Core A: Administrative Core

核心A：行政核心

• 批准号: 10264623
• 负责人: RUSSELL H. SWERDLOW
• 金额: $ 50.57万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10264623
• 关键词: Address; Advisory Committees; Advocate; Alzheimer' s Disease; Alzheimer' s disease related dementia; Area; Automobile Driving; Budgets; Clinical; Clinical Trials; Consent; Consultations; Data; Development; Education; Ensure; Faculty; Fund Raising; Funding; Genomics; Goals; Government; Grant; Growth; Infrastructure; Intervention Studies; Kansas; Metabolism; Mitochondria; Molecular; Monitor; Patient Care; Pilot Projects; Play; Prevention Research; Prevention strategy; Productivity; Program Development; Progress Reports; Public Relations; Research; Research Personnel; Resources; Role; Services; Site Visit; Strategic Planning; United States National Institutes of Health; Universities; Visit; Work; aging brain; base; design; effective therapy; empowered; falls; lifestyle intervention; meetings; mitochondrial metabolism; neuroimaging; operation; programs; ranpirnase; recruit; success; symposium; treatment strategy

ABSTRACT: ADMINISTRATIVE CORE The Administrative Core oversees operational and strategic planning for the University of Kansas Alzheimer's Disease Research Center (KU ADRC). Over a decade of P30 support, the Core managed growth that saw us become a leader in AD mitochondria/metabolism, lifestyle intervention, and prevention research. Supporting these programs required us to develop and implement unique infrastructure that promotes specialized molecular, clinical trial, recruitment, education, and patient care initiatives. In addition to defining Center strategy, the Core manages the resources needed to support our investigators. This includes biospecimen procurement plans; consent and compliance requirements; ensuring biospecimen storage; and facilitating access to biospecimens, data, consultation, and other Center services. We advise our other cores, monitor their productivity, and promote their seamless and synergistic cooperation. We verify NIA programmatic obligations are efficiently met and maintain Internal and External Advisory Committees. Up to this point we ran an immensely successful pilot project program; from 2011 through 2019 we saw 27 of 40 (68%) of our pilot recipients receive external grant support. The Core ensures all KU ADRC components receive adequate financial resources. Beyond managing our P30 budget, we accomplish this by identifying and procuring dollars from institutional ADRC stakeholders, developing philanthropy, and submitting P30 supplements. Whether designing strategy, tracking down dollars, identifying space, building resources, developing investigators, or growing the Center and advancing its agenda, the Administrative Core plays an integral role in both short-and-long term KU ADRC successes. Over the past 10 years we clearly transformed AD, AD-related, and brain aging research at the University of Kansas. During our next cycle we will continue our trajectory of guided, strategic growth that advances the AD research field and moves us closer to effective treatments and prevention strategies. We will accomplish these goals by focusing on a defined set of specific aims that include: (1) Managing infrastructure and routine operations; (2) Developing and empowering intellectual assets; and (3) Defining goals and amplifying impact.

摘要：行政核心 行政核心负责监督堪萨斯大学的运营和战略规划 阿尔茨海默病研究中心 (KU ADRC)。经过十多年的 P30 支持，核心管理了增长 这使我们成为 AD 线粒体/代谢、生活方式干预和预防研究领域的领导者。 支持这些计划需要我们开发和实施独特的基础设施，以促进 专门的分子、临床试验、招募、教育和患者护理计划。 除了定义中心战略外，核心还管理支持我们的资源所需的资源 调查人员。这包括生物样本采购计划；同意和合规要求；确保 生物样本储存；促进获得生物样本、数据、咨询和其他中心服务。 我们为其他核心提供建议，监控他们的生产力，并促进他们的无缝和协同合作。 我们验证 NIA 计划义务是否得到有效履行并维持内部和外部咨询 委员会。到目前为止，我们已经运行了一个非常成功的试点项目；从 2011 年到 2019 年 我们发现 40 名试点受益人中有 27 名 (68%) 获得了外部赠款支持。核心确保所有 KU ADRC 各组成部分获得充足的财政资源。除了管理 P30 预算之外，我们还通过以下方式实现这一目标： 确定 ADRC 机构利益相关者并获取资金，发展慈善事业，并提交 P30补充剂。 无论是设计战略、追踪资金、确定空间、建设资源、开发 调查员，或发展中心并推进其议程，行政核心在以下方面发挥着不可或缺的作用： KU ADRC 短期和长期的成功。在过去的10年里，我们明确地改变了AD、AD相关的、 以及堪萨斯大学的大脑衰老研究。在下一个周期中，我们将继续我们的轨迹 引导性、战略性的增长，推动 AD 研究领域的发展，使我们更接近有效的治疗方法和 预防策略。我们将通过专注于一组明确的具体目标来实现这些目标 包括： (1) 管理基础设施和日常运营； (2) 智力开发和赋权 资产; (3) 明确目标并扩大影响。