Short-term cognitive change in adults from 18 to 80

18 岁至 80 岁成年人的短期认知变化

• 批准号: 9025232
• 负责人: TIMOTHY SALTHOUSE
• 金额: $ 64.23万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-15 至 2020-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9025232
• 关键词: Accounting; Address; Adult; Age; Age-Years; Characteristics; Cognitive; Cognitive aging; Data Set; Dementia; Frequencies; Funding; Goals; Grant; Health; Impairment; Individual; Investigation; Lead; Life; Life Style; Link; Longitudinal Studies; Measurement; Measures; Nature; Participant; Pathology; Performance; Population; Property; Public Health; Quality of life; Research; Respondent; Role; Staging; Structure; Telephone; Testing; Time; Virginia; age effect; age related; age related cognitive change; clinical Diagnosis; cognitive ability; cognitive change; cognitive function; cognitive testing; emerging adult; experience; innovation; middle age; normal aging; organizational structure; pathological aging; public health relevance

 DESCRIPTION (provided by applicant): This is an application to continue research originally started in 2001, and expanded into a longitudinal study, known as the Virginia Cognitive Aging Project (VCAP), in 2005. Over 2,300 adults 18 - 95 years old have now completed at least two longitudinal occasions, with an average of 2.7 occasions and an average time in study of 5.1 years. The research proposed in the next funding period will extend the investigation of short-term longitudinal change in a broad variety of cognitive measures, with particular emphasis on adults under the age of 80. Although previous studies have found little or no cognitive change in longitudinal comparisons involving young and middle-aged adults, this research employs three methodological innovations, variable retest intervals, measurement bursts at each occasion, and continuous recruitment of new participants, that help distinguish age effects from experience (retest) effects, and that increase sensitivity to detect change by taking into account normal short-term variability in performance. Among the primary questions to be investigated are when does normal age-related cognitive change begin, the degree to which changes in different cognitive variables are independent of one another at different periods in adulthood, the role of prior test experience on the direction and magnitude of cognitive change at different ages, the degree to which factors such as one's cognitive or physical lifestyle moderate the amount of age-related change in different cognitive abilities at various periods in adulthood, and how early can normal and pathological trajectories of cognitive aging be distinguished. Specific aims during the next grant period are to: (1) Expand the characterization of normal cognitive aging across the range from about 18 to 80 years old; (2) Extend the investigation of the role of experience effects on cognitive change; (3) Investigate the structure and nature of cognitive change across different levels of analysis and across a wide range of ages; and (4) Increase sensitivity of VCAP tests to detect early stages of cognitive pathology among VCAP participants.

 描述（由应用程序提供）：这是一项最初始于2001年开始研究的应用程序，并扩展到了一项纵向研究，被称为弗吉尼亚认知衰老项目（VCAP），2005年。现已在2,300名成年人中至少完成了至少两次纵向的现场，平均是2.7次，并在2.7次中进行了2.7次和平均时间。在下一个资金期间提出的研究将扩大各种认知测量的短期纵向变化的投资，尤其强调了80岁以下的成年人。尽管在纵向比较中很少或没有认知比较几乎没有或没有认知的变化，而年轻人和中年成年人的纵向涉及的年轻人，这项研究员工的三个方法的启动，均可奔跑，奔跑，奔放，并造成了不断的启动。区分年龄效应与经验（重新测试）效应，并通过考虑正常的短期绩效可变性来增加对变化的敏感性。在要调查的主要问题中，与年龄相关的认知变化何时开始，不同认知变量的变化在成年时期的不同时期内相互独立，先前的测试经验在不同年龄段的认知变化方向和大小的作用，与某人的身体生活量的不同年龄段的不同年龄的程度，以及在各种情况下，各种能力的变化，以及在各种情况下的范围，以及在各种情况下的变化，以及在年龄上的变化，以及在年龄的不同年龄段，并且在年龄上的变化量是不同年龄的变化。早期可以区分认知衰老的正常和病理轨迹。在下一个赠款期间的具体目标是：（1）扩大正常认知衰老的表征，范围从约18岁到80岁； （2）扩展经验影响对认知变化的作用的投资； （3）研究不同级别的分析以及各个年龄段的认知变化的结构和性质； （4）提高VCAP测试的灵敏度，以检测VCAP参与者认知病理的早期阶段。