CSHL 2019 Microbial Pathogenesis and Host Response Conference

CSHL 2019微生物发病机制与宿主反应会议

基本信息

批准号：
9761646
负责人：
DAVID J. STEWART
金额：
$ 0.7万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2020-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9761646
关键词：
Amphibia Antibiotics Biological Biology Cells Cellular biology Chiroptera Chronic Chronic Disease Communicable Diseases Communities Development Diagnostic Discipline Disease Disease Outcome Ecology Ecosystem Ensure Environment Eukaryotic Cell Evolution Faculty Food Genetic Diseases Genomics Goals Government HIV Health Healthcare Heart Diseases Heterogeneity Human Immune Immune response Immunocompromised Host Immunology Incidence Individual Industrialization Infection Infection Control Influentials International Intervention Laboratories Learning Malignant Neoplasms Medical Device Metabolic Microbe Microbial Antibiotic Resistance Microbial Biofilms Microbiology Molecular Molecular Genetics Natural Immunity Oral Participant Pathogenesis Postdoctoral Fellow Primary Infection Recording of previous events Regulation Research Research Personnel Resistance development Role Scientist Surface Time Ulcer Vaccines Virulence War antimicrobial co-infection commensal microbes dysbiosis extensive drug resistance gastrointestinal genome sciences graduate student human disease human mortality improved insight interdisciplinary approach meetings member microbial microbial disease microbial host next generation novel novel strategies pandemic disease pathogen pathogenic bacteria pathogenic fungus pathogenic microbe patient population posters professor programs skills symposium tool vaccine development

项目摘要

Microbial Pathogenesis and Host Response September 10 - 14, 2019 The twelfth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens, the re-ascent of common pathogens, and extensive drug resistance. Outside of human health, devastating pandemics are destabilizing ecosystems, with brown bats and amphibians currently under extreme threat. The meeting will provide an in- depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major emerging themes of microbial pathogenesis and the host response, including: the pathogenesis & evolution of microbial diseases; the regulation of pathogenesis, heterogeneity of pathogens as an adaptive mechanism, host cell/pathogen interactions, and the diversity of pathogen strategies to evade innate immunity. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-3 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. Broad themes for individual sessions include: 1) pathogen coinfections; 2) cell biology of infections; 3) heterogeneity in pathogen and disease outcomes; 4) the diversity of pathogen evasion strategies of innate immunity; 5) microbial evolution and virulence; and 6) gastrointestinal ecology and microbial pathogenesis. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (300 - 400 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from junior investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are challenging to integrate. The resulting interdisciplinary interactions will facilitate the development of conceptual and experimental approaches that might not otherwise be possible.

微生物发病机理和宿主反应 2019年9月10日至14日第十二届微生物发病机理和宿主反应的国际会议将重点放在研究传染病的跨学科方法，整合了分子微生物学的学科，真核细胞生物学，免疫学和基因组学。微生物疾病再次采取了重要的由于新病原体的出现，全世界的核心角色在全球范围内重新出现病原体和广泛的耐药性。在人类健康之外，毁灭性的大流行者正在不稳定生态系统，棕色蝙蝠和两栖动物目前受到极端威胁。会议将提供一个深度专注于用于阐明细菌和真菌机制的方法发病机理，并促进这些概念在控制和控制策略中的应用传染病的干预。口头和海报会议将集中于主要的微生物主题发病机理和宿主反应，包括：微生物疾病的发病机理和进化；这调节发病机理，病原体的异质性作为一种自适应机制，宿主细胞/病原体相互作用，以及逃避先天免疫力的病原体策略的多样性。会议将集成细菌和真菌病原体的研究。口头会议将以2-3的邀请会谈开始该领域的领导者，随后从提交的摘要中选择了几次简短的演讲。广泛的主题各个会议包括：1）病原体共感染； 2）感染的细胞生物学； 3）病原体的异质性和疾病结果； 4）病原体逃避先天免疫的多样性； 5）微生物进化和毒力； 6）胃肠道生态学和微生物发病机理。包括两个海报会议以及每次谈话之后提问的充足时间的分配将鼓励参与者之间的广泛讨论。会议将足够小（300-400位科学家）促进这些互动，但足够大，不仅可以从已建立的研究人员，也来自初级调查人员和具有新颖观点的研究人员。宽阔的整合细菌和真菌发病机理的各种方面以及对病原体的宿主反应应促进在其他关于微生物发病机理的会议上很少实现的新的跨学科互动要么更狭窄，要么是如此多样化，以至于主题具有挑战性。结果跨学科的互动将促进概念和实验方法的发展否则可能是不可能的。