PGX technology for drying of biopolymers and their impregnation with bioactives

用于生物聚合物干燥及其生物活性物质浸渍的 PGX 技术

• 批准号: 500236-2016
• 负责人: Temelli, Feral
• 金额: $ 7.83万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=607988
• 关键词: PGX; technology; drying; biopolymers; their

PGX (Pressurized Gas eXpanded liquid) technology has been developed and patented by the applicants at the University of Alberta. It is licensed to Ceapro Inc for them to scale it up from the laboratory to commercial scale. With this technology it is possible to dry high molecular weight biopolymers, like polysaccharides or proteins, and generate powders with different characteristics. It is challenging to perform such drying using traditional technologies because high molecular weight biopolymers form highly viscous or very thick solutions. By controlling the processing parameters associated with the PGX technology, powders in different forms, ranging from very fine to coarse can be obtained. Because the powders obtained have a large surface area, they can be used as a carrier for other "natural" components with health benefits. Such bioactive components can be deposited onto the powders in a second step of the PGX process. Because the bioactive components are in general sensitive to heat and can be damaged easily, the low processing temperature of 40oC is particularly suitable for their handling. It is anticipated that such carrier systems for bioactive ingredients would make them more effective in the human body. The proposed research aims to study the formation of such ingredients based on different bioactive/biopolymer combinations and to carry out detailed characterization to better understand their interactions and performance of the technology for a variety of ingredients. The findings will be invaluable to expand the utilization of the technology and to generate novel high-value ingredients, targeting applications in functional food, dietary supplement and cosmetic products with far reaching benefits. Training of highly qualified personnel by the research team members working in close collaboration will contribute to meeting the demand for such individuals. The proposed research is essential to achieve the full potential of this promising technology at commercial scale and contribute to growing the bioeconomy.

PGX（加压气体膨胀的液体）技术已由艾伯塔大学的申请人开发和专利。它已获得Ceapro Inc的许可，使他们将其从实验室扩展到商业规模。使用该技术，可以干燥高分子重量生物聚合物，例如多糖或蛋白质，并产生具有不同特征的粉末。使用传统技术进行这种干燥是一项挑战，因为高分子量生物聚合物形成高粘性或非常厚的溶液。通过控制与PGX技术相关的处理参数，可以以不同形式的粉末获得从非常细到粗糙的粉末。由于获得的粉末具有较大的表面积，因此可以用作具有健康益处的其他“天然”组件的载体。这种生物活性成分可以在PGX过程的第二步中沉积到粉末上。由于生物活性成分通常对热量敏感并且很容易损坏，因此低处理温度为40OC特别适合其处理。可以预料，这种用于生物活性成分的载体系统会使它们在人体中更有效。拟议的研究旨在根据不同的生物活性/生物聚合物组合研究此类成分的形成，并进行详细的表征，以更好地了解它们对各种成分的技术的相互作用和性能。这些发现将是无价的，可以扩大技术的利用并产生新颖的高价值成分，针对功能性食品，饮食补充剂和化妆品的应用，并具有较远的收益。研究小组成员密切合作对高素质的人员进行培训将有助于满足对此类人的需求。拟议的研究对于在商业范围内实现这项有前途的技术的全部潜力至关重要，并有助于发展生物经济。