Head and Neck Cancer Immunology Administrative Core

头颈癌免疫学行政核心

• 批准号: 10020928
• 负责人: Sara Isabel Pai
• 金额: $ 13.53万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-19 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10020928
• 关键词: Advisory Committees; Advocate; Budgets; Cancer Center; Clinical; Collaborations; Communication; Communities; Consultations; Dana-Farber Cancer Institute; Diagnostic; Ensure; Evaluation; Evaluation Research; Fostering; Funding; General Hospitals; Goals; Grant; Group Meetings; Head and Neck Cancer; Immune; Immune Targeting; Immunotherapeutic agent; Lead; Manuscripts; Massachusetts; Methods; Monitor; Outcome; Patients; Performance; Pre-Clinical Model; Preparation; Publications; Research; Research Project Grants; Resource Sharing; Resources; Scientist; Suggestion; Testing; Therapeutic; Therapeutic Agents; Translating; Translations; Validation; base; clinical translation; combinatorial; head and neck cancer patient; immune resistance; improved; innovation; meetings; novel; novel therapeutics; programs; synergism; targeted treatment; tumor immunology

SUMMARY – ADMINISTRATIVE CORE The purpose of the Program Administration Core is to provide support for the Integrated Program on “Strategies to Overcome Immune Resistance in Head and Neck Cancers.” The Core Director (Dr. Pai) and co-Director (Dr. Wirth) will provide guidance and oversight to the Projects and shared Cores and will lead the evaluation of research progress including consultation with Internal and External Advisory Boards. The Administration Core will coordinate the inter-related complementary research projects to maximize their scientific synergy and to share the findings with the broader scientific and clinical communities. The Core will provide assistance to Projects, including administrative support, regular project review meetings, support for manuscript preparation, project evaluation, and scientific communication. The ultimate goal of the Program is to translate immune based discovery into new therapies for patients with head and neck cancer through the testing and validation of novel therapeutic agents in preclinical models prior to its translation into patients.

摘要——行政核心 计划管理核心的目的是为综合计划提供支持 “克服头颈癌免疫抵抗的策略。”核心主任（博士） Pai）和联合主任（Wirth 博士）将为项目和共享核心提供指导和监督 并将领导研究进展的评估，包括与内部和外部的协商 行政核心将协调相互关联的补充研究。 项目，以最大限度地发挥其科学协同作用，并与更广泛的科学和领域分享研究结果 核心将为项目提供援助，包括行政支持、 定期举行项目评审会议，为稿件准备、项目评估和科学性提供支持 该计划的最终目标是将基于免疫的发现转化为新的发现。 通过测试和验证新疗法来治疗头颈癌患者 临床前模型中的治疗剂在转化为患者之前。