Center for Sustainable Nanotechnology

可持续纳米技术中心

• 批准号: 1503408
• 负责人: Robert Hamers
• 金额: $ 2000万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1503408&HistoricalAwards=false
• 关键词: Center; Sustainable; Nanotechnology

The Center for Sustainable Nanotechnology (CSN) enables fundamental studies of the specific molecular interactions expected to occur when the surfaces of engineered nanoparticles come into contact with biological interfaces and components. The chemical insight gained from molecular and mechanistic studies of nano-bio interactions is used to intentionally design nanomaterials that provide the desired technical functions while also minimizing potentially adverse consequences with the environment. CSN research leads to introduction of a new generation of safer nanomaterials that may impact multiple sectors of the economy including energy, transportation, electronics, food, and agriculture. The CSN prepares a new generation of scientific innovators by providing education and professional development opportunities focused on innovation, communication, leadership, and interdisciplinary scientific skills. CSN researchers actively encourage diversity within chemistry through CSN-run workshops on overcoming implicit bias, recruitment of graduate students and postdocs, and Center-sponsored research experiences for students and faculty from underrepresented groups as well as veteran undergraduates. CSN researchers encourage diversity in public engagement, develops and practices informal communication skills, and expands the highly successful sustainable-nano.com blog to include Spanish language content, K-12 activity materials, podcasts, and videos.CSN integrates experiments with computation in three integrated research focus areas (RFAs). RFA1 develops new materials with precisely controlled structure and properties, molecular-level characterization tools such as advanced non-linear optical methods and sub-diffraction imaging, and novel computational methods spanning length scales from nanometers to millimeters. RFA2 uses the RFA1 tool kit to understand, control, and predict how nanomaterials attach to, penetrate, and alter cell surfaces using lipid bilayers as model systems for cell membranes. RFA3 determines the molecular processes by which pristine and environmentally transformed nanomaterials interact with living systems with diverse cellular chemistries, ranging from single cell to multi-cellular organisms. The integration of these three RFAs enables the Center to establish how nanomaterial properties and behavior impact biological outcomes. This knowledge leads to reliable predictions of biological responses to existing and future nanomaterials and guides the design and synthesis of safe, sustainable nanomaterials. In pursuing the project goals, the CSN puts particular emphasis on the synthesis, characterization, and molecular-level interactions initiated by complex, composite nanomaterials that are being used in emerging and future nano-enabled commercial technologies.The Center for Sustainable Nanotechnology is funded as part of the Centers for Chemical Innovation (CCI) program.

可持续纳米技术中心 (CSN) 能够对工程纳米颗粒表面与生物界面和组件接触时预期发生的特定分子相互作用进行基础研究。从纳米生物相互作用的分子和机制研究中获得的化学见解可用于有意设计纳米材料，以提供所需的技术功能，同时最大限度地减少对环境的潜在不利影响。 CSN 研究导致引入新一代更安全的纳米材料，可能会影响能源、交通、电子、食品和农业等多个经济部门。 CSN 通过提供专注于创新、沟通、领导力和跨学科科学技能的教育和专业发展机会，培养新一代科学创新者。 CSN 研究人员通过 CSN 举办的克服隐性偏见的研讨会、招募研究生和博士后以及中心资助的为来自代表性不足群体的学生和教师以及资深本科生提供研究经验，积极鼓励化学领域的多样性。 CSN 研究人员鼓励公众参与的多样性，发展和实践非正式沟通技巧，并将非常成功的 Sustainable-nano.com 博客扩展为包括西班牙语内容、K-12 活动材料、播客和视频。CSN 将实验与计算集成在三个方面综合研究重点领域（RFA）。 RFA1 开发具有精确控制结构和性能的新材料、分子级表征工具（例如先进的非线性光学方法和亚衍射成像）以及跨越纳米到毫米长度尺度的新颖计算方法。 RFA2 使用 RFA1 工具包来理解、控制和预测纳米材料如何附着、渗透和改变细胞表面，使用脂质双层作为细胞膜的模型系统。 RFA3 确定原始和环境转化的纳米材料与具有不同细胞化学性质的生命系统（从单细胞到多细胞生物体）相互作用的分子过程。这三个 RFA 的整合使该中心能够确定纳米材料的特性和行为如何影响生物结果。这些知识可以对现有和未来纳米材料的生物反应进行可靠预测，并指导安全、可持续纳米材料的设计和合成。在实现项目目标的过程中，CSN 特别强调由复杂复合纳米材料引发的合成、表征和分子级相互作用，这些材料正在新兴和未来的纳米商业技术中使用。可持续纳米技术中心的资金来源为：化学创新中心 (CCI) 计划的一部分。

项目成果

Adsorption Dynamics and Structure of Polycations on Citrate-Coated Gold Nanoparticles

聚阳离子在柠檬酸盐包覆的金纳米粒子上的吸附动力学和结构

• DOI: 10.1021/acs.jpcc.8b05202
• 发表时间: 2018-08-01
• 期刊: The Journal of Physical Chemistry C
• 作者: Gene Chong;R. Hern;ez;ez
• 通讯作者: ez

β-Cyclodextrin Polymers on Microcrystalline Cellulose as a Granular Media for Organic Micropollutant Removal from Water

微晶纤维素上的β-环糊精聚合物作为去除水中有机微污染物的颗粒介质

• DOI: 10.1021/acsami.8b22100
• 发表时间: 2019-01
• 期刊: ACS Applied Materials & Interfaces
• 影响因子: 9.5
• 作者: Alzate;Ling, Yuhan;Li, Chenjun;Frank, Benjamin P.;Bleher, Reiner;Fairbrother, D. Howard;Helbling, Damian E.;Dichtel, William R.
• 通讯作者: Dichtel, William R.

Preparation of Colloidally Stable Positively Charged Hollow Silica Nanoparticles: Effect of Minimizing Hydrolysis on ζ Potentials

胶体稳定带正电的空心二氧化硅纳米粒子的制备：最小化水解对 δ 电势的影响

• DOI: 10.1021/acs.langmuir.9b01042
• 发表时间: 2019-05
• 期刊: Langmuir
• 影响因子: 3.9
• 作者: Kang, Hyunho;Long, Davis J.;Haynes, Christy L.
• 通讯作者: Haynes, Christy L.

Energy Storage Materials as Emerging Nano-Contaminants

储能材料作为新兴纳米污染物

• DOI: 10.1021/acs.chemrestox.0c00080
• 发表时间: 2020-01
• 期刊: Chemical Research in Toxicology
• 影响因子: 4.1
• 作者: Hamers; Robert J
• 通讯作者: Robert J

Coating iron oxide nanoparticles with mesoporous silica reduces their interaction and impact on S. oneidensis MR-1

用介孔二氧化硅涂覆氧化铁纳米颗粒可减少它们对 S. oneidensis MR-1 的相互作用和影响

• DOI: 10.1016/j.chemosphere.2019.124511
• 发表时间: 2019-12
• 期刊: Chemosphere
• 影响因子: 8.8
• 作者: Buchman, Joseph T.;Pho, Thomas;Rodriguez, Rebeca S.;Feng, Z. Vivian;Haynes, Christy L.
• 通讯作者: Haynes, Christy L.