Predictors of Speech Ability in Children with Down Syndrome

唐氏综合症儿童言语能力的预测因素

基本信息

批准号：
10584659
负责人：
Stephen Mark Camarata
金额：
$ 15.15万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-01 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10584659
关键词：
Academy Accent Accounting Acoustics Adolescence Age Articulation Articulators Biological Assay Birth Child Clinical Clinical Trials Cognitive Communication Comprehension Data Development Down Syndrome Frequencies Future Goals Growth Human Individual Intervention Intervention Studies Investigational Therapies Language Language Disorders Learning Linguistics Literature Longitudinal Studies Measures Medicine Modeling Motor Motor Skills Outcome Paper Participant Periodicity Persons Process Production Reading Reporting Research Research Project Grants School-Age Population Series Speech Speech Development Speech Disorders Speech Intelligibility Structure Students Testing Translational Research Variant Vocabulary Work base cognitive ability design experience improved insight lexical oral motor phonology post intervention prospective reading ability skills speech accuracy therapy design

项目摘要

ABSTRACT Speech is a critical aspect of the human experience and usually develops in a “seemingly automatic process that continues from birth through adolescence (p.1, NAM, 2016)” and underlies many related abilities (e.g., language and reading, see National Academy of Medicine Report on Speech and Language Disorders, 2016). Many individuals with Down Syndrome (Trisomy 21, DS) struggle to communicate and participate more fully in human communication and educational learning experiences because their speech is difficult to understand. The purpose of the proposed project is to measure speech-articulation accuracy and speech intelligibility, and their proposed primary predictors at study entry in 20 children with DS age 7;0 to 12;11. A validated treatment, speech recast intervention (see Yoder, Camarata & Woynaroski, 2016) will be used to drive growth in speech intelligibility as a means of evaluating changes in potential sequelae of change. This integrated study will include measures of speech- articulation accuracy, speech-prosody, general cognitive ability, receptive vocabulary skills, and clinical assay of oral-motor ability as potential predictors of speech intelligibility growth in DS. We will also be measuring suprasegmental and rhythmic factors associated with growth. The results of this study will provide important information on factors that contribute to intelligible speech in DS and subsequently provide the basis for refining and future intervention investigations of treatment for speech deficits in children with DS.

抽象的言语是人类经验的一个重要方面，通常以“看似从出生一直持续到青春期的自动过程（第 1 页，NAM，2016）”和是许多相关能力的基础（例如语言和阅读，请参阅美国国家医学院关于言语和语言障碍的报告，2016 年）。（21 三体，DS）难以沟通并更充分地参与人类沟通和教育学习经历，因为他们的言语难以理解。拟议项目的目的是测量语音清晰度和语音 20 名 7 岁 DS 儿童的智力及其在进入研究时提出的主要预测因素；0 至 12;11。经过验证的治疗、言语重铸干预（参见 Yoder、Camarata 和 Woynaroski，2016）将被用来推动语音智能的增长，作为一种评估手段这项综合研究将包括言语的测量。发音准确性、言语韵律、一般认知能力、接受词汇能力，以及口腔运动能力的临床分析作为 DS 语音清晰度增长的潜在预测因子。我们还将测量与生长相关的超节段和节律因素。这项研究的结果将提供有关影响可理解性的因素的重要信息。 DS 中的演讲，并为随后的完善和未来干预提供基础 DS 儿童言语缺陷治疗的研究。