Perceived Fairness and Biological Stress Reactivity

感知公平性和生物应激反应

基本信息

批准号：
8128637
负责人：
Todd William Lucas
金额：
$ 15.2万
依托单位：
WAYNE STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-08-15 至 2013-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8128637
关键词：
Adherence Affect African American Arousal Belief Benchmarking Biological Biological Markers C-reactive protein Cardiovascular Diseases Cardiovascular system Clinical Communities Data Dehydroepiandrosterone Sulfate Discrimination Disease Environment Evaluation Experimental Designs Goals Health Health Resources Hydrocortisone Incidence Individual Individual Differences Inflammatory Interdisciplinary Study Intervention Judgment Justice Knowledge Laboratories Link Literature Measurement Measures Mediator of activation protein Methodology Methods Minority Groups Modeling Outcome Outcomes Research Pathway interactions Play Prevention Process Public Health Research Research Methodology Research Personnel Resources Risk Factors Role Sampling Source Stress Testing Trier Social Stress Test Triglycerides Work base biological adaptation to stress blood lipid clinically significant design ethnic minority population health disparity hemodynamics high risk innovation novel psychosocial public health relevance racism stem success trait

项目摘要

DESCRIPTION (provided by applicant): Beliefs about fairness are a clinically significant predictor of cardiovascular health. Fairness beliefs are fundamentally important to cardiovascular health through their capacity to impact biological stress processes. However, the extent to which specific kinds of fairness beliefs influence important biological stress pathways is largely unknown. Ultimately, these limitations have impeded the capacity of researchers to better understand how fairness is implicated in cardiovascular illness, and also to evaluate fairness-oriented cardiovascular interventions. The long-term goal of this research is to elucidate the role played by fairness in cardiovascular health, and to determine whether fairness is a common causal process linking such other risk factors as racism, low SES, and work stress to subsequent biological mediators of cardiovascular illness. The objective of this application is to experimentally elucidate relationships between specific measurements of fairness beliefs and multiple biological stress pathways. The central hypothesis of this application is that procedural and distributive fairness will independently and interdependently predict more adaptive biological stress reactivity. In addition, we expect that these relationships will be reflected in both trait dispositions and situational judgments of fairness, and also in multiple biological and disease relevant stress pathways. The specific aims are to 1) measure the unique and interactive contributions of distributive (favorable outcomes) and procedural (treatment by others) fairness on biological stress reactivity; 2) measure the unique and interactive contributions of dispositional (trait) and situationally induced (state) fairness on biological stress reactivity; 3) measure relationships between fairness beliefs and important biological stress pathways, including markers of hemodynamic reactivity, HPA axis arousal, and pro-inflammatory processes. The proposed research will administer a modified version of a well established and laboratory-based stress induction paradigm. In doing so, this research will experimentally evaluate associations between specific kinds of fairness beliefs and multiple biological stress pathways. The public health implication of the project is significant. Namely, the proposed research will provide an important step towards defining disease relevant models, and for targeting and evaluating psychosocial interventions. PUBLIC HEALTH RELEVANCE: Beliefs about fairness predict both stress reactivity and incidence of cardiovascular illness. The proposed research will use experimental methodologies to assess independent and interdependent effects of multiple kinds of fairness beliefs on biological stress processes. The proposed research will carry important public health implications by elucidating the role of unique sources of fairness beliefs in important stress pathways, and by suggesting causal links between fairness and cardiovascular health.

描述（由申请人提供）：关于公平性的信念是心血管健康的临床重要预测指标。公平信念通过影响生物压力过程的能力而对心血管健康至关重要。但是，特定种类的公平信念影响重要的生物压力途径的程度在很大程度上是未知的。最终，这些局限性阻碍了研究人员更好地了解公平与心血管疾病的影响，并评估面向公平性的心血管干预措施。这项研究的长期目标是阐明公平在心血管健康中所扮演的角色，并确定公平是将种族主义，低SES和工作压力与随后的心血管疾病生物学调解人等其他风险因素联系起来的常见因果过程。该应用的目的是实验阐明公平信念的特定测量和多种生物压力途径之间的关系。该应用的中心假设是程序和分配公平性将独立和相互依存地预测更适应性的生物应力反应性。此外，我们期望这些关系将反映在公平性的性格处置和情境判断中，也可以反映在多种生物学和疾病相关的压力途径中。具体目的是1）衡量分布式（有利的结果）和程序（其他人的治疗）对生物压力反应性的公平性的独特和互动贡献； 2）衡量处置（性状）和情境引起的（状态）公平性的独特和互动贡献； 3）衡量公平信念与重要的生物压力途径之间的关系，包括血液动力学反应性的标志，HPA轴的唤醒和促炎过程。拟议的研究将管理建立良好且基于实验室的压力诱导范式的修改版本。为此，这项研究将在实验上评估特定种类的公平信念与多种生物压力途径之间的关联。该项目的公共卫生影响很大。也就是说，拟议的研究将为定义疾病相关模型以及针对和评估社会心理干预措施提供重要的一步。公共卫生相关性：关于公平性的信念可以预测压力反应性和心血管疾病的发生率。拟议的研究将使用实验方法来评估多种公平信念对生物压力过程的独立和相互依存的影响。拟议的研究将通过阐明公平信念在重要的压力途径中的独特来源的作用，并提出公平与心血管健康之间的因果关系来具有重要的公共卫生影响。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Positive and negative affectivity, stress, and well-being in African-Americans: Initial demonstration of a polynomial regression and response surface methodology approach.

非裔美国人的积极和消极情感、压力和幸福感：多项式回归和响应面方法的初步演示。

DOI：
10.1080/08870446.2017.1368510
发表时间：
2018
期刊：
Psychology & health
影响因子：
3.3
作者：
Pierce,Jennifer;Zhdanova,Ludmila;Lucas,Todd
通讯作者：
Lucas,Todd

Reactivity of salivary uric acid in response to social evaluative stress in African Americans.

非裔美国人唾液尿酸对社会评价压力的反应性。

DOI：
10.1016/j.biopsycho.2020.107882
发表时间：
2020
期刊：
Biological psychology
影响因子：
2.6
作者：
Lucas,Todd;Riis,JennaL;Buchalski,Zachary;Drolet,CarolineE;Dawadi,Anurag;Granger,DouglasA
通讯作者：
Granger,DouglasA

Salivary uric acid: Associations with resting and reactive blood pressure response to social evaluative stress in healthy African Americans.

唾液尿酸：与健康非裔美国人的静息血压和反应性血压对社会评价压力的反应相关。

DOI：
10.1016/j.psyneuen.2018.10.025
发表时间：
2019
期刊：
Psychoneuroendocrinology
影响因子：
3.7
作者：
Woerner,Jacqueline;Lucas,Todd;Pierce,Jennifer;Riis,JennaL;Granger,DouglasA
通讯作者：
Granger,DouglasA

Justice for all? Beliefs about justice for self and others and telomere length in African Americans.

为所有人伸张正义？

DOI：
10.1037/cdp0000212
发表时间：
2018
期刊：
Cultural diversity & ethnic minority psychology
影响因子：
3.3
作者：
Lucas,Todd;Woerner,Jacqueline;Pierce,Jennifer;Granger,DouglasA;Lin,Jue;Epel,ElissaS;Assari,Shervin;Lumley,MarkA
通讯作者：
Lumley,MarkA

Perceived racism, affectivity, and C-reactive protein in healthy African Americans: Do religiosity and racial identity provide complementary protection?