MRI: Acquisition of a 500 MHz Nuclear Magnetic Resonance Spectrometer for Research and Training at the University of Arizona

MRI：购买 500 MHz 核磁共振波谱仪用于亚利桑那大学的研究和培训

基本信息

批准号：
1920234
负责人：
Jon Njardarson
金额：
$ 50.08万
依托单位：
University of Arizona
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-01 至 2022-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1920234&HistoricalAwards=false
关键词：
MRI Acquisition 500 MHz Nuclear

项目摘要

This award is funded by the Major Research Instrumentation (MRI) and Chemical Instrumentation (CRIF) programs. Professor Jon Njardarson from University of Arizona and colleagues Wei Wang, Jeffrey Pyun, Douglas Loy and Elisa Tomat have acquired a 500 MHz NMR spectrometer. In general, NMR spectroscopy is one of the basic tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is an essential tool for chemists who are carrying out frontier research. A typical use by a chemist is to analyze the mixture from a reaction to determine the products. For example investigations to improve materials used in battery electrodes to increase their efficiency will involve following the products by varying the starting materials in a chemical reaction. The spectrometer is used in laboratory courses to train undergraduate students in this powerful tool. A sizable cohort are from underrepresented and underserved groups. The award is aimed at enhancing research and education at all levels. A variety of research projects are being investigated. One project explores new synthetic methods used to prepare natural products. Another investigation probes the engineering of ligand-based redox chemistry in metal complexes of linear oligopyrroles. Sustainable polymer chemistry through utilization of waste sulfur to afford a new class of sulfur-based polymers is being studied. Metallopolymer electrocatalysts for hydrogen production are the focus of an investigation. Pioneering investigations to construct nano-engineered, hybrid organic-inorganic materials based on organically bridged polysilsesquioxanes is a current on-going study.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要的研究工具（MRI）和化学仪器（CRIF）计划资助。来自亚利桑那大学的乔恩·恩贾尔森教授和王王，杰弗里·皮恩，道格拉斯·洛伊和埃莉莎·托马特（Elisa Tomat）的教授已获得了500 MHz NMR光谱仪。通常，NMR光谱是化学家可用于阐明分子结构的基本工具之一。它用于识别未知物质，以表征分子中原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行边境研究的化学家来说，访问最先进的NMR光谱仪是必不可少的工具。化学家的典型用途是分析反应中的混合物以确定产物。例如，通过在化学反应中改变起始材料来改变效率以提高电池电极以提高其效率的调查。光谱仪用于实验室课程中，以使用此功能强大的工具来培训本科生。相当大的队列来自代表性不足和服务不足的群体。该奖项旨在增强各级研究和教育。正在研究各种研究项目。一个项目探讨了用于准备天然产品的新合成方法。另一项研究探究了基于配体的氧化还原化学在线性寡吡咯的金属络合物中的工程。通过利用废物硫来提供一类新的基于硫的聚合物，正在研究可持续的聚合物化学。用于氢生产的金属聚合物电催化剂是研究的重点。建造基于有机桥接多桥的多义质盐的纳米设计的混合有机无机材料的开创性调查是当前正在进行的研究。该奖项反映了NSF的法定任务，并被认为是通过基金会的智力和更广泛的影响来评估的支持，并被认为是值得通过评估的支持。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Albumin Conjugates of Thiosemicarbazone and Imidazole-2-thione Prochelators: Iron Coordination and Antiproliferative Activity.

DOI：
10.1002/cmdc.202100278
发表时间：
2021-09-16
期刊：
ChemMedChem
影响因子：
3.4
作者：
Sung YS;Wu W;Ewbank MA;Utterback RD;Marty MT;Tomat E
通讯作者：
Tomat E

Multicenter interactions and ligand field effects in platinum( ii ) tripyrrindione radicals

铂( ii )三吡啶二酮自由基的多中心相互作用和配体场效应

DOI：
10.1039/d3dt00894k
发表时间：
2023
期刊：
Dalton Transactions
影响因子：
4
作者：
Tomat, Elisa;Curtis, Clayton J.;Astashkin, Andrei V.;Conradie, Jeanet;Ghosh, Abhik
通讯作者：
Ghosh, Abhik

Oxidative Route to Indoles via Intramolecular Amino-Hydroxylation of o -Allenyl Anilines

通过邻联烯基苯胺的分子内氨基羟基化氧化为吲哚的路线

DOI：
10.1021/acs.joc.1c01379
发表时间：
2021
期刊：
The Journal of Organic Chemistry
影响因子：
0
作者：
Lauta, Nicholas R.;Williams, Ryan E.;Smith, David T.;Kumirov, Vlad K.;Njardarson, Jon T.
通讯作者：
Njardarson, Jon T.

Anionic Amino-Cope Rearrangement Cascade Synthesis of 2,4-Substituted Benzoate Esters from Acyclic Building Blocks

由无环结构单元阴离子氨基-Cope重排级联合成 2,4-取代苯甲酸酯