Shared Resources - Central Microscopy Research Facility

共享资源 - 中央显微镜研究设施

• 批准号: 8340157
• 负责人: George J. Weiner
• 金额: $ 8.76万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-19 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340157
• 关键词: Advisory Committees; Animals; Bioluminescence; Businesses; Cancer Center Support Grant; Chemicals; Clinical; Confocal Microscopy; Consultations; Cryoultramicrotomy; Development; Diamond; Educational process of instructing; Educational workshop; Electron Microscope; Electron Microscopy; Equipment; Faculty; Film; Fluorescence Microscopy; Freeze Fracturing; Freeze Substitution; Freezing; Funding; Glass; Goals; Image; In Situ Hybridization; Individual; Instruction; Laboratories; Lasers; Light; Light Microscope; Methods; Microscope; Microscopy; Microtome - medical device; Optics; Paraffin; Peer Review; Research; Research Personnel; Resource Sharing; Resources; Roentgen Rays; Sampling; Scanning; Scanning Probe Microscopes; Services; Slide; Specimen; Spectrum Analysis; Staining method; Stains; Students; System; Techniques; Technology; Training; Vacuum; anticancer research; base; cryostat; digital; digital imaging; experience; falls; fluorescence imaging; in vivo; instrument; instrumentation; interest; laser capture microdissection; light microscopy; member; operation; pressure; programs; research facility; sample fixation; square foot; tissue preparation; tomography; tool; transmission process

Central Microscopy Microscopy remains central to both laboratory and clinical cancer research. The principal goal of the Central Microscopy Research Facility (CMRF) is to provide services and instruction to HCCC investigators interested in using microscopy technology for cancer research. The CMRF provides technical assistance for labor intensive techniques and ready access to highly specialized and expensive equipment. It supports cancer research being done by members of all 6 research programs. Specific services available to HCCC investigators include expertise related to tissue preparation, fixation and staining for: 1) Light microscopy 2) Histochemical and fluorescence microscopy 3) Confocal, multiphoton and electron microscopy 4) In situ hybridization 5) Elemental and chemical characterization 5) In vivo small animal imaging using the IVIS imaging system The CMRF provides consultation and assistance to HCCC investigators in the development and application of new and specialized morphological methods relevant to cancer research. In 2009, 80 HCCC members with peer reviewed funding utilized the CMRF.

中央显微镜 显微镜仍然是实验室和临床癌症研究的核心。中央显微镜研究机构（CMRF）的主要目标是向有兴趣使用显微镜技术进行癌症研究的HCCC研究人员提供服务和指导。 CMRF为劳动提供技术帮助 密集的技术并准备使用高度专业且昂贵的设备。它支持所有6个研究计划的成员进行的癌症研究。 HCCC调查人员可用的特定服务包括与组织准备，固定和染色有关的专业知识： 1）光学显微镜 2）组织化学和荧光显微镜 3）共聚焦，多光子和电子显微镜 4）原位杂交 5）元素和化学表征 5）使用IVIS成像系统的体内小动物成像 CMRF在与癌症研究相关的新的和专业的形态学方法的开发和应用方面为HCCC研究人员提供咨询和帮助。 2009年，有80名HCCC成员进行了同行审查的资金，利用了CMRF。