Health Promotion for Positives: A Randomized Trial with HIV Positive Black Men

积极健康促进：艾滋病毒阳性黑人男性的随机试验

• 批准号: 8985689
• 负责人: JOHN BARTON JEMMOTT
• 金额: $ 39.91万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-21 至 2018-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8985689
• 关键词: AIDS prevention; AIDS-Related Opportunistic Infections; Adherence; Affect; African American; Age; Aging; Anti-Retroviral Agents; Applications Grants; Attention; Behavior; Behavioral; Blood Pressure; Body mass index; Budgets; Cardiovascular Diseases; Centers for Disease Control and Prevention (U.S.); Chronic; Chronic Disease; Colon Carcinoma; Comorbidity; Complement; Computer Assisted; Control Groups; Couples; Data; Diabetes Mellitus; Diet; Evidence based intervention; Expectancy; Future; General Population; Guidelines; HIV; HIV Infections; HIV Seropositivity; Health; Health Promotion; Health behavior; Highly Active Antiretroviral Therapy; Hour; Hypertension; Individual; Intervention; Interview; Kidney Diseases; Life; Link; Long-Term Effects; Malignant Neoplasms; Malignant neoplasm of prostate; Measures; Mediating; Mediator of activation protein; Medical Records; Morbidity - disease rate; Outcome; Participant; Patient Self-Report; Persons; Physical Fitness; Physical activity; Physiological; Prevention; Prostate; Randomized; Randomized Controlled Trials; Research; Risk; Screening for Prostate Cancer; Self Efficacy; Testing; Time; Treatment Efficacy; United States; Vulnerable Populations; Waist-Hip Ratio; Walking; base; behavior change; comparative efficacy; design; effective therapy; efficacy testing; empowered; experience; fitness; fruits and vegetables; health disparity; high risk; innovation; interest; man; men; mortality; post intervention; primary outcome; racial health disparity; randomized trial; response; screening; sex; social cognitive theory; successful intervention; theories; waist circumference

PROJECT SUMMARY: This application is in response to RFA-MD-12-001, "NIMHD Health Disparities Research (R01)." African American men who are infected with HIV are living longer and are being impacted by the same chronic diseases that affect the general population of African American men over 40. To be sure, African American men, in general, have disproportionately high rates of cardiovascular disease, hypertension, diabetes, kidney disease, and cancer, particularly prostate and colon cancer. However, HIV infection is associated with an increased risk for co-morbidity from chronic diseases. This increased risk is heightened by HIV infection, but also its treatment with certain agents used in highly active antiretroviral therapy (HAART) combinations. Many of these chronic illnesses have behavioral components-risk is influenced by what people do and don't do, their diet, and the amount of physical activity they get. Although the high risk for multiple behavior-linked chronic diseases among HIV-positive individuals has been recognized, there is a lack of evidence-based intervention specifically tailored to their needs. Hence, the broad objective is to reduce the risk of chronic diseases among HIV positive African American men. The Specific Aims are to test the efficacy of a theory- based, contextually appropriate health promotion intervention in inducing positive changes in behaviors linked to risk of chronic diseases among HIV positive African American men age 40 years or older and to identify the theoretical variables that mediate its efficacy. The study will utilize a randomized controlled trial. The participants will be 384 African American HIV positive men age 40 or older who are receiving HAART for HIV. The men will be randomized to a theory-based contextually appropriate health promotion intervention that involves three, 3-hour weekly intervention sessions or an attention-control group. The health promotion intervention will be an adaptation of an intervention based on social cognitive theory integrated with formative research and found to be efficacious in increasing adherence to 5-a-Day diet and physical activity guidelines and prostate cancer screening guidelines in the applicants' preliminary studies. Data will be collected at baseline, immediately post, 3, 6 and 12 months post intervention, which will permit assessment of the short- term and long-term effects of the intervention and whether the intervention's efficacy varies over time. Audio computer-assisted self-interviewing will be used to assess self-reported adherence to physical activity guidelines, 5-a-Day fruit and vegetable guidelines, prostate screening guidelines, and colon cancer screening guidelines and theoretical mediators of behavior change. Objective outcomes will include health-related fitness (6-minute walk test, 1-minute push-up test, 1-minute sit-up test, sit-and-reach test), physiological variables (blood pressure, body mass index, waist circumference, and waist-hip ratio), and prostate and colon cancer screening based on medical record review.

项目摘要： 该应用是响应RFA-MD-12-001，“ NIMHD健康差异研究（R01）”。非洲人 感染了艾滋病毒的美国男性的寿命更长，并且受到同一慢性的影响 影响40岁以上非裔美国人的普通人群的疾病。可以肯定的是，非裔美国人 总体而言，男性的心血管疾病，高血压，糖尿病，肾脏的比例高。 疾病，癌症，特别是前列腺癌和结肠癌。 但是，HIV感染与 慢性病的合并症风险增加。 艾滋病毒感染增加了这种增加的风险，但 它还与高度活性抗逆转录病毒疗法（HAART）组合的某些药物的治疗。 许多 这些慢性疾病中有行为成分风险受到人们所做和不做什么的影响， 他们的饮食以及他们获得的体育锻炼数量。 虽然多种行为链接的高风险 艾滋病毒阳性个体中的慢性疾病已被认可，缺乏基于证据的疾病 干预专门针对他们的需求量身定制。因此，广泛的目标是降低慢性的风险 艾滋病毒积极的非洲裔美国男性疾病。 具体目的是测试理论的功效 - 基于上下文适当的健康促进干预措施，以引起链接的行为的积极变化 艾滋病毒阳性非裔美国人40岁以上的艾滋病毒阳性疾病的风险，并确定 介导其功效的理论变量。 该研究将利用随机对照试验。 这 参加者将为384名40岁或40岁以上的非裔美国人艾滋病毒阳性男性接受HAART的艾滋病毒。 这些人将被随机分为基于理论的适当健康促进干预措施 涉及每周三小时的干预课程或一个注意力控制组。 健康促进 干预将是基于与形成性的社会认知理论的干预措施的适应 研究并发现有效地遵守5日的饮食和体育锻炼指南 和申请人初步研究中的前列腺癌筛查指南。 数据将在 干预后3、6和12个月的基线，立即发布，这将允许评估短期 干预的期限和长期影响以及干预措施是否随着时间而变化。 声音的 计算机辅助的自我浏览将用于评估自我报告的遵守体育锻炼 准则，5次的水果和蔬菜指南，前列腺筛查指南以及结肠癌筛查 行为改变的准则和理论调解人。 客观结果将包括与健康相关的健身 （6分钟步行测试，1分钟的俯卧撑测试，1分钟的静坐测试，静坐测试），生理变量 （血压，体重指数，腰围和腰围比）以及前列腺癌和结肠癌 根据病历审查进行筛查。

项目成果

Reasoned Action Approach Correlates of Physical Activity Among African American Men Living With HIV: A Cross-Sectional Study.

合理的行动方法与感染艾滋病毒的非洲裔美国男性的身体活动相关：一项横断面研究。

• DOI: 10.1097/jnc.0000000000000196
• 发表时间: 2021
• 期刊: The Journal of the Association of Nurses in AIDS Care : JANAC
• 作者: Kelly,Terri-Ann;Woko,Chioma;Jemmott,LorettaS;Icard,Larry;Chittamuru,Deepti;Jemmott3rd,JohnB
• 通讯作者: Jemmott3rd,JohnB