Help Us, Save Us! HIV/STI Prevention Intervention for High-Risk Black Men

帮助我们，拯救我们！

• 批准号: 7798598
• 负责人: JOHN BARTON JEMMOTT
• 金额: $ 66.65万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-13 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7798598
• 关键词: AIDS/HIV problem; Address; Affect; African American; Alcohols; Anus; Behavior; Behavior Therapy; Behavioral; Belief; Cities; Clinical Trials Design; Communities; Drug usage; Educational workshop; Focus Groups; Frequencies; Fright; Funding; HIV; Health; Health Promotion; Incidence; Infection prevention; Intention; Intervention; Longitudinal Surveys; Mediation; Modeling; Multiple Partners; Participant; Philadelphia; Planning Theory; Population; Population Study; Prevention; Preventive Intervention; Public Health; Randomized; Randomized Controlled Trials; Research; Research Personnel; Risk; Risk Reduction; Sexual Health; Sexually Transmitted Diseases; Solid; Testing; Treatment Efficacy; United States; Universities; Vagina; base; community organizations; condoms; consistent condom use; efficacy testing; high risk; intervention effect; man; men; men who have sex with men; post intervention; primary outcome; response; secondary outcome; sex; sex risk; social cognitive theory; theories; therapy development

DESCRIPTION (provided by applicant): The incidence of HIV/AIDS among African American men who have sex with men (MSM) is alarming, and the public health response to this urgent situation has been hampered by a lack of sexual risk reduction interventions with solid evidence of efficacy in this population. Accordingly, the broad, long-term objective of the proposed research is to identify interventions to reduce the risk of sexually transmitted infection (STI) among African American MSM. This is a collaborative effort by HIV/STI university-based researchers and Blacks Educating Blacks About Sexual Health Issues (BEBASHI), the oldest community-based organization (CBO) in the City of Philadelphia that has addressed HIV in the African American community, including MSM. This application seeks funds to develop and test the efficacy of a theory-based, contextually appropriate behavioral intervention to reduce sexual risk behavior among African American MSM. Intervention development will be guided by social cognitive theory, the theory of planned behavior, qualitative information from focus groups, and findings from a longitudinal survey of men from the study population. A one-on-one intervention will be utilized to address the specific prevention needs of each man and to allay participants' concerns about revealing their sexual involvement with men by virtue of participating in a group or workshop intervention. The study will utilize a randomized controlled trial design, with baseline, immediate post intervention, and 6 and 12 months post intervention assessments. The participants will be 594 African American MSM who will be randomized to a one-on-one sexual risk reduction intervention or a one-on-one health promotion intervention that will serve as the control condition. The primary outcome is consistent condom use during anal and vaginal intercourse. The specific aims concern the efficacy of the intervention in increasing consistent condom use during anal intercourse, the primary outcome, and testing the mediation of the effects of the intervention on consistent condom use. This study will provide an urgently needed intervention to reduce the risk of HIV and other STIs in one of the highest risk populations in the United States.

描述（由申请人提供）：与男性发生性关系（MSM）的非洲裔美国男性中的艾滋病毒/艾滋病的发生率令人震惊，并且由于缺乏性风险降低干预措施而缺乏可靠的证据证据，对这种紧急情况的公共卫生反应受到了阻碍。因此，拟议的研究的广泛长期目标是确定干预措施，以降低非裔美国人MSM中性传播感染（STI）的风险。这是基于艾滋病毒/STI大学的研究人员和黑人对黑人进行性健康问题（Bebashi）的合作努力，该问题是费城市最古老的社区组织（CBO），该组织（CBO）在包括MSM在内的非裔美国人社区中对艾滋病毒的介绍。该应用程序寻求资金来开发和测试基于理论的，上下文适当的行为干预以减少非裔美国人MSM的性风险行为的功效。干预发展将由社会认知理论，计划行为理论，焦点小组的定性信息以及研究人群中男性的纵向调查的结果指导。一对一的干预措施将用于满足每个人的特定预防需求，并通过参与团体或讲习班干预措施来揭示参与者对揭示他们与男人的性爱的担忧。该研究将利用随机对照试验设计，基线，立即干预以及干预后的6个月和12个月。参与者将是594名非裔美国人MSM，他们将被随机分配为一对一的性风险降低干预措施或一对一的健康促进干预措施，该干预措施将作为控制条件。主要结果是在肛门和阴道性交期间使用避孕套。具体目的是涉及干预措施在肛门性交，主要结果以及测试干预对一致避孕套使用的影响的介导期间增加一致的避孕套的功效。这项研究将急需干预措施，以降低美国最高风险人群之一的艾滋病毒和其他性传播感染的风险。