Population Core

核心人口

• 批准号: 10252837
• 负责人: Jennifer Beth Unger
• 金额: $ 90.16万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-19 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10252837
• 关键词: Address; Adolescence; Adolescent; Age; Archives; Award; Behavior; California; Characteristics; Child Health; Cohort Analysis; Collaborations; Complement; Confidential Information; Data; Data Analyses; Data Collection; Database Management Systems; Databases; Development; Electronic cigarette; Enrollment; Ensure; Epidemiology; Exposure to; Funding; Goals; Happiness; Health; Health Surveys; Human; Infrastructure; Laboratory Study; Learning; Length; Marketing; Measurement; Meta-Analysis; Methods; Participant; Pattern; Pennsylvania; Population; Population Assessment of Tobacco and Health; Population Database; Population Heterogeneity; Positioning Attribute; Preventive Medicine; Recreation; Regulation; Research; Research Personnel; Resources; Sampling; San Francisco; Schools; Science; Scientist; Smoker; Smoking; Subgroup; Sum; Surveys; Target Populations; Testing; Texas; Tobacco; Tobacco use; Universities; Update; Virginia; Vulnerable Populations; Work; Youth; aged; behavior observation; career; cohort; community based participatory research; data integration; design; early adolescence; electronic cigarette use; experience; follow-up; member; ninth grade; non-smoking; recruit; response; smoking cessation; social media; tobacco products; tobacco regulatory science; trend; young adult

Abstract: Population Core The projects in the USC-TCORS will require access to population resources with sufficient representation of tobacco product exposures, population subgroups, and longitudinal follow-up. The USC-TCORS Population Core (PC) will provide the Center with a sufficiently large, diverse, and well-followed sample to address the proposed scientific goals. We leverage data from a highly successful 2013-2018 initial funding period, in which we developed and tracked two cohorts with excellent retention. For 2018-2023, PC proposes the following aims. Aim 1. Expand, follow, track, and assess a Center-wide combined cohort. The PC will leverage data collected during the current award from two samples of adolescents, now young adults, for additional follow-up: (i) the Children's Health Study (CHS), which has extensive smoking information collected through schools since early adolescence, and complete information on tobacco product use starting at age 16-18 years; CHS participants will be aged 20-22 in 2018 (N=1,366); and (ii) the Happiness and Health (H&H) study, which has comprehensive tobacco product use information and covariates since enrollment in 2013 at age 14; H&H par- ticipants will be aged 18-19 in 2018 (N=2,534). Using now well-established methods, we will also recruit a new younger sample, the Trends in Tobacco Use Survey (TITUS) study, from 9th grade classrooms (age 14) in schools where CHS and H&H were originally drawn from (N=2,500). We will integrate these three resources into combined Center-wide cohort of 6,400 youth and young adults. The PC will conduct annual surveys on the Center-wide cohort to serve P1 and P3 aims, utilizing a common electronic survey infrastructure developed in partnership with the Administrative Core and ensuring common survey items across projects. The PC will also collect and manage a database of cohort data to be made available for the other projects, Rapid Re- sponse Projects, collaborations with other TCORSs, and junior investigator pilots (from the Career Enhance- ment Core). The database will be used for secondary data analysis projects and to identify populations with selected characteristics for recruitment into P4. The database will also be drawn upon for shared aims regard- ing social media exposure and tobacco use for P1 and P3. Finally, the database will be a resource for addi- tional original data collection projects. Aim 2. Facilitate access to other population resources outside of the Center-wide cohort within the USC Department of Preventive Medicine. The PC will enhance existing connec- tions with and access to population cohorts and archival databases including numerous diverse samples. In sum, PC cohorts will provide an unmatched population resource in terms of diversity, follow-up length, meas- urement intensity, and richness of data. Our resource will complement and provide unique information to other large samples such as the Population Assessment of Tobacco and Health survey by providing population di- versity, product diversity assessment, and tobacco product exposure analysis that is not otherwise available.

摘要：核心人口 USC-TCORS 中的项目将需要获得具有足够代表性的人口资源 烟草产品暴露、人群亚组和纵向随访。 USC-TCORS 人口 核心（PC）将为中心提供足够大、多样化且易于追踪的样本来解决 提出的科学目标。我们利用 2013-2018 年初始融资期间非常成功的数据，其中 我们开发并跟踪了两个具有出色保留率的队列。对于2018-2023年，PC提出以下建议 目标。目标 1. 扩展、跟踪、跟踪和评估中心范围内的联合队列。 PC将利用数据 在当前颁奖期间从青少年（现在是年轻人）的两个样本中收集的样本，以进行额外的后续行动： (i) 儿童健康研究 (CHS)，该研究通过学校收集了大量吸烟信息 从青春期早期开始，以及从 16 岁至 18 岁开始使用烟草制品的完整信息； CHS 2018年参与者年龄为20-22岁（N=1,366）； (ii) 幸福与健康 (H&H) 研究 自 2013 年 14 岁入学以来的全面烟草产品使用信息和协变量； H&H 帕- 2018 年参与者年龄为 18-19 岁（N=2,534）。使用现在行之有效的方法，我们还将招募新的 烟草使用趋势调查 (TITUS) 研究中的年轻样本来自 9 年级教室（14 岁） CHS 和 H&H 最初抽取的学校 (N=2,500)。我们将整合这三种资源 纳入整个中心范围内的 6,400 名青少年和年轻人的队列。 PC将进行年度调查 利用开发的通用电子调查基础设施，服务于 P1 和 P3 目标的中心范围群体 与行政核心合作，确保跨项目的共同调查项目。电脑将 还收集和管理队列数据的数据库，以供其他项目使用，Rapid Re- 赞助项目、与其他 TCORS 的合作以及初级调查员飞行员（来自职业增强- 换核心）。该数据库将用于二次数据分析项目并确定具有以下特征的人群： 选择招募 P4 的特征。该数据库还将用于实现共同目标： P1 和 P3 的社交媒体曝光和烟草使用情况。最后，数据库将成为附加资源 国家原始数据收集项目。目标 2. 促进获取境外其他人口资源 南加州大学预防医学系的中心队列。 PC将增强现有的连接 与人口队列和档案数据库（包括大量不同样本）的联系和访问。在 总而言之，PC队列将在多样性、随访长度、测量方面提供无与伦比的人口资源。 数据的丰富程度和强度。我们的资源将补充并向其他人提供独特的信息 大样本，例如烟草人口评估和健康调查，通过提供人口 多样性、产品多样性评估和烟草产品暴露分析，这些都是其他方式无法获得的。