Shared Resources - Tissue Procurement

共享资源 - 组织采购

• 批准号: 8340168
• 负责人: George J. Weiner
• 金额: $ 9.13万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-19 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340168
• 关键词: Basic Science; Benign; Blood; Cancer Center Support Grant; Clinic; Clinical Data; Collection; Computer software; Consent; DNA; Databases; Freezing; Future; Goals; Human; Human Resources; Individual; Informatics; Institution; Instruction; Laboratories; Lead; Leadership; Link; Malignant - descriptor; Malignant Neoplasms; Medical; Medical center; Normal tissue morphology; Operative Surgical Procedures; Patient Care; Patients; Procedures; Quality Control; Regulation; Research; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Sampling; Science; Secure; Services; Source; Specimen; Surgical Pathology; Suspension substance; Suspensions; Time; Tissue Procurements; Tissues; Translating; Translational Research; Universities; Work; anticancer research; base; design; human tissue; meetings; neoplasm resource; operation

PROJECT SUMMARY (See instructions): Tissue Procurement Core Ready access to both benign and malignant tissue is a valuable resource for cancer investigators. The Tissue Procurement Core is designed to collect and store high quality tissue specimens from a variety of sources and make these available to HCCC investigators based on the science proposed. The Core insures that these activities are performed in compliance with all rules and regulations covering such activity. The Core and its personnel work in cooperation with clinicians from various departments to: 1) Identify and consent patients from whom collection may be appropriate. 2) Work closely with appropriate individuals in the Surgical Pathology Laboratory to insure adequate patient care while maximizing the number of collected specimens 3) Enter information about specimens into a secure data base and store appropriately 4) Implement rigorous quality control procedures 5) Distribute available tissue to investigators for high quality cancer research The HCCC and University of lowa CTSA are collaborating to further strengthen access to biospecimens. The Tissue Procurement Core has implemented CaTISSUE to enhance the informatics infrastructure for Tissue Procurement, and is working to develop an approach to obtaining consent at the time of registration to the medical center, and link tissues with deidentified clinical data, that will further enhance the utility of tissue for HCCC investigators.

项目摘要（请参阅说明）： 组织采购核心 准备进入良性组织和恶性组织是癌症的宝贵资源 调查人员。组织采购核心旨在收集和存储高质量 来自各种来源的组织标本，并根据提出的科学使HCCC研究人员提供这些标本。核心确保这些活动是按照涵盖此类活动的所有规则和法规进行的。核心及其人员与来自各个部门的临床医生合作的工作： 1）确定和同意患者可能合适的患者。 2）与外科病理实验室中适当的人紧密合作，以确保足够的患者护理，同时最大化收集的标本数量 3）将有关标本的信息输入安全数据库并适当存储 4）实施严格的质量控制程序 5）向研究人员分发可用的组织进行高质量癌症研究 HCCC和Lowa CTSA大学正在合作，以进一步加强进入 生物测量。组织采购核心已实施了CATISSUE，以增强组织采购的信息基础设施，并正在努力开发一种在注册到医疗中心时获得同意的方法，并将组织与已识别的临床数据联系起来，这将进一步增强HCCC研究者的组织效用。