Enhanced Medication Management to Control ADRD Risk Factors Among African Americans and Latinos

加强药物管理以控制非裔美国人和拉丁裔的 ADRD 风险因素

基本信息

批准号：
10610975
负责人：
Alvin Ramsey
金额：
$ 29.96万
依托单位：
PILLTRAX SYSTEMS LLC
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-18 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10610975
关键词：
Address Adherence Adoption Affect African American African American population Age Years Algorithms Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Alzheimer&apos s disease risk Antidiabetic Drugs Antihypertensive Agents Caring Categories Communities Data Diabetes Mellitus Disparity Early Diagnosis Early Intervention Elderly Electronics Expenditure Feedback Future Goals Hispanic Populations Hypertension Latino Latino Population Logistic Regressions Machine Learning Medical Medication Management Minority Morbidity - disease rate Movement Notification Participant Patients Pharmaceutical Preparations Phase Provider Recommendation Recording of previous events Risk Risk Factors Risk Management Risk Reduction Services Surveys System Testing Time Training United States Agency for Healthcare Research and Quality Visit algorithm training caucasian American cloud platform dementia risk design empowerment improved innovation interest medication compliance patient population pill prediction algorithm predictive modeling predictive tools provider portal random forest success trend

项目摘要

Project Summary/Abstract Alzheimer’s disease and related dementias (ADRD) disproportionately affects minorities – African Americans are 2x more likely and Hispanics/Latinos are 1.5x more likely than white Americans to have ADRD. Recently, the Alzheimer’s Impact Movement (AIM) and the Alzheimer’s Association supported the recommendation of “better management of risk factors – particularly high blood pressure and diabetes – to reduce the risk of ADRD among African Americans and Hispanics/Latinos.” Medications can be very effective in managing both hypertension and diabetes, but unfortunately adherence to these medications is commonly low, particularly among African Americans and Hispanics/Latinos. Marginal adherence (60%-80%) with anti-hypertensive medication is inadequate because these patients still had significantly elevated risks (3x greater compared to fully adherent, 2.5x greater compared to highly adherent) of developing ADRD. Hence, an effective pro-active solution for optimizing medication adherence can positively impact this patient population. The proposed solution will be a medication management service designed for providers. The full solution would comprise of: (A) a commercially available electronic pill dispenser that sends SMS notifications of pills taken/missed, (B) future adherence assessment based on historical data, and (C) a provider portal which presents adherence-related information. To address the disparity in ADRD among African Americans and Latinos, the initial implementation will specifically focus on providers who deliver care to older adults in these communities.

项目摘要/摘要阿尔茨海默氏病和相关痴呆症（ADRD）不成比例地影响少数群体 - 非洲裔美国人是2倍与白人美国人相比，西班牙裔/拉丁美洲人的可能性更高1.5倍。最近，阿尔茨海默氏症影响运动（AIM）和阿尔茨海默氏症协会支持“更好地管理风险的建议因素，尤其是高血压和糖尿病的因素，以降低非裔美国人和西班牙裔/拉丁裔。”药物可以在管理高血压和糖尿病方面非常有效，但不幸的是遵守这些药物通常很低，尤其是在非裔美国人和西班牙裔/拉丁美洲人中。边缘抗高血压药物的依从性（60％-80％）不足，因为这些患者仍然有明显的发展ADRD的风险升高（与完全粘附的相比相比，比完全粘附的人要高2.5倍）。因此，一种有效优化药物依从性的积极活跃解决方案可以对该患者产生积极影响人口。拟议的解决方案将是为提供者设计的药物管理服务。完整的解决方案将由：（a）商业可用的电子药丸分配器，该分配器发送/错过的药丸通知，（b）基于历史数据的未来依从性评估，以及（c）提供与依从性相关的提供商门户信息。为了解决非裔美国人和拉丁美洲人的ADRD差异，最初的实施将特别是专注于为这些社区中老年人提供照顾的提供者。