2011 Conference On Microbial Pathogenesis and Host Response

2011 年微生物发病机制和宿主反应会议

基本信息

批准号：
8204142
负责人：
DAVID J. STEWART
金额：
$ 1.5万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-08-15 至 2012-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8204142
关键词：
American Antibiotics Asians Bioterrorism Cells Cellular biology Chronic Disease Communicable Diseases Communities Development Diagnostic Discipline Disease Ensure Environment Eukaryotic Cell European Evolution Faculty Food Genome Genomics Goals HIV Health Healthcare Heart Diseases Hereditary Disease Immune response Immune system Immunology Incidence Infection Infection Control Infectious Agent Influentials International Intervention Laboratories Learning Length of Stay Malignant Neoplasms Medical Device Metabolism Microbe Microbial Antibiotic Resistance Microbial Biofilms Microbiology Molecular Molecular Genetics Natural Immunity New-Fill Oral Participant Pathogenesis Postdoctoral Fellow Process Public Health Published Comment Recording of previous events Research Research Personnel Resistance Role Schedule Science Scientist Selection Criteria Surface Time Ulcer Vaccines Virulence War Work abstracting antimicrobial base graduate student human disease human mortality improved insight interdisciplinary approach lectures meetings microbial microbial disease microbial host novel novel strategies pathogen patient population posters professor programs symposium tool transmission process unpublished works vaccine development

项目摘要

DESCRIPTION (provided by applicant): The eighth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, immunology, eukaryotic cell biology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens and the re-ascent of common pathogens. The meeting will provide an in depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major themes of microbial pathogenesis and the host response: how microbes adhere to host cells; the function and delivery of microbial "effectors" of disease; the relationships between microbial metabolism, virulence, and the host; pathogen reservoirs and transmission to the host; the evolution of host-pathogen relationships; and how the host immune system reacts to microbial pathogens;. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-4 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (300 - 400 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from younger investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are difficult to integrate. The resulting interdisciplinary interactions will yield novel experimental approaches that might not otherwise be possible. PUBLIC HEALTH RELEVANCE: Microbial infectious diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens and the re-ascent of common pathogens. The proposed conference on Microbial Pathogenesis and Host Response will focus on the latest approaches to study and treat these devastating diseases, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genome science. The integration of a wide variety of aspects of bacterial and fungal disease mechanisms together with an improved understanding of the host's response to these pathogens should promote new interdisciplinary interactions seldom achieved at other meetings on microbial pathogenesis. These interactions are anticipated to yield novel experimental approaches, paradigms, diagnostics and therapies.

描述（由申请人提供）：第八届微生物发病机制和宿主反应国际会议将重点关注研究传染病的跨学科方法，整合分子微生物学、免疫学、真核细胞生物学和基因组学等学科。由于新病原体的出现和常见病原体的重新崛起，微生物疾病再次在全球医疗保健中发挥重要的核心作用。会议将深入关注用于阐明细菌和真菌发病机制的方法，并促进这些概念在控制和干预传染病的新策略中的应用。口头和海报会议将重点关注微生物发病机制和宿主反应的主要主题：微生物如何粘附到宿主细胞；疾病微生物“效应器”的功能和传递；微生物代谢、毒力和宿主之间的关系；病原体储存库和向宿主的传播；宿主与病原体关系的演变；以及宿主免疫系统如何对微生物病原体做出反应；。这些会议将整合细菌和真菌病原体的研究。口头会议将首先由该领域的知名领导者进行 2-4 场受邀演讲，然后是从提交的摘要中选出的几场较短的演讲。两次海报会议以及每次演讲后分配充足的时间提问将鼓励参与者之间进行广泛的讨论。会议规模足够小（300 - 400 名科学家）以促进这些互动，但又足够大，不仅可以让资深研究人员进行口头陈述，还可以让年轻的研究人员和具有新颖观点的研究人员进行口头陈述。将细菌和真菌发病机制的各个方面与宿主对病原体的反应相结合，应该会促进新的跨学科互动，而这种互动在其他有关微生物发病机制的会议上很少实现，这些会议要么关注范围更窄，要么过于多样化，以至于主题难以整合。由此产生的跨学科互动将产生原本不可能实现的新颖的实验方法。公共卫生相关性：由于新病原体的出现和常见病原体的重新崛起，微生物传染病再次在全球卫生保健中发挥重要的核心作用。拟议的微生物发病机制和宿主反应会议将重点关注研究和治疗这些破坏性疾病的最新方法，整合分子微生物学、真核细胞生物学、免疫学和基因组科学等学科。细菌和真菌疾病机制的各个方面的整合以及对宿主对这些病原体的反应的更好的理解应该促进新的跨学科互动，这在其他微生物发病机制会议上很少实现。这些相互作用预计将产生新的实验方法、范例、诊断和治疗。