MRI: Acquisition of 500 MHz Nuclear Magnetic Resonance Spectrometer for Research and Education Infrastructure Enhancement at Michigan Technological University and Upper Peninsula

MRI：采购 500 MHz 核磁共振波谱仪，用于增强密歇根理工大学和上半岛的研究和教育基础设施

• 批准号: 2117318
• 负责人: Marina Tanasova
• 金额: $ 44.61万
• 依托单位: Michigan Technological University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2117318&HistoricalAwards=false
• 关键词: MRI; Acquisition; 500; MHz; Nuclear

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Michigan Technological University is acquiring a 500 MHz nuclear magnetic resonance (NMR) spectrometer to support the research of Marina Tanasova and colleagues Haiying Liu, Shiyue Fang, Evan Kane and Daisuke Minakata. This spectrometer allows research in a variety of fields including biological chemistry, organic synthesis, nucleotides, polymers, and environmental science. NMR spectroscopy is a powerful tool that chemists use for the elucidation of molecular structure. Unknown substances can be identified, specific arrangement of atoms in molecules can be determined, and the dynamics of interactions between molecules in solution or in the solid state can be studied. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution as well as regionally.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially facilitates the exploration of substrate selection by facilitative sugar transporters gluts with diverse stable sugar mimics, the execution of solid-phase synthesis of monodisperse polyethylene glycol and its derivatives, and the development of technologies for the synthesis of sensitive oligodeoxynucleotides. The instrument is also used to support the design and development of conjugated polymers with xanthene units and three-emission conjugated polymers with xanthene units fused with dyes. In addition, it allows for the investigation of the photochemical fate of dissolved amino acids in natural aquatic environments, the understanding of soil carbon cycling via pore water-dissolved organic matter, and the study of electro-responsive underwater adhesive based on mussel adhesive.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由重大研究仪器项目和化学研究仪器项目共同支持。密歇根理工大学正在购买一台 500 MHz 核磁共振 (NMR) 波谱仪，以支持 Marina Tanasova 及其同事 Haiying Liu、Shiyue Fang、Evan Kane 和 Daisuke Minakata 的研究。该光谱仪可用于多种领域的研究，包括生物化学、有机合成、核苷酸、聚合物和环境科学。核磁共振波谱是化学家用来阐明分子结构的强大工具。可以识别未知物质，可以确定分子中原子的特定排列，并且可以研究溶液或固态中分子之间相互作用的动力学。对于进行前沿研究的化学家来说，使用最先进的核磁共振波谱仪至关重要。该仪器是该机构以及该地区化学和生物化学本科生和研究生教学以及研究和研究培训的重要组成部分。核磁共振波谱仪的获奖旨在加强各级的研究和教育。它特别有助于探索促进性糖转运蛋白与多种稳定糖模拟物之间的底物选择、单分散聚乙二醇及其衍生物的固相合成以及敏感寡脱氧核苷酸合成技术的开发。该仪器还用于支持呫吨单元共轭聚合物和呫吨单元与染料融合的三发射共轭聚合物的设计和开发。此外，它还可以研究天然水生环境中溶解氨基酸的光化学命运，通过孔隙水溶解的有机物了解土壤碳循环，以及基于贻贝粘合剂的电响应水下粘合剂的研究。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。