Electrophysiology amplifiers and software for Sleep Lab

用于睡眠实验室的电生理学放大器和软件

• 批准号: RTI-2020-00426
• 负责人: Cote, Kimberly
• 金额: $ 10.19万
• 依托单位: Brock University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=693529
• 关键词: Electrophysiology; amplifiers; software; Sleep; Lab

The Sleep Research Laboratory at Brock University is a 3-bedroom facility where we investigate sleep, performance and cognition in humans. The long-term goal of the program of research is to understand the functional role of sleep in waking performance. Dr. Cote built the lab in 2000 with state-of-the-art equipment to record brain activity from multiple scalp sites during sleep and waking states. Recording brain wave activity from 64 sites across the scalp provides a dynamic picture or map of changes in arousal and attention that vary across the day and night. Dr. Cote and her students have published extensively on diverse topics including the effects of sleep loss on brain function and performance, the role of sleep in memory consolidation, cognitive benefits of a nap, consciousness at sleep onset and throughout the night, and quantitative analysis of EEG during sleep and wakefulness as it relates to human performance. ******The equipment used to record sleep and brain activity during waking performance is no longer functional. Replacement of the recording amplifiers is crucial for continuation of the program of research and training of highly qualified personnel. Software updates will also improve the efficiency of research output by providing access to modern analysis routines. This equipment will be used for Dr. Cote's NSERC-funded research which investigates the role of sleep in waking information processing. The most recent research grant (funded 2019-2024) aims to investigate the role of REM and non-REM sleep in emotion processing in particular. We will use highly novel paradigms such as deep sleep enhancement with auditory stimulation. Students at all levels receive highly specialized training in electrophysiology in the context of both sleep and waking cognitive performance. As many Canadians do not get the sleep they need, this research may help people to improve performance (work, scholastic, sport) through optimizing sleep, and may also inform intervention strategies in individuals with sleep, emotion, or behavioural disorders. *****

布罗克大学的睡眠研究实验室是一家三卧室设施，我们研究了人类的睡眠，表现和认知。研究计划的长期目标是了解睡眠在清醒性能中的功能作用。 Cote博士于2000年使用最先进的设备建立了该实验室，可在睡眠和醒来状态下从多个头皮站点记录大脑活动。从头皮上的64个地点记录脑波活动，提供了整个白天和黑夜各种唤醒和注意力变化的动态图片或图。 Cote博士和她的学生广泛发表了各种主题，包括睡眠丧失对大脑功能和表现的影响，睡眠在记忆巩固中的作用，NAP的认知益处，睡眠开始和整夜的意识以及与人类表现有关的睡眠和觉醒的定量分析。 ******用于记录睡眠和大脑活动期间睡眠和大脑活动的设备不再起作用。替换录制放大器对于延续高素质人员的研究和培训计划至关重要。软件更新还将通过提供对现代分析例程的访问来提高研究输出的效率。该设备将用于Cote博士的NSERC资助研究，该研究调查了睡眠在唤醒信息处理中的作用。最新的研究赠款（资助2019 - 2024年）旨在调查REM和非REM睡眠在情绪处理中的作用。我们将使用高度新颖的范式，例如通过听觉刺激增强睡眠。在睡眠和唤醒认知表现的背景下，各个级别的学生都接受了高度专业的电生理培训。由于许多加拿大人没有获得所需的睡眠，因此这项研究可能会通过优化睡眠来帮助人们提高表现（工作，学业，运动），并可能为患有睡眠，情感或行为障碍的人的干预策略提供依据。 *****