CSHL 2023 Conference on Microbial Pathogenesis & Host Response

CSHL 2023微生物发病机制会议

• 批准号: 10675902
• 负责人: DAVID J. STEWART
• 金额: $ 0.75万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-13 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10675902
• 关键词: Amphibia; Antibiotics; Biological; Biology; COVID-19 pandemic; Cells; Cellular biology; Chiroptera; Chronic; Chronic Disease; Communicable Diseases; Communities; Development; Diagnostic; Discipline; Disease; Ecosystem; Ensure; Environment; Eukaryotic Cell; Evolution; Faculty; Genetic Diseases; Genomics; Goals; HIV; Health; Healthcare; Heart Diseases; Human; Image; Immune; Immune response; Immunocompromised Host; Immunology; Individual; Industrialization; Infection; Infection Control; Influentials; Innate Immune Response; International; Intervention; Laboratories; Learning; Malignant Neoplasms; Medical Device; Metabolic; Microbe; Microbial Antibiotic Resistance; Microbial Biofilms; Microbiology; Molecular; Molecular Genetics; Natural Immunity; Oral; Participant; Pathogenesis; Postdoctoral Fellow; Primary Infection; Recording of previous events; Regulation; Research; Research Personnel; Resistance; Role; Scientist; Surface; Technology; Time; Toxin; Ulcer; Vaccines; Visualization; War; antimicrobial; commensal microbes; dysbiosis; emerging pathogen; extensive drug resistance; genome sciences; graduate student; host-microbe interactions; human disease; human mortality; improved; insight; interdisciplinary approach; meetings; member; microbial; microbial community; microbial disease; next generation; novel; novel strategies; pandemic disease; pathogen; pathogenic bacteria; pathogenic fungus; pathogenic microbe; patient population; posters; professor; programs; skills; symposium; tool; vaccine development

Microbial Pathogenesis and Host Response September 11 – 15, 2023 ABSTRACT The fourteenth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens, the re-ascent of common pathogens, and extensive drug resistance. Outside of human health, devastating pandemics are destabilizing ecosystems, with brown bats and amphibians currently under extreme threat. The meeting will provide an in- depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major emerging themes of microbial pathogenesis and the host response, including: the pathogenesis of microbial diseases; the molecular regulation of host- pathogen interactions, host cell/pathogen interaction biology, and the diversity of pathogen strategies to evade innate immunity. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-3 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. Broad themes for individual sessions include: (1) role of microbial toxins and effectors in microbial diseases; (2) fundamental cell biological interactions during infection, (3) innate immune responses to microbial infection’ (4) key molecular regulation of host-microbial interactions; (5) microbial communities in health and disease, and (6) using state-of-the art technologies to visualize host-pathogen interactions. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (250-350 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from junior investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are challenging to integrate. The resulting interdisciplinary interactions will facilitate the development of conceptual and experimental approaches that might not otherwise be possible.

微生物发病机理和宿主反应 9月11日至15日，2023年 抽象的 第十四届微生物发病机理和宿主反应国际会议将重点放在 研究传染病的跨学科方法，整合了分子微生物学的学科， 真核细胞生物学，免疫学和基因组学。微生物疾病再次采取了重要的 由于新病原体的出现，全世界的核心角色在全球范围内重新出现 病原体和广泛的耐药性。在人类健康之外，毁灭性的大流行者正在不稳定 生态系统，棕色蝙蝠和两栖动物目前受到极端威胁。会议将提供一个 深度专注于用于阐明细菌和真菌机制的方法 发病机理，并促进这些概念在控制和干预的新型策略中的应用 传染病。口腔和海报会议将集中于主要的微生物发病机理的主要主题 和宿主反应，包括：微生物疾病的发病机理；宿主的分子调节 病原体相互作用，宿主细胞/病原体相互作用生物学以及逃避病原体策略的多样性 先天免疫。课程将整合细菌和真菌病原体的研究。口头会议将 从该领域的成熟领导人开始的2-3次邀请会谈开始，然后从中选择了几次较短的演讲 提交的摘要。各个会话的广泛主题包括：（1）微生物毒素的作用和影响 微生物疾病； （2）感染过程中基本细胞生物学相互作用，（3）先天免疫反应 微生物感染”（4）宿主 - 微生物相互作用的关键分子调节； （5）健康中的微生物社区 和疾病，以及（6）使用最先进的技术可视化宿主病原体相互作用。包括 每次谈话之后的两个海报会议以及分配充足的时间进行问题会鼓励 参与者之间的广泛讨论。会议将足够小（250-350个科学家）来促进 这些相互作用，但足够大，不仅允许口头陈述 也来自初级调查人员和具有新颖观点的研究人员。各个方面的整合 细菌和真菌发病机理对病原体的宿主反应应促进新的跨学科 在其他关于微生物发病机理的会议上很少实现的相互作用，这要么狭窄 专注于或如此多样化，主题是集成的挑战。由此产生的跨学科互动将 促进概念和实验方法的发展，这些方法可能是不可能的。