Developing and Pilot Testing a Mobile Phone-Based HIV/STI Prevention Intervention

开发和试点测试基于手机的艾滋病毒/性传播感染预防干预措施

基本信息

批准号：
8708923
负责人：
JOHN BARTON JEMMOTT
金额：
$ 53.57万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-27 至 2017-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8708923
关键词：
AIDS prevention AIDS/HIV problem Accounting Address Adopted African African American Age Age-Years Anus Attention Behavior Behavior Therapy Belief Car Phone Centers for Disease Control and Prevention (U.S.)Client Communities Computer Assisted Control Groups Educational workshop Focus Groups Funding HIV HIV Infections HIV/STD Health Promotion Human immunodeficiency virus test Incidence Individual Intervention Intervention Studies Interview Life Literature Longevity Mediating Newly Diagnosed Ownership Participant Patient Self-Report Pattern Pilot Projects Population Prevention Preventive Intervention Process Public Health Publishing Randomized Randomized Controlled Trials Reporting Research Risk Risk Reduction Safe Sex Sex Behavior Sexual Partners Solid Subgroup Target Populations Technology Testing Text Time Treatment Efficacy Unsafe Sex Vagina base behavior change condoms consistent condom use cost effective design effective intervention efficacy testing follow-up health disparity innovation intervention effect man men men who have sex with men primary outcome response screening secondary outcome sex sex risk social cognitive theory tool trend usability

项目摘要

DESCRIPTION (provided by applicant): This proposal is submitted in response to the alarming rates of HIV among young African American men who have sex with men (MSM). The CDC recently reported that between 2006 and 2009, HIV incidence was stable among all populations in the US except young MSM. The overall increase in incidence among young MSM was driven by a 48% increase in HIV infections among young African American MSM. The broad, long-term objective of this research is to identify strategies to reduce the rates of HIV in young African American MSM. This research will take advantage of the men's avid use of mobile phone technology to deliver an innovative intervention to change their sexual risk behavior. The Specific Aims are to: 1) develop an interactive mobile phone-based HIV/STI risk-reduction intervention that is acceptable and feasible to be implemented with African American MSM ages 18 to 24 years; 2) develop an acceptable and feasible text-messaging adjunctive strategy designed to increase its efficacy; 3) pilot test the efficacy of the HIV/STI risk-reductio intervention compared with an attention-control intervention in increasing the proportion of men who report consistent condom use during anal and vaginal intercourse; and 4) pilot test whether the efficacy of the HIV/STI risk-reduction compared with the control intervention is enhanced among men randomized to the tailored text-messaging adjunctive intervention as compared with other men. African American men ages 18 to 24 years who report having anal intercourse with a man in the 2 months prior to screening will be eligible to participate. The intervention and adjunctive strategy will be developed using an iterative process involving focus groups, input from a community advisory board, usability testing, and small-scale pilot testing. Evidence of potential efficacy will be based on a pilot randomized controlled trial involving 180 men with 6-month follow-up. Men will be randomly assigned to the HIV/STI risk-reduction or an attention-control intervention. In addition, they will be randomly assigned to receive or not receive intervention-specific, individually tailored text messages. The approach draws on social cognitive theory and the applicant's Preliminary Studies with the target population. Self-reported consistent condom use, other sexual behaviors, HIV testing, and variables hypothesized to mediate intervention efficacy will be collected via audio-computer-assisted self-interviewing. The use of a mobile phone technology for intervention would allay participants' concerns about revealing their sexual involvement with men by virtue of participating in a group or workshop intervention. If current trends in smartphone use continue, this research has the potential to produce a cost-effective intervention that local, state, or national organizations might offer to their young African American MSM clients. The proposed research has great public health significance because although young African American MSM have some of the highest rates of HIV in the US, there is a paucity of efficacious HIV/STI interventions tailored to them.

描述（由申请人提供）：本提案是针对年轻非裔美国男男性接触者 (MSM) 中艾滋病毒感染率惊人的情况而提交的。美国疾病预防控制中心最近报告称，2006 年至 2009 年间，除年轻男男性接触者外，美国所有人群中的艾滋病毒发病率保持稳定。年轻的非裔美国男男性接触者中艾滋病毒感染率增加了 48%，推动了年轻男男性接触者的发病率总体上升。这项研究的广泛、长期目标是确定降低艾滋病毒感染率的策略年轻的非裔美国男同性恋者。这项研究将利用男性对移动电话技术的热衷使用来提供创新干预措施，以改变他们的性危险行为。具体目标是： 1) 开发一种基于交互式移动电话的 HIV/STI 风险降低干预措施，该干预措施对于 18 至 24 岁的非裔美国 MSM 来说是可接受且可行的； 2）制定可接受且可行的短信辅助策略，旨在提高其功效； 3) 试点测试艾滋病毒/性传播感染风险降低干预措施与注意力控制干预措施相比，在提高肛交和阴道性交期间坚持使用安全套的男性比例方面的效果； 4) 试点测试与对照干预相比，在随机接受定制短信辅助干预的男性中，与其他男性相比，艾滋病毒/性传播感染风险降低的功效是否有所增强。年龄为 18 至 24 岁的非裔美国男性，如果报告在筛查前 2 个月内与男性发生过肛交，就有资格参加。干预和辅助策略将通过涉及焦点小组、社区咨询委员会的意见、可用性测试和小规模试点测试的迭代过程来制定。潜在功效的证据将基于一项随机对照试验，该试验涉及 180 名男性，并进行了 6 个月的随访。男性将被随机分配接受艾滋病毒/性传播感染风险降低组或注意力控制干预组。此外，他们将被随机分配接收或不接收针对干预措施的、单独定制的短信。该方法借鉴了社会认知理论和申请人对目标人群的初步研究。将通过音频计算机辅助自我访谈收集自我报告的持续使用安全套、其他性行为、艾滋病毒检测以及介导干预效果的假设变量。使用移动电话技术进行干预将减轻参与者对通过参加小组或研讨会干预而暴露自己与男性的性关系的担忧。如果当前智能手机使用趋势继续下去，这项研究有可能产生一种具有成本效益的干预措施，地方、州或国家组织可能会向年轻的非裔美国 MSM 客户提供这种干预措施。这项拟议的研究具有重大的公共卫生意义，因为尽管年轻的非裔美国男男性接触者的艾滋病毒感染率是美国最高的，但针对他们量身定制的有效的艾滋病毒/性传播感染干预措施却很少。