Activity Space Adversity and Racial Disparities in Adolescent Health

青少年健康中的活动空间逆境和种族差异

• 批准号: 10754093
• 负责人: Christopher R Browning
• 金额: $ 68.62万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10754093
• 关键词: Adolescence; Adolescent; Adolescent Development; Adult; Age; Area; Black race; C-reactive protein; COVID-19 pandemic; Caregivers; Chronic Disease; Communities; Data; Data Analyses; Data Collection; Data Sources; Development; Dimensions; Disparity; Ecological momentary assessment; Exhibits; Exposure to; Hair; Health; Heterogeneity; Home; Hydrocortisone; Individual; Inflammation; Inflammatory; Intervention; Investigation; Link; Location; Measures; Mediating; Mental Health; Neighborhoods; Outcome; Patient Self-Report; Perception; Personal Satisfaction; Phase; Physiological; Police; Process; Race; Reaction; Research; Resolution; Risk; Role; Safety; Sampling; Shapes; Stress; Structural Racism; Surveys; Time; Victimization; Violence; Work; Youth; adolescent health; behavioral health; children of color; cohort; design; experience; heart rate variability; innovation; killings; metropolitan; microaggression; neglect; novel; psychologic; racial difference; racial disparity; racial diversity; racial identity; response; segregation; stress reactivity; substance use; violence exposure

PROJECT SUMMARY Prior research has documented substantial differences in levels of physiological stress among Black- and White- identifying individuals during adolescence, a period of particular importance from a developmental perspective, which may shape disparities in chronic disease in adulthood. The proposed project seeks to explore the role of exposure to multiple dimensions of activity-space adversity (ASA) – including area-level violence, elevated policing, and racial exclusivity – in contributing to everyday (real-time) perceptions of both physical and psychological unsafety and their contribution to explaining racial physiological stress disparities during adolescence (Aim 1). We will also consider the impact of ASA exposures, unsafety perceptions, and physiological stress as predictors of substance use and mental health outcomes (Aim 2). We will explore the moderating influence of other-perceived race – or the degree to which an individual believes others perceive their race to be Black in public interactions – on ASA exposure and unsafety effects on physiological stress and health outcomes. The project will collect aim-relevant data on a racially diverse cohort of adolescents residing in the Columbus, OH metropolitan area employing an innovative two-stage design: The first phase will produce rich cross-sectional data (N=700) including standard survey items for youth and their caregivers; estimates of youth ASA exposures from self-reported routine activity locations combined with extensive contextual ratings and administrative data, physiological stress markers (cortisol and inflammatory), and health outcomes. The second phase will involve a supplemental intensive longitudinal data collection period taking place over a six-month period for a subsample of Phase 1 youth (N=300) selected using a novel exposure-based sampling strategy. Data collected during this supplemental phase will include an unprecedented combination of continuous high- resolution GPS tracking; ecological momentary assessments of perceived psychological and physical safety; continuously-sensed heart rate variability; and hair cortisol concentration and C-reactive protein measured at three additional time points. In addition to analyses of the novel data sources produced by the project, by drawing on data from the Adolescent Health and Development in Context Study (2014-2016) previously conducted by our study team, we will also examine recent historical changes in ASA exposures, racial disparities in safety and physiological stress, and their health consequences.

项目概要 先前的研究已经记录了黑人和白人之间生理压力水平的巨大差异 从发展的角度来看，青春期是一个特别重要的时期， 这可能会影响成年期慢性疾病的差异。拟议的项目旨在探讨慢性疾病的作用。 暴露于活动空间逆境（ASA）的多个维度——包括地区级暴力、升高 治安和种族排他性——有助于对身体和身体的日常（实时）感知 心理不安全感及其对解释种族生理压力差异的贡献 我们还将考虑 ASA 暴露、不安全认知和行为的影响。 生理压力作为物质使用和心理健康结果的预测因素（目标 2）。 调节他人感知种族的影响——或者个人相信他人感知的程度 他们在公共互动中争当黑人——关于 ASA 暴露和对生理压力和不安全影响 该项目将收集居住在不同种族青少年群体中的目标相关数据。 俄亥俄州哥伦布大都市区采用创新的两阶段设计：第一阶段将生产丰富的 横截面数据（N=700），包括针对青少年及其照顾者的标准调查项目； 自我报告的日常活动地点的 ASA 暴露量与广泛的背景评级相结合 管理数据、生理压力标志物（皮质醇和炎症）和健康结果。 该阶段将涉及为期六个月的补充密集纵向数据收集期 使用新颖的基于暴露的抽样策略选择第一阶段青少年子样本（N = 300）的时期。 在此补充阶段收集的数据将包括前所未有的连续高 分辨率 GPS 跟踪；感知心理和身体安全的生态瞬时评估； 连续检测心率变异性；以及测量头发皮质醇浓度和 C 反应蛋白 除了对项目产生的新数据源进行分析外，还通过绘图分析了三个额外的时间点。 基于之前由以下机构进行的青少年健康与发展背景研究（2014-2016）的数据 我们的研究团队还将研究 ASA 暴露的近期历史变化、安全性和种族差异 生理压力及其健康后果。