议的开发，这些方案证明了聚合物电解质对锂电池的安全性和可行性。该项目的成功将有助于简化医疗设备中固体聚合物电解质的调节，这是一种更安全的选择。除了对科学的影响外，该项目还将广泛影响工程教育，培训不同教育水平和不同背景的学生。计划了几项举措，包括有助于本科和研究生教育的特定计划，研究生心理以及对高中生的培训。该项目的目的是更好地了解含水固体聚合物电解质的电化学，运输和安全性。少量水充当聚合物基质的超增塑剂，并提供了一种替代传导途径，可显着改善阳离子的运输。此外，预计将水的加入对所得电池设备的安全性有重大影响。具体而言，研究者提出的研究固体聚合物电解质（ASPE）由不同量的聚丙烯硝那烯（PAN），水和锂盐作为模型系统来探测这些问题。对这些ASPE的研究将集中于确定盐浓度，水浓度和聚合物分子量如何影响离子电导率，阳离子运输，电化学稳定性，细胞安全性和细胞性能。了解拟议的ASPE系统的电化学性能增强的水上性运输机制，将极大地有益于医疗设备下一代电池的设计。完整的电池设备将经过安全测试，这将有助于为紧急监管框架提供评估用于医疗设备中的聚合物电解质的安全性。该奖项反映了NSF的法定任务，并被认为是通过基金会的智力优点和更广泛影响标准的智力优点评估通过评估来获得的支持。

项目成果

Water Domain Enabled Transport in Polymer Electrolytes for Lithium-Ion Batteries

• DOI: 10.1021/acs.macromol.0c01960
• 发表时间: 2021-03
• 期刊: Macromolecules
• 影响因子: 5.5
• 作者: Matthew D. Widstrom;O. Borodin;K. Ludwig;Jesse E. Matthews;Sahana Bhattacharyya;Mounesha G Garaga