CSHL 2023 Mechanisms of Metabolic Signaling Conference

CSHL 2023代谢信号机制会议

• 批准号: 10751346
• 负责人: DAVID J. STEWART
• 金额: $ 2万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-15 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10751346
• 关键词: Area; Atmosphere; Basic Science; Biochemistry; Blood Circulation; Cardiovascular Diseases; Cell Proliferation; Cells; Clinical; Clinical Research; Collaborations; Data; Dedications; Development; Diabetes Mellitus; Discipline; Disease; Disparate; Emerging Technologies; Ensure; Environment; Equity; Faculty; Family; Fostering; Future; Genome; Geography; Goals; Homeostasis; Hormones; Hybrids; Industrialization; International; Laboratories; Lead; Length of Stay; Life; Malignant Neoplasms; Mammals; Metabolic; Metabolic Control; Metabolic Diseases; Metabolic Pathway; Metabolism; Methodology; Molecular Biology; Mutation; Nutrient; Obesity; Oral; Organ; Organism; Participant; Pathway interactions; Persons; Physiology; Play; Postdoctoral Fellow; Process; Published Comment; Reagent; Regulation; Research Personnel; Role; Schedule; Scientist; Signal Transduction; System; Time; Travel; Woman; Work; cancer cell; cell type; climate change; environmental change; epigenome; field study; graduate student; innovation; insight; interest; laboratory facility; meetings; metabolic abnormality assessment; novel; pandemic disease; posters; preference; symposium; technology platform; unpublished works; virtual

Cold Spring Harbor Laboratory Conference on Mechanisms of Metabolic Signaling May 16 – 20, 2023 Project Summary This proposal seeks support for the meeting on “Mechanisms of Metabolic Signaling” to be held at Cold Spring Harbor Laboratory in May 16 - 20, 2023. The meeting will assemble leaders in the field, together with junior faculty, postdoctoral fellows and graduate students, to discuss the latest advances in our understanding of metabolic regulation and its role in normal physiology as well as a variety of disease states ranging from obesity to cancer. Metabolic processes are required for life, and are remarkably similar from organism to organism and from cell to cell. In mammals, specific cell types use metabolic pathways in highly specialized ways to conduct their cell-specific functions. Further, the specialized function of some cell types serves to maintain metabolic homeostasis of the, multicellular organism by regulating levels of hormone and metabolite messengers in the bloodstream. Metabolic diseases such as obesity and diabetes result when those processes fail. At the same time, cancer is increasingly recognized as a state whereby the malignant cell proliferates by altering its fuel metabolism and ignoring metabolic signals. The meeting will cover a broad spectrum of topics ranging from Metabolic Crosstalk with Genome and Epigenome to Interorgan Crosstalk and Nutrient Utilization. In addition, one session is dedicated to Emerging Technologies in the field. Each session will be chaired by a leading scientist in the field. Oral presentations will be given by a group of distinguished invited speakers as well as speakers selected from submitted abstracts. Selected speakers will include graduate students, postdoctoral fellows and junior faculty aiming for maximal inclusion of young investigators. Of special importance are the two poster sessions, where many participants can present their work in an atmosphere conducive to informal discussion. The meeting will be of moderate size, and we expect about 250 people to attend, the vast majority of whom will be presenting a poster or talk. Session chairs and presenters will be required to attend in-person to ensure a critical mass of attendees gathering at Cold Spring Harbor; however, we will facilitate an additional virtual audience layered on top of the in person attendance. This will be important both because travel concerns are likely to persist for some time after the pandemic, and because, looking to the future, virtual attendance at meetings will help to reduce the effects of scientific conferences on climate change and enable more equitable participation from labs around the world.

冷春港实验室会议 代谢信号的机理 5月16日至20日，2023年 项目摘要 该建议寻求支持“代谢信号机制”的会议 2023年5月16日至2033日在冷泉港实验室举行。会议将组成领导人 在现场，与初级教师，博士后研究员和研究生一起讨论 我们了解代谢调节及其在正常生理学中的作用的最新进展 以及从肥胖到癌症的各种疾病状态。 代谢过程是生命所需的，并且从生物体到生物非常相似 并从细胞到细胞。在哺乳动物中，特定细胞类型在高度专业化的 进行其细胞特异性功能的方法。此外，某些单元类型的专业功能 通过调节水平来维持多细胞生物的代谢稳态 血液中的激素和代谢物使者。肥胖等代谢疾病 当这些过程失败时，会导致糖尿病。同时，癌症越来越多 被公认为恶性细胞通过改变其燃料代谢和 忽略代谢信号。 这次会议将涵盖各种各样的主题，从代谢串扰与基因组 和表观基因组到间跨串扰和营养利用率。此外，一个会话是 致力于该领域的新兴技术。每个会议将由领导的主持人主持 该领域的科学家。口头演示将由一组杰出的邀请发言人进行 以及从提交摘要中选择的演讲者。选定的演讲者将包括研究生 学生，博士后研究员和初级教职员工，旨在最大程度地纳入年轻人 调查人员。两个海报会议特别重要，许多参与者可以在这里 在氛围中介绍他们的作品，以进行非正式讨论。会议将是 适度的规模，我们希望大约250人参加，其中绝大多数将会 呈现海报或谈话。会议椅子和主持人将被要求面对面 确保大量的参与者聚集在冷泉港；但是，我们将促进 额外的虚拟观众在同时出席的基础上分层。这将很重要 因为旅行的关注可能会在大流行之后持续一段时间，因为 展望未来，虚拟参加会议将有助于减少科学的影响 关于气候变化的会议，并从周围的实验室获得更公平的参与 世界。